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Chemotherapy regimen predicts steatohepatitis and an increase in 90-day mortality after surgery for hepatic colorectal metastases

Patients and their physicians should be careful when selecting a chemotherapy drug to treat colorectal cancer that has spread to the liver, say researchers at The University of Texas M. D. Anderson Cancer Center in Houston.

3 May 2006

Simple formula that will enable anesthesiologists to predict blood needs in heart surgery

Duke University Medical Center researchers have developed a simple formula that will enable anesthesiologists to predict, based on individual patient characteristics, how much blood to have on hand in the operating room prior to coronary artery bypass surgery.

3 May 2006

New vaccine against lethal avian influenza virus shows promise

A commercially developed vaccine has successfully protected mice and ferrets against a highly lethal avian influenza virus, according to the investigator who led the study at St. Jude Children's Research Hospital.

3 May 2006

Polymer-based therapy for breast cancer

Women who undergo surgery for breast cancer followed by radiation therapy often experience breast deformities that can only be corrected through reconstructive surgery.

3 May 2006

Link between colicky babies and postpartum depression

A compelling connection exists between colicky babies and postpartum depression, according to a study conducted by a Brown Medical School professor and Rhode Island Department of Health family health experts.

3 May 2006

Ultrasound-guided, intra-tendonous injection of a dextrose solution effective in treating chronic tendonoses in the leg

Ultrasound-guided, intra-tendonous injection of a dextrose solution is a very effective treatment for certain chronic tendonoses in the leg, reported radiologists from the department of radiology at St. Paul's Hospital and the Department of Family Practice at the University of British Columbia both in Vancouver, BC.

3 May 2006

The 30-year natural history of type 1 diabetes complications

...while cases of premature death and a few other complications have declined, rates of other serious diabetes-related disorders such as heart and eye disease have not improved over the past 25 to 30 years.

3 May 2006

Significant number of women believe their children are normal weight when they are actually overweight

Latina mothers of preschool-aged children frequently have inaccurate perceptions of their children's body mass index and believe they are healthy when they are overweight, according to a new study from the University of California, San Francisco.

2 May 2006

Genetic and environmental factors impact chronic fatigue syndrome patients

People who suffer from chronic fatigue syndrome (CFS) have a genetic make up that affects the body's ability to adapt to change, according to a series of papers released last week by the Centers for Disease Control and Prevention (CDC).

2 May 2006

Kidney patients warned away from potassium

Many kidney failure patients are increasing their chance of nerve damage in their legs and feet by simply having too much potassium in their diet, according to research carried out by the University of New South Wales (UNSW), the Prince of Wales Medical Research Institute (POWMRI) and the Prince of Wales Hospital.

2 May 2006

Sildenafil plus recreational drugs equals risky sexual behaviour

A new survey has found that a significant number of young men have used erectile dysfunction, (ED), medications such as Viagra often in conjunction with other recreational drugs, and most without consulting a physician.

1 May 2006

Transplanted stem cells hoped to be able to regenerate damaged heart muscle in first heart attack victims

Rush cardiologists are hoping that transplanted stem cells can regenerate damaged heart muscle in those who experience a first heart attack. The study involves an intravenous infusion of adult mesenchymal stem cells from healthy donor bone marrow that might possibly reverse damage to heart tissue.

28 Apr 2006

Finding indicate why some kinds of Leukemia are more aggressive than others

New clues to why some kinds of leukemia are more aggressive and deadly than others are coming from research examining the types of genetic damage that allow some blood cells to grow out of control, scientists report.

28 Apr 2006

Discovery brings embryonic stem cell medicine a step closer

A team of scientists announced a critical step on the path of realizing the promise of embryonic stem (ES) cells for medicine. The researchers have discovered unique molecular imprints coupled to DNA in mouse ES cells that help explain the cells' rare ability to form almost any body cell type. These imprints, or "signatures," appear near the master genes that control embryonic development and probably coordinate their activity in the early stages of cell differentiation. Not only do these findings help to unlock the basis for ES cells' seemingly unlimited potential, they also suggest ways to understand why ordinary cells are so limited in their abilities to repair or replace damaged cells.

26 Apr 2006

Studies indicate stem cells are flexible enough to become any cell in the body

Two studies in the April 21, 2006 Cell report new details of the "genetic program" that affords embryonic stem cells the flexibility to give rise to any cell type in the body. Both groups identified mechanisms by which the embryonic stem cells of mice or humans keep from going down any one particular developmental path--that of muscle or nervous tissue, for example--while remaining "poised for activation."

26 Apr 2006

Studies indicate stem cells are flexible enough to become any cell in the body

26 Apr 2006

Evidence explains relationship between television and poor diet in children

Researchers from the Harvard School of Public Health (HSPH) and Children's Hospital Boston found that kids who spend more time watching television also eat more of the calorie-dense, low-nutrient foods advertised on television. Previous studies had demonstrated that children who watch more television are more likely to be overweight, but this is the first time a research team has found evidence for a mechanism explaining that relationship.

26 Apr 2006

Caspase-12 antagonists could potentially be useful in the treatment of sepsis and other inflammatory and immune disorders

According to the new study, the presence of caspase-12, which appears to modulate inflammation and innate immunity in humans, increases the body's "vulnerability to bacterial infection and septic shock" while a deficiency confers strong resistance to sepsis. This new discovery suggests that caspase-12 antagonists could be a potentially useful in the treatment of sepsis and other inflammatory and immune disorders.

26 Apr 2006

Parents need to be helped to know how to talk about cancer with their children

Cancer is relatively common among women of childbearing age. Although the importance of communication with patients and their families has been recognised, relatively little has been published about communication with children when their parent is newly diagnosed as having cancer.

26 Apr 2006

Children of snorers, three times as likely to snore themselves

Children of parents who snore are three times more likely to snore themselves, according to a new study by researchers at Cincinnati Children's Hospital Medical Center. Furthermore, children who test positive for allergies are twice as likely to snore.

26 Apr 2006