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Isis commences ISIS-GCGRRx and ISIS-GCCRRx Phase 1 studies for type 2 diabetes

Isis Pharmaceuticals, Inc. announced today that it has initiated Phase 1 clinical studies for ISIS-GCGRRx and ISIS-GCCRRx, antisense drugs Isis is developing for the treatment of type 2 diabetes.

2 Nov 2011

Towards a cure for chronic fatigue syndrome

Two doctors at Haukeland University Hospital have made great progress in their work to solve chronic fatigue syndrome (CFS). Trials cancer medicine has improved the health of two out of three CFS patients.

2 Nov 2011

SGI HPC systems selected for genomics research at Kyoto University's Institute for Chemical Research

SGI, the trusted leader in technical computing, announced today that the Institute for Chemical Research at Kyoto University in Kyoto, Japan, has selected an SGI high performance computing (HPC) and storage system to advance genomics research at the Institute.

2 Nov 2011

World population reaches 7 billion amid warnings about health, natural resources

"Countries around the world marked the world's population reaching seven billion Monday with lavish ceremonies for newborn infants symbolizing the milestone and warnings that there may be too many humans for the planet's resources," the Associated Press/MSNBC.com reports.

2 Nov 2011

Study examines how perception of roles among ED staff can impact patient satisfaction

A study from Rhode Island Hospital examined how the perception of roles among emergency department staff can impact patient satisfaction. Through a web survey with embedded interventions, the researchers were able to determine where gaps exist in key indicators of patient satisfaction, while staff reported changing or reconsidering how these factors play into their roles.

2 Nov 2011

Hospitalized diabetic patients with acute kidney injury more likely to develop CKD

Findings from a recent University of Cincinnati (UC) and Cincinnati Department of Veterans Affairs (VA) Medical Center study show that multiple episodes of acute kidney injury during hospital stays for patients with diabetes are associated with a risk for developing chronic kidney disease.

2 Nov 2011

Articles explore clinical dilemma about children's behavioral problems

Clinicians often face the challenge of trying to make sense of conflicting reports from parents, teachers, and children about a child's behavioral problems. However, a better understanding of the source and nature of these disagreements may provide important information that could improve treatment and outcomes. A group of articles in the current issue of Journal of Child and Adolescent Psychopharmacology, a peer-reviewed journal published by Mary Ann Liebert, Inc., explores this challenging clinical dilemma.

2 Nov 2011

Inhibiting Notch signalling makes hormone-receptor positive cells dependent on estrogen

Within many hormone-receptor positive breast cancers lives a subpopulation of receptor-negative cells - knock down the hormone-receptor positive cells with anti-estrogen drugs and you may inadvertently promote tumor takeover by more dangerous, receptor-negative cells.

2 Nov 2011

No evidence of increased breast cancer risk for non-carriers of genetic mutations

Mothers, sisters and daughters from breast cancer families with known genetic mutations do not all share the same high risk of developing the disease, according to a new international study involving the University of Melbourne.

2 Nov 2011

Study identifies a group of middle school students at high risk for alcohol use

Research led by University of Southern California (USC) professor Mary Ann Pentz, Ph.D., shows that black middle school students whose close friends drink alcohol are more likely to drink alcohol in high school than their white classmates.

2 Nov 2011

NIH-funded project to discover biomarkers for type 2 diabetes

Arizona State University will lead a four-year, $5 million expanded initiative sponsored by the National Institutes of Health to discover proteins, or biomarkers, to help predict cardiovascular disease and to assess potential new treatments in people with type 2 diabetes.

2 Nov 2011

Researchers identify small-molecule drug candidates for many metabolic conditions

A new discovery by Californian scientists may lead to a pharmaceutical breakthrough for a wide range of illnesses that involve the hydration of cells that line the inner surfaces of our body's organs and tissues. In a new report appearing in the FASEB Journal, the researchers describe how they used high-throughput screening to identify small-molecule drug candidates which help cells bypass defective channels that normally move salt and water through cell membranes.

2 Nov 2011

Study finds multidrug-resistant Acinetobacter baumannii in 48% of infected patient rooms

Multidrug-resistant Acinetobacter baumannii (MDR-AB) was found in the environment of 48 percent of the rooms of patients colonized or infected with the pathogen, according to a new study published in the November issue of the American Journal of Infection Control, the official publication of APIC - the Association for Professionals in Infection Control and Epidemiology.

2 Nov 2011

Prostate cancer patients with bone metastases benefit from repeated 188Re-HEDP therapy

For prostate cancer patients with bone metastases, repeated administrations of radionuclide therapy with 188Re-HEDP are shown to improve overall survival rates and reduce pain, according to new research published in the November issue of The Journal of Nuclear Medicine.

2 Nov 2011

Johns Hopkins breast cancer researcher wins BioMaryland LIFE Prize

A Johns Hopkins breast cancer researcher is the recipient of a $50,000 award designed to encourage rapid translation of her basic research on biomarkers into a commercially available test that could predict the best treatment options for some women with breast cancer.

2 Nov 2011

ADHD medications do not increase risk of heart attack in children, young adults

Attention Deficit Hyperactivity Disorder (ADHD) medications do not increase the risk for heart disease or heart attack in children and young adults, according to a Vanderbilt study of 1.2 million patients taking drugs including Ritalin, Adderall, Concerta and Strattera between 1998 and 2005.

2 Nov 2011

E.U., UNICEF launch $430M fund in Zimbabwe to provide medical care to children, pregnant women

"A $430 million fund which will give Zimbabwean children and pregnant women free medical care at public hospitals was launched Monday with the help of the E.U. and UNICEF," Agence France-Presse reports.

2 Nov 2011

Targeted antibiotic safe and effective for irritable bowel syndrome

Among the most commonly used treatments for irritable bowel syndrome - which affects as many as 20 percent of the United States population - a targeted antibiotic was shown to be the safest in a new study by Cedars-Sinai researchers, based on an analysis of 26 large-scale clinical trials.

2 Nov 2011

Penn surgeons perform first bilateral hand transplantation

For the first time in the Delaware Valley Region, a patient has undergone a complex and intricate bilateral hand transplant that could significantly enhance the quality-of-life for persons with multiple limb loss.

2 Nov 2011

Vitamin D does not confer benefits against mortality in postmenopausal women

Doctors agree that vitamin D promotes bone health, but a belief that it can also prevent cancer, cardiovascular disease and other causes of death has been a major health controversy. Consistent with advice issued last fall by the Institute of Medicine, a new study finds that vitamin D did not confer benefits against mortality in postmenopausal women after controlling for key health factors such as abdominal obesity.

2 Nov 2011

Medicine News and Research

Isis commences ISIS-GCGRRx and ISIS-GCCRRx Phase 1 studies for type 2 diabetes

Towards a cure for chronic fatigue syndrome

SGI HPC systems selected for genomics research at Kyoto University's Institute for Chemical Research

World population reaches 7 billion amid warnings about health, natural resources

Study examines how perception of roles among ED staff can impact patient satisfaction

Hospitalized diabetic patients with acute kidney injury more likely to develop CKD

Articles explore clinical dilemma about children's behavioral problems

Inhibiting Notch signalling makes hormone-receptor positive cells dependent on estrogen

No evidence of increased breast cancer risk for non-carriers of genetic mutations

Study identifies a group of middle school students at high risk for alcohol use

NIH-funded project to discover biomarkers for type 2 diabetes

Researchers identify small-molecule drug candidates for many metabolic conditions

Study finds multidrug-resistant Acinetobacter baumannii in 48% of infected patient rooms

Prostate cancer patients with bone metastases benefit from repeated 188Re-HEDP therapy

Johns Hopkins breast cancer researcher wins BioMaryland LIFE Prize

ADHD medications do not increase risk of heart attack in children, young adults

E.U., UNICEF launch $430M fund in Zimbabwe to provide medical care to children, pregnant women

Targeted antibiotic safe and effective for irritable bowel syndrome

Penn surgeons perform first bilateral hand transplantation

Vitamin D does not confer benefits against mortality in postmenopausal women

Everything there is to know about biosimilars eBook

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

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