Bacterial News and Research

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MenB bacterium uses Adhesin Complex Protein to stick to human cells

Scientists at the University of Southampton have taken a significant and important step in keeping people safe from the most common form of meningitis in the UK.

28 Feb 2013

New research reveals special face masks prevent clinical respiratory and bacterial infections

Health care workers who consistently wear special fitted face masks while on duty are much less likely to get clinical respiratory and bacterial infections, according to new research led by University of New South Wales academics.

27 Feb 2013

‘Traffic light’ guide for pediatric bacterial infection needs refining

Study results suggest that a “traffic light” system for categorizing the severity of infections in children fails to detect a substantial number of serious bacterial infections, particularly urinary tract infections.

26 Feb 2013

Xellia to develop new antibiotics effective against multi-drug resistant Gram-negative bacteria

Xellia Pharmaceuticals, a fully integrated specialty pharmaceutical company focusing on the global anti-infective market, announced today that it is developing new antibiotics effective against multi-drug resistant (MDR), Gram-negative bacteria.

26 Feb 2013

Experts analyse biological function of Shewanella-like protein phosphatase

Experts have disabled a unique member of the signalling proteins which are essential for the development of the malaria parasite. They have produced a mutant lackingthe ancient bacterial Shewanella-like protein phosphatase known as SHLP1 (pronounced shelph). This mutant is unable to complete its complex life cycle and is arrested in its development in the mosquito.

26 Feb 2013

Vanderbilt investigators report new insights into workings of calprotectin

On the front lines of our defenses against bacteria is the protein calprotectin, which "starves" invading pathogens of metal nutrients. Vanderbilt investigators now report new insights to the workings of calprotectin - including a detailed structural view of how it binds the metal manganese.

22 Feb 2013

International nonproprietary name “auriclosene” approved by WHO for NovaBay’s NVC-422

NovaBay® Pharmaceuticals, Inc. (NYSE MKT: NBY), a biotechnology company focused on addressing the large unmet therapeutic needs of the global anti-infective market with first-in-class compounds such as its proprietary Aganocides®, today announced that the World Health Organization (WHO) has approved the international nonproprietary name (INN) “auriclosene” (pronounced awr-rih-CLO-zeen) for the Company’s lead Aganocide® compound NVC-422.

21 Feb 2013

Dietary impacts, health changes and oral pathogen genomic evolution

DNA preserved in calcified bacteria on the teeth of ancient human skeletons has shed light on the health consequences of the evolving diet and behaviour from the Stone Age to the modern day.

18 Feb 2013

Two studies discover new enzyme that acts as a sensor of innate immunity

Two studies by researchers at UT Southwestern Medical Center could lead to new treatments for lupus and other autoimmune diseases and strengthen current therapies for viral, bacterial, and parasitic infections.

16 Feb 2013

Protein test may help identify bacterial COPD exacerbations

Increased serum levels of pancreatic stone protein/regenerating protein may help identify bacteria-related exacerbations of chronic obstructive pulmonary disease, say researchers.

15 Feb 2013

Researchers discover SCANR that helps protect a cell's genes against DNA interlopers

Gene wars rage inside our cells, with invading DNA regularly threatening to subvert our human blueprint. Now, building on Nobel-Prize-winning findings, UC San Francisco researchers have discovered a molecular machine that helps protect a cell's genes against these DNA interlopers.

15 Feb 2013

Researchers ESTABLISH efficacy of tedizolid phosphate for skin infections

Results from the phase III ESTABLISH-1 study show that the new antibiotic tedizolid phosphate is noninferior to linezolid for the treatment of acute bacterial and skin structure infections.

14 Feb 2013

GSK1322322 targets gram-positive bacteria including methicillin-resistant strains of MRSA

An increasing number of bacteria is evolving antibiotic resistance. Much-feared representatives of this steadily growing group include Staphylococci strains. At this point, multi-resistant forms of the bacterium Staphylococcus aureus - the "hospital germ" known commonly by its acronym, MRSA - can only be treated with a select subset of antibiotics as many drugs have simply stopped working. This is precisely why the field of medicine is in desperate need of new treatment options.

14 Feb 2013

Combining synthetic and natural toxins could disarm cancer, drug-resistant bacteria

Cancer researchers from Rice University suggest that a new man-made drug that's already proven effective at killing cancer and drug-resistant bacteria could best deliver its knockout blow when used in combination with drugs made from naturally occurring toxins.

13 Feb 2013

Bronchiectasis finding reveals COPD patients at mortality risk

Bronchiectasis is independently associated with mortality risk among patients with moderate-to-severe chronic obstructive pulmonary disease, Spanish research shows.

12 Feb 2013

U.S. hospitals continue to make progress in reducing health care-associated infections

Hospitals in the U.S. continue to make progress in the fight against central line-associated bloodstream infections and some surgical site infections, according to a report issued today by the Centers for Disease Control and Prevention (CDC). Catheter-associated urinary tract infections remained unchanged between 2010 and 2011.

12 Feb 2013

Pmt transport system helps develop new type of drug against S. aureus infection

National Institutes of Health (NIH) scientists have identified a promising lead for developing a new type of drug to treat infection caused by Staphylococcus aureus, a bacterium that frequently resists traditional antibiotics.

11 Feb 2013

Infusions of regulatory T cells turn off autoimmune attack on joints

Farber Cancer Institute scientists have demonstrated a new strategy for treating autoimmune disease that successfully blocked the development of rheumatoid arthritis in a mouse model. They say it holds promise for improved treatment of arthritis and other autoimmune disorders in people.

10 Feb 2013

Tat-beclin 1 shows promise against infections, neurodegenerative disorders and cancer

UT Southwestern Medical Center scientists have synthesized a peptide that shows potential for pharmaceutical development into agents for treating infections, neurodegenerative disorders, and cancer through an ability to induce a cell-recycling process called autophagy.

10 Feb 2013

Highlights for Feb. 2013 issue of Genetics journal

Listed below are the selected highlights for the February 2013 issue of the Genetics Society of America's journal, Genetics.

10 Feb 2013

Bacterial News and Research

MenB bacterium uses Adhesin Complex Protein to stick to human cells

New research reveals special face masks prevent clinical respiratory and bacterial infections

‘Traffic light’ guide for pediatric bacterial infection needs refining

Xellia to develop new antibiotics effective against multi-drug resistant Gram-negative bacteria

Experts analyse biological function of Shewanella-like protein phosphatase

Vanderbilt investigators report new insights into workings of calprotectin

International nonproprietary name “auriclosene” approved by WHO for NovaBay’s NVC-422

Dietary impacts, health changes and oral pathogen genomic evolution

Two studies discover new enzyme that acts as a sensor of innate immunity

Protein test may help identify bacterial COPD exacerbations

Researchers discover SCANR that helps protect a cell's genes against DNA interlopers

Researchers ESTABLISH efficacy of tedizolid phosphate for skin infections

GSK1322322 targets gram-positive bacteria including methicillin-resistant strains of MRSA

Combining synthetic and natural toxins could disarm cancer, drug-resistant bacteria

Bronchiectasis finding reveals COPD patients at mortality risk

U.S. hospitals continue to make progress in reducing health care-associated infections

Pmt transport system helps develop new type of drug against S. aureus infection

Infusions of regulatory T cells turn off autoimmune attack on joints

Tat-beclin 1 shows promise against infections, neurodegenerative disorders and cancer

Highlights for Feb. 2013 issue of Genetics journal

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