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Clinical trial shows promising results for treatment of patients with recurrent high-grade glioma

New data from a Phase I clinical trial led by Clark Chen, M.D., Ph.D., Lyle French Chair in Neurosurgery and Head of the University of Minnesota Medical School Department of Neurosurgery shows more than a quarter of patients with recurrent high-grade glioma, a form of brain cancer, were alive more than three years after treatment.

28 Oct 2017

Researchers find link between disrupted energy production and late-onset Alzheimer's disease

A team of investigators from McLean Hospital and Harvard Medical School, led by Kai C. Sonntag, MD, PhD, and Bruce M. Cohen, MD, PhD, has found a connection between disrupted energy production and the development of late-onset Alzheimer's disease (LOAD). The findings appear in the current issue of Scientific Reports.

27 Oct 2017

New device that fits on a key chain can accurately test for allergens

More than 50 million Americans have food allergies and often just trace amounts of allergens can trigger life-threatening reactions.

26 Oct 2017

Penn researchers awarded $3.75 million grant to investigate how meal timings affect human health

Disrupting sleep-wake cycles from a predominantly daytime to a delayed eating lifestyle, -- i.e., skipping breakfast and making lunch the first meal of the day, plus eating late dinner, disrupts the body's natural circadian (24-hour) rhythm, the cycle that tells us when to sleep, wake up, eat, and influences hormones and other functions.

26 Oct 2017

Penn study sheds light on genetic cause of early hearing loss

From the moment a baby is born, they are put through a battery of screenings to test for all sorts of characteristics, which includes the sense of hearing.

26 Oct 2017

Smell sensitivity changes over the course of each day, study suggests

It has always been apparent that some individuals have a better sense of smell than others, but a new study of 37 teens provides the first direct evidence that within each person, smell sensitivity varies over the course of each day. The pattern, according to the data, tracks with the body's internal day-night cycle, or circadian rhythm.

26 Oct 2017

Study shows efficacy of antipsychotic as adjunctive therapy for gastroparesis in emergency department

Haloperidol is an effective first-line agent in combination with standard analgesic and antiemetic agents for the treatment of gastroparesis in the emergency department.

26 Oct 2017

Genetic variability of Helicobacter pylori complicates efforts to develop effective vaccine

Helicobacter pylori is a widespread bacterial pathogen that infects the lining of the stomach, where it can cause ulcers and even cancer. As a new study shows, its genetic variability complicates efforts to develop an effective vaccine.

25 Oct 2017

Direct application of immune cells accelerates healing of acute, chronic wounds in mice

A Massachusetts General Hospital research team has found a surprising potential solution to a persistent clinical problem - the healing of chronic wounds. In their report published in Wound Repair and Regeneration, the investigators from the MGH Vaccine and Immunotherapy Center describe how application of mature B lymphocytes - the immune cells best known for producing antibodies - greatly accelerated the healing of acute and chronic wounds in both diabetic and nondiabetic mice.

25 Oct 2017

New study hopes to shed light on mechanism behind epileptic and non-epileptic seizures

Seizures are a common result of traumatic brain injury, especially in military veterans. A new study funded by the DOD, Congressionally Directed Medical Research Programs, and conducted in Providence RI and Birmingham AL hopes to shed new light on the mechanism behind seizures associated with post-traumatic epilepsy and psychogenic nonepileptic seizures.

25 Oct 2017

Study shows feasibility of home monitoring to detect heart arrhythmias in developing fetuses

As reported in the Journal of Perinatology, researchers from Children's Hospital Colorado (Children's Colorado) recently confirmed that it is feasible for at-risk pregnant women to use commercially-available Doppler fetal heart rate monitors for home monitoring to detect heart arrhythmias in their developing fetuses.

25 Oct 2017

Developmental abnormality discovered in babies linked to SIDS

International research involving the University of Adelaide has uncovered a developmental abnormality in babies - especially in premature babies and in boys - that for the first time has been directly linked to cases of sudden infant death syndrome (SIDS).

25 Oct 2017

Pollutant from forest and crop fires induces genetic damage in human lung cells

When exposed in a laboratory to pollution levels comparable to those found in the atmosphere of the Amazon region during the forest and crop burning season, human lung cells suffer severe DNA damage and stop dividing. After 72 hours of exposure, over 30% of the cultured cells are dead.

24 Oct 2017

Genomic roots of ovarian tumors may arise in fallopian tubes, study suggests

Some scientists have suspected that the most common form of ovarian cancer may originate in the fallopian tubes, the thin fibrous tunnels that connect the ovaries to the uterus.

24 Oct 2017

Penn researchers provide new insights into how Notch drives growth of B-cell cancers

Notch is one of the most frequently mutated genes in chronic lymphocytic leukemia (CLL), the most common leukemia in adults in the United States. It is also often mutated in other common B cell tumors, such as mantle cell lymphoma.

23 Oct 2017

Study offers solution to protect against vaccine-enhanced respiratory disease

Researchers have discovered that a virus-like particle vaccine can prime the body's immune response and prevent the severe respiratory disease that results when patients given an early form of a vaccine for respiratory syncytial virus (RSV) are exposed to RSV, according to a study led by Georgia State University.

23 Oct 2017

Rutgers researchers to explore ways for tackling emerging fungal infections

In recent years, hospitals nationwide have been reporting an increase in life-threatening illnesses resulting from a deadly fungal infection caused by the yeast Candida auris that can enter the bloodstream. This yeast is difficult to identify and often does not respond to commonly used antifungal drugs, leading to high mortality.

23 Oct 2017

Proton beam therapy has lower rates of toxicity in pediatric patients with head and neck cancer

Pediatric patients with head and neck cancer can be treated with proton beam therapy (PBT) instead of traditional photon radiation, and it will result in similar outcomes with less impact on quality of life.

23 Oct 2017

Study shows link between symptom burden and use of health care services in advanced cancer patients

Hospitalized patients with advanced cancer who report more intense and numerous physical and psychological symptoms appear to be at risk for longer hospital stays and unplanned hospital readmissions.

23 Oct 2017

Study elucidates how obesity makes breast cancer more aggressive

Obesity leads to the release of cytokines into the bloodstream which impact the metabolism of breast cancer cells, making them more aggressive as a result. Scientists from Helmholtz Zentrum München, Technische Universität München, and Heidelberg University Hospital report on this in 'Cell Metabolism'. The team has already been able to halt this mechanism with an antibody treatment.

23 Oct 2017

Medical School News and Research

Clinical trial shows promising results for treatment of patients with recurrent high-grade glioma

Researchers find link between disrupted energy production and late-onset Alzheimer's disease

New device that fits on a key chain can accurately test for allergens

Penn researchers awarded $3.75 million grant to investigate how meal timings affect human health

Penn study sheds light on genetic cause of early hearing loss

Smell sensitivity changes over the course of each day, study suggests

Study shows efficacy of antipsychotic as adjunctive therapy for gastroparesis in emergency department

Genetic variability of Helicobacter pylori complicates efforts to develop effective vaccine

Direct application of immune cells accelerates healing of acute, chronic wounds in mice

New study hopes to shed light on mechanism behind epileptic and non-epileptic seizures

Study shows feasibility of home monitoring to detect heart arrhythmias in developing fetuses

Developmental abnormality discovered in babies linked to SIDS

Pollutant from forest and crop fires induces genetic damage in human lung cells

Genomic roots of ovarian tumors may arise in fallopian tubes, study suggests

Penn researchers provide new insights into how Notch drives growth of B-cell cancers

Study offers solution to protect against vaccine-enhanced respiratory disease

Rutgers researchers to explore ways for tackling emerging fungal infections

Proton beam therapy has lower rates of toxicity in pediatric patients with head and neck cancer

Study shows link between symptom burden and use of health care services in advanced cancer patients

Study elucidates how obesity makes breast cancer more aggressive

Industry Focus eBook - Forensics & toxicology (2nd edition) eBook

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

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