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Dissimilar interaction of opioid receptors may explain why men, women experience pain differently

Women and men experience pain, particularly chronic pain, very differently. The ability of some opioids to relieve pain also differs between women and men. While it has been recognized since the mid-nineties that some narcotic analgesics are more effective in women than men, the reason for this difference was largely unknown.

19 Aug 2011

Seven research teams across the U.S. to develop new drugs for nervous system disorders

The National Institutes of Health has made awards to investigators across the United States for an ambitious set of projects seeking to develop new drugs for disorders of the nervous system.

19 Aug 2011

Lucentis receives Health Canada approval for treatment of retinal vein occlusion

Following a priority review, Health Canada has approved Lucentis (ranibizumab) as a treatment for vision loss resulting from retinal vein occlusion (RVO). This makes Lucentis the first approved treatment of its class in Canada for this debilitating condition. Patients will now have access to a treatment that is proven to be effective and has an established safety profile.

18 Aug 2011

Vitamin C shows promise against Alzheimer's disease

Researchers at Lund University have discovered a new function for vitamin C. Treatment with vitamin C can dissolve the toxic protein aggregates that build up in the brain in Alzheimer's disease.

18 Aug 2011

ACS honors MIT professor with Priestley Medal for controlled-release drug discovery

Robert S. Langer, Sc.D., the David H. Koch Institute Professor at Massachusetts Institute of Technology, has been named winner of the 2012 Priestley Medal by the American Chemical Society.

18 Aug 2011

Fluctuations in brain signals explained: Spontaneous electrical background rhythms in the brain influence fMRI

Until now, brain scans obtained using fMRI – one of the most important imaging methods in use today – have been affected by fluctuations in the brain activity measured which could not be explained. Researchers at the Max Planck Institute for Human Cognitive and Brain Sciences in Leipzig and the Charité in Berlin have now shown that certain electric background rhythms in the brain, known as Alpha oscillations, alter the fMRI signal obtained with visual stimuli. To do this, they used a new approach in which quickly changing brain activity, which cannot be captured by the scanner, was measured using

16 Aug 2011

Modified Cdk5 enzyme triggers damage to nerve cell connections in human Alzheimer's brains

Alzheimer's disease is characterized by abnormal proteins that stick together in little globs, disrupting cognitive function. These sticky proteins are mostly made up of beta-amyloid peptide. A better understanding of these proteins, how they form, and how they affect brain function will no doubt improve the diagnosis and treatment of Alzheimer's disease.

16 Aug 2011

Scientists identify potential new target for childhood eye tumor

A research team led by St. Jude Children's Research Hospital scientists has identified a potential new target for treatment of the childhood eye tumor retinoblastoma.

16 Aug 2011

AHRQ's new Spanish-language guide on heart medications

A free, illustrated easy-to-read pamphlet that compares drugs for preventing heart attacks, heart failure or strokes in people with stable coronary heart disease is one of six new Spanish-language publications from HHS' Agency for Healthcare Research and Quality that help patients compare treatments for common illnesses.

16 Aug 2011

Pain care management needs to be improved: CMAJ

Pain care management needs to be improved, with health care professionals committing to improve care as well as a retooling of the health care system to help people who are suffering, states an editorial in CMAJ.

16 Aug 2011

Vampire bat causes rabies

The Centers for Disease Control and Prevention (CDC) announced the first death linked to a vampire bat. The victim’s mother reported that her son was bitten by a vampire bat on his heel while he was sleeping. At the time, the bite was not reported or treated in Mexico, where the bite occurred.

15 Aug 2011

Researchers describe novel skin-mounted electronics in Science journal

Engineers have developed a device platform that combines electronic components for sensing, medical diagnostics, communications and human-machine interfaces, all on an ultrathin skin-like patch that mounts directly onto the skin with the ease, flexibility and comfort of a temporary tattoo.

12 Aug 2011

Insight into how molecular motor proteins save energy

The transport system inside living cells is a well-oiled machine with tiny protein motors hauling chromosomes, neurotransmitters and other vital cargo around the cell. These molecular motors are responsible for a variety of critical transport jobs, but they are not always on the go. They can put themselves into "energy save mode" to conserve cellular fuel and, as a consequence, control what gets moved around the cell, and when.

12 Aug 2011

New model for amyotrophic lateral sclerosis

By isolating cells from patients' spinal tissue within a few days after death, researchers funded by the National Institutes of Health have developed a new model of the paralyzing disease amyotrophic lateral sclerosis.

12 Aug 2011

Women with depression at higher risk of stroke

A new study published this week shows that depression puts middle-aged and older women at significant risk of suffering potentially debilitating strokes.

12 Aug 2011

SIGMAR1 gene mutation associated with development of juvenile ALS

Researchers from the Kingdom of Saudi Arabia have identified a mutation on the SIGMAR1 gene associated with the development of juvenile amyotrophic lateral sclerosis.

12 Aug 2011

Pacira second quarter total revenues increase to $3.6 million

Pacira Pharmaceuticals, Inc., an emerging specialty pharmaceutical company, today announced financial results for the second quarter ended June 30, 2011, provided an update on the execution of its pre-commercial and launch strategies for EXPAREL, and updated its 2011 financial guidance.

11 Aug 2011

InVivo Therapeutics reports net loss of $1,370,000 for second quarter 2011

InVivo Therapeutics Holdings Corp., a company focused on the development of groundbreaking technologies for the treatment of spinal cord injuries (SCI), today reported financial results for the three and six months ended June 30, 2011 and provided a business update.

11 Aug 2011

Study finds sharp increase in CT scan use in ED between 1996-2007

A review of national data from 1996 through 2007 reveals a sharp uptick in the use of computed tomography, or CT, scans to diagnose illnesses in emergency departments, a University of Michigan Health System study finds.

11 Aug 2011

Scientists identify 29 new genetic variants linked to multiple sclerosis

Scientists have identified 29 new genetic variants linked to multiple sclerosis, providing key insights into the biology of a very debilitating neurological disease. Many of the genes -implicated in the study are relevant to the immune system, shedding light onto the immunological pathways that underlie the development of multiple sclerosis.

11 Aug 2011