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Abbott, Biogen Idec announce additional results from daclizumab HYP Phase 2b trial for RRMS

Today Biogen Idec and Abbott announced additional results from the SELECT Phase 2b trial, the first of two registrational studies designed to evaluate the investigational compound daclizumab high-yield process in people with relapsing-remitting multiple sclerosis.

22 Oct 2011

Small molecule selectively blocks gene activity regulated by thyroid hormone

A small molecule developed at St. Jude Children's Research Hospital advances progress toward more tailored drugs in research that also offers insight into the biology of thyroid hormone.

22 Oct 2011

Old age not synonymous with impairment and disability

Exceptional cognitive and physical function in old age leaves a tell-tale immunologic fingerprint, say researchers at the University of Pittsburgh and Children's Hospital of Pittsburgh of UPMC. Likewise, older adults who have mild impairments bear a distinct immunologic pattern, too, according to findings published today in the Public Library of Science: One.

22 Oct 2011

Brazil to become world supplier of Chagas disease treatment

"Brazil is keen to take part in the international effort to expand access to medicines and to produce its own drugs, and will start by becoming the world supplier of medicines to treat Chagas disease," Health Minister Alexandre Padilha announced "at the World Conference on Social Determinants of Health, which opened Tuesday October 19 in Rio de Janeiro," Inter Press Service reports.

22 Oct 2011

Microbiome and its role in gastric and estrogen-related cancers

In the October 20th edition of the journal Cell Host and Microbe, Drs. Claudia Plottel and Martin J. Blaser of the Departments of Medicine and Microbiology at NYU Langone Medical Center, and the Department of Biology at New York University, present a model for understanding how cancer evolves in humans based on an understanding of the bacteria living in our body, the microbiome.

22 Oct 2011

New mathematical models can predict prostate cancer aggressiveness

Alexander R. A. Anderson, Ph.D., co-director of Integrative Mathematical Oncology (IMO) at Moffitt Cancer Center, and his colleagues, Simon Hayward, Ph.D., at Vanderbilt University and Gustavo Ayala, M.D., at Baylor College of Medicine, have received a five-year, $3 million grant from the National Institutes of Health to create new mathematical models to predict prostate cancer aggressiveness.

22 Oct 2011

NIH stops triple-drug therapy clinical trial for idiopathic pulmonary fibrosis

The National Heart, Lung, and Blood Institute (NHLBI), part of the National Institutes of Health, has stopped one arm of a three arm multi-center, clinical trial studying treatments for the lung-scarring disease idiopathic pulmonary fibrosis (IPF) for safety concerns.

22 Oct 2011

NIPPV helps decrease mortality rates among hospitalized COPD patients

Although increased use of noninvasive positive-pressure ventilation (NIPPV) nationwide has helped decrease mortality rates among patients hospitalized with chronic obstructive pulmonary disease (COPD), a small group of patients requiring subsequent treatment with invasive mechanical ventilation (IMV) have a significantly higher risk of death than those placed directly on IMV, according to researchers in the United States who studied patterns of NIPPV use.

22 Oct 2011

Three major patterns emerge among couples dealing with male depression

University of British Columbia researchers have identified three major patterns that emerge among couples dealing with male depression. These can be described as "trading places," "business as usual" and "edgy tensions."

22 Oct 2011

ADA supports IOM's report on front-of-package food labeling

The American Dietetic Association supports a report released today by the Institute of Medicine calling for a standardized system for front-of-package food labeling that can be easily understood by most consumers.

22 Oct 2011

Researchers identify cancer cell cycle-regulated mechanism

Researchers from the NYU Cancer Institute, an NCI-designated cancer center at NYU Langone Medical Center, have identified a cell cycle-regulated mechanism behind the transformation of normal cells into cancerous cells.

22 Oct 2011

New sleepwear now available for post-surgery breast cancer patients

For breast cancer patients, surgery is often the first line of treatment. Following surgery, patients must deal not only with the healing process, but also with lasting after effects such as scarring, skin sensitivity and body asymmetry. A new line of sleepwear now available to breast cancer survivors is the result of an ongoing research partnership between Ryerson University and Princess Margaret Hospital that examines how the side effects of surgery and treatment affect women's physical comfort, confidence and sexuality.

22 Oct 2011

CHEMM-IST helps first responders to identify hazardous chemical exposure

Exposure to hazardous chemicals can cause serious illness quickly, but emergency medical providers often don't know the key piece of information that determines treatment: Which of the tens of thousands of toxic chemicals is making patients sick?

22 Oct 2011

Common risk factors for hepatocellular cancer

Among known risk factors for hepatocellular cancer, smoking, obesity, and heavy alcohol consumption, along with chronic hepatitis B and C infection, contribute to a large share of the disease burden in Europe, according to a cohort study published online October 21 in the Journal of the National Cancer Institute.

22 Oct 2011

ACP applauds CMS' improved Medicare ACO Final rule

The American College of Physicians (ACP) today applauded CMS for making substantial improvements in its long- awaited Final Rule on Accountable Care Organizations.

22 Oct 2011

Boehringer Ingelheim announces new data from hepatitis C virus portfolio

Boehringer Ingelheim announced today that new data from its hepatitis C virus (HCV) portfolio will be presented in scientific sessions at The Liver Meeting 2011, the 62nd Annual Meeting of the American Association for the Study of Liver Diseases (AASLD), taking place November 4 - November 8 in San Francisco, CA.

22 Oct 2011