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Study finds why corticosteroids do not work well for COPD patients

Chronic obstructive pulmonary disease (COPD) leads to persistent inflammation of the airways and is typically managed with corticosteroids, a class of anti-inflammatory medication. However, corticosteroids do not improve survival nor alter the progression of COPD and may reduce lung symptoms as little as 20 percent.

19 Oct 2011

Study finds 30% decline in heart failure hospitalization rate

Being hospitalized for heart failure (HF) was about 30 percent less likely in 2008 than in 1998, according to a study by Yale physicians in the Oct. 19 issue of JAMA. The team also found that the rate of hospitalization for black men dropped at a lower rate, and that one-year mortality rates declined slightly during this period, but remained high.

19 Oct 2011

Roundup: Mass. contemplates 'global payments'; rural hospitals struggling; Oregon liability cost studied

Although important details remain to be negotiated, the legislative leaders and Gov. Deval Patrick, all Democrats, are working toward a plan that would encourage flat "global payments" to networks of providers for keeping patients well, replacing the fee-for-service system that creates incentives for excessive care by paying for each visit and procedure.

19 Oct 2011

King's researchers create traditional Chinese medicine database

A comprehensive database developed by King's College London researchers that features the chemical components found in traditional Chinese medicines has been released to market this month, allowing researchers to explore age-old remedies in the search for tomorrow's new drugs.

19 Oct 2011

Viewpoints: CLASS decision ends fear of government bailout; the strengths and failings of U.S. health care

The problem, as numerous experts warned at the time, was whether the program could be run, as the law required, in a way that made it financially solvent for at least 75 years. The difficulty with the CLASS Act was ensuring that premiums could be set low enough to attract widespread participation but high enough to pay tbenefits. The risk was that the program would attract the sickest participants, who thought they might need its protections, and thereby drive premium prices ever higher in a spiral of dysfunctionhe promised.

19 Oct 2011

Heart-failure related hospitalizations has declined substantially among Medicare patients

Between 1998 and 2008, heart-failure related hospitalizations declined substantially among Medicare patients, but at a lower rate for black men, according to a study in the October 19 issue of JAMA. Also, 1-year mortality rates declined slightly during this period, but remain high.

19 Oct 2011

RTS,S vaccine reduces risk of severe malaria in African children

First results from a large-scale Phase III trial of RTS,S, published online today in the New England Journal of Medicine (NEJM), show the malaria vaccine candidate to provide young African children with significant protection against clinical and severe malaria with an acceptable safety and tolerability profile.

19 Oct 2011

Susan G. Komen-funded project targets genetic complexity of breast tumors

By analyzing which animal models of breast cancer best compare to human cases, a Michigan State University researcher is hoping to overcome one of the most significant barriers in treating the deadly disease: The genetic complexity of the tumors themselves.

19 Oct 2011

“Binge drinking is binge spending” for the individual as well as the State: Report

Binge drinking is costing the U.S. economy more than $200 billion a year, mostly in lost workplace productivity, a U.S. health agency said on Monday.

18 Oct 2011

First results from phase 3 malaria vaccine candidate trial

18 Oct 2011

New promise of a malaria vaccine

New results published today in the New England Journal of Medicine about a large-scale Phase III trial conducted in seven African countries of the malaria vaccine candidate RTS,S deserve a hearty round of applause.

18 Oct 2011

Yearly mammogram after 40 has high rate of false alarms: Study

Latest evidence suggests that getting a mammogram each year after age 40 may not be a good idea. A study suggests that far fewer women would be put through the anxiety of being called back for a second mammogram and unnecessary biopsies if screening took place every two years.

18 Oct 2011

Effective liability reform could reduce hospital admissions

Visits to emergency departments climbed nearly 10 percent in one year to a new high of more than 136 million visits in 2009, according to preliminary estimates from the Centers for Disease Control and Prevention (CDC), just as emergency physicians are releasing new studies showing an association between medical liability concerns and rising hospital admissions from the emergency department.

18 Oct 2011

Commercialization strategies for next-generation medicines

The Center for Biotechnology at Stony Brook University, in collaboration with Demy-Colton Life Science Advisors, and key opinion leaders from the biotech and biopharmaceutical industries, academia, medical research foundations, and investment community, has organized a two-day event to forge partnerships to accelerate the development of new treatments for some of the world's most devastating diseases affecting millions.

18 Oct 2011

New Regenstrief initiative to encourage and propel innovation

Integrating some of the best new practices of industry into the strengths of the academic research process, the Regenstrief Institute is launching an initiative to encourage and propel innovation. The Institute has over 40 years of experience as an international leader in improving healthcare delivery.

18 Oct 2011

AR gene has opposite effects on prostate and breast cancers

Researchers at Cleveland Clinic have discovered that a gene - known as an androgen receptor (AR) - is found in both prostate and breast cancers yet has opposite effects on these diseases.

18 Oct 2011

One in four kindergarten children have difficulty in distinguishing medicine and candy

More than one in four kindergarten children, and one in five teachers, had difficulty distinguishing between medicine and candy in new research conducted by two, now seventh-grade students, who presented their findings on Monday, Oct. 17, at the American Academy of Pediatrics (AAP) National Conference and Exhibition in Boston.

18 Oct 2011

AICR recommends intake of cancer-fighting foods

Colleen Spees has always been interested in the role that diet played in disease, and set her sights on a career where she would counsel patients and train future dietitians. With multiple family members diagnosed with various types of cancer, Colleen decided to make the transition from clinical professional and nutrition educator to research scientist.

18 Oct 2011

HMS launches Initiative in Systems Pharmacology

Taking aim at the alarming slowdown in the development of new and lifesaving drugs, Harvard Medical School is launching an Initiative in Systems Pharmacology, a comprehensive strategy to transform drug discovery by convening biologists, chemists, pharmacologists, physicists, computer scientists and clinicians to explore together how drugs work in complex systems.

18 Oct 2011

National Centre for Bowel Research and Surgical Innovation to be set up in London

A national research centre for bowel disease is to be set up in London to bring the Cinderella area of medicine to the forefront of surgical innovation.

18 Oct 2011