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So much care it hurts: Unneeded scans, therapy, surgery only add to patients’ ills

When Annie Dennison was diagnosed with breast cancer last year, she readily followed advice from her medical team, agreeing to harsh treatments in the hope of curing her disease.

23 Oct 2017

Systematic review finds lack of data on medical cannabis use in children and adolescents

A systematic review of published studies on the use of medical cannabis in children and adolescents finds a notable lack of studies and a minimal number of the randomized, controlled trials needed to confirm the effectiveness of a treatment.

23 Oct 2017

Research finds decrease in opioid use among patients recovering from hip and knee replacement

Opioid use in patients recovering from hip and knee replacement decreased by one-third between 2006 and 2014, reflecting success in efforts to promote a multimodal approach to pain management (using a variety of methods to manage pain) rather than using opioids alone, reveals new research being presented at the ANESTHESIOLOGY 2017 annual meeting.

23 Oct 2017

Experts create quality improvement blueprint to reduce repetitive lab tests for hospitalized patients

In a review article publishing this week in JAMA Internal Medicine, physicians at Johns Hopkins, along with experts from several other institutions across north America, compiled published evidence and crafted an experience-based quality improvement blueprint to reduce repetitive lab testing for hospitalized patients.

20 Oct 2017

Kidney failure linked to lower quality of life, psychosocial challenges in young adults

Kidney failure is associated with lower quality of life in young people and limited employment, independence, and relationships compared with healthy peers, according to an analysis appearing in an upcoming issue of the Clinical Journal of the American Society of Nephrology

20 Oct 2017

Brain-training could help elderly people increase their understanding of words in noisy situations

For many people with hearing challenges, trying to follow a conversation in a crowded restaurant or other noisy venue is a major struggle, even with hearing aids. Now, Mass. Eye and Ear researchers reporting in Current Biology on October 19th have some good news: time spent playing a specially designed, brain-training audiogame could help.

19 Oct 2017

Study finds mitochondrial DNA damage in Veterans with Gulf War illness

Researchers say they have found the "first direct biological evidence" of damage in veterans with Gulf War illness to DNA within cellular structures that produce energy in the body.

19 Oct 2017

Penn researchers functionally dissect gene variant linked to FTLD

Seven years ago, Penn Medicine researchers showed that mutations in the TMEM106B gene significantly increased a person's risk of frontotemporal lobar degeneration (FTLD), the second most common cause of dementia in those under 65.

19 Oct 2017

Liver cancers linked to compound popular in herbal remedies

A latest study has shown that Aristolochic Acids (AA) – that are commonly used as a natural product found in some natural remedies, could be associated with liver cancers. Researchers from Singapore and Taiwan showed in their study that AA could be causing mutations in the genes that predispose an individual to liver cancers.

19 Oct 2017

Brazilian researchers find more significant cognitive deficits among early-onset cocaine users

People who begin using cocaine during adolescence display more significant cognitive deficits than people who begin using the drug in adulthood.

18 Oct 2017

Arsenic trioxide could be powerful therapy to extend lives of certain glioblastoma patients

From Sherlock Holmes to Agatha Christie, arsenic is often the poison of choice in popular whodunits. But in ultra-low dosage, and in the right form, this naturally occurring chemical element can be a potent force against cancer.

17 Oct 2017

USC study reveals how schizophrenia has biological effect on the entire brain

Some 40 years since CT scans first revealed abnormalities in the brains of schizophrenia patients, international scientists say the disorder is a systemic disruption to the brain's entire communication system.

17 Oct 2017

Using AFM to study cell mechanics and function

My lab, broadly speaking, is interested in trying to understand interactions between cells and materials. Those could be materials that are present within living tissue or materials that we use for engineering purposes to try to do something of technological or therapeutic interest.

From Bruker Nano Surfaces and Metrology 17 Oct 2017

Scientists validate biomarker indicative of brain cancer patient's prognosis and drug response

Scientists at the Icahn School of Medicine at Mount Sinai, Sema4, and collaborating institutions including Colorado State University and Fred Hutchinson Cancer Center reported results today from a glioblastoma study in which they validated a biomarker indicative of a patient's prognosis and likely response to specific therapies.

16 Oct 2017

Specific regions of silenced DNA help define cell's identity, study suggests

The fundamental mechanisms governing how cells form an identity such as becoming a muscle cell or a nerve cell are not fully understood. Multiple diseases, including cancer, have been linked to cells going down the wrong developmental path during maturation.

13 Oct 2017

Cold Spring Harbor Laboratory Press releases new book on cancer evolution

Cold Spring Harbor Laboratory Press announced the release of Cancer Evolution, available on its website in hardcover and ebook formats.

12 Oct 2017

Brain stimulation is effective way to improve endurance performance, research shows

Research by the University of Kent into the effects of brain stimulation on athletes' performance has demonstrated that it is an effective way to improve endurance.

12 Oct 2017

Dementia patient at center of spoon-feeding controversy dies

An Oregon woman with Alzheimer's disease, whose husband claimed she was kept alive with spoon-feeding against her written wishes, has died.

12 Oct 2017

Study pinpoints racial disparities linked to severity and effects of peripartum cardiomyopathy

African American women were found to be twice as likely to be diagnosed with peripartum cardiomyopathy as compared to women of Caucasian, Hispanic/Latina, Asian, and other ethnic backgrounds, according to a new study--the largest of its kind--published today in JAMA Cardiology by researchers from the Perelman school of Medicine at the University of Pennsylvania.

11 Oct 2017

Study reveals unique norovirus characteristic of hiding from host immune system

Noroviruses are the leading cause of non-bacterial gastroenteritis in the world and are estimated to cause 267 million infections and 20,000 deaths each year. This virus causes severe diarrhea, nausea, and stomach pain.

11 Oct 2017

Medical School News and Research

So much care it hurts: Unneeded scans, therapy, surgery only add to patients’ ills

Systematic review finds lack of data on medical cannabis use in children and adolescents

Research finds decrease in opioid use among patients recovering from hip and knee replacement

Experts create quality improvement blueprint to reduce repetitive lab tests for hospitalized patients

Kidney failure linked to lower quality of life, psychosocial challenges in young adults

Brain-training could help elderly people increase their understanding of words in noisy situations

Study finds mitochondrial DNA damage in Veterans with Gulf War illness

Penn researchers functionally dissect gene variant linked to FTLD

Liver cancers linked to compound popular in herbal remedies

Brazilian researchers find more significant cognitive deficits among early-onset cocaine users

Arsenic trioxide could be powerful therapy to extend lives of certain glioblastoma patients

USC study reveals how schizophrenia has biological effect on the entire brain

Using AFM to study cell mechanics and function

Scientists validate biomarker indicative of brain cancer patient's prognosis and drug response

Specific regions of silenced DNA help define cell's identity, study suggests

Cold Spring Harbor Laboratory Press releases new book on cancer evolution

Brain stimulation is effective way to improve endurance performance, research shows

Dementia patient at center of spoon-feeding controversy dies

Study pinpoints racial disparities linked to severity and effects of peripartum cardiomyopathy

Study reveals unique norovirus characteristic of hiding from host immune system

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

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