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Rember revamped for Phase 3 testing in behavioral-variant frontotemporal dementia

Rember—the blue dye that created a stir in 2008 when Phase 2 clinical trial data claimed that it slowed decline in people with Alzheimer's disease—has now been revamped for Phase 3 testing in another disease, behavioral-variant frontotemporal dementia (bvFTD).

6 Oct 2012

Progress toward preventing initial and recurrent episodes of C. diff infection

Surgeons are making progress toward preventing initial and recurrent episodes of clostridium difficile colitis (C. difficile or C. diff), a vicious bacterial infection that is estimated to affect about 336,000 people each year, typically patients on antibiotics.

6 Oct 2012

UMDNJ postdoctoral researcher receives 2012 NIH Director's Early Independence Award

Mona Batish, PhD, a postdoctoral researcher at the University of Medicine and Dentistry of New Jersey-New Jersey Medical School, is one of 14 scientists nationwide who have received the 2012 National Institutes of Health (NIH) Director's Early Independence Award.

5 Oct 2012

MannKind completes enrollment in AFREZZA Phase 3 clinical studies for type 1 and 2 diabetes

MannKind Corporation today announced that it has completed recruiting patients for two Phase 3 clinical studies of AFREZZA (insulin human [rDNA origin]), an investigational, ultra rapid-acting mealtime insulin therapy, administered using MannKind's to-be-marketed next-generation inhaler.

5 Oct 2012

I COUGH program reduces likelihood of respiratory complications in surgical patients

Respiratory complications—including pneumonia and ventilator dependency—are among the most common complications that occur after operations. But a simple and inexpensive postoperative pulmonary care program known as "I COUGH" reduces the likelihood of those life-threatening and costly complications, researchers from Boston University Medical Center reported today at the 2012 American College of Surgeons (ACS) Annual Clinical Congress.

5 Oct 2012

Botox injections effectively treat urinary urgency incontinence in women

Botox- (onabotulinum toxin-A) injections to the bladder are as effective as medication for treating urinary urgency incontinence in women, but the injection is twice as likely to completely resolve symptoms. These findings were published in the latest issue of The New England Journal of Medicine by a National Institutes of Health clinical trials network including Loyola University Chicago Stritch School of Medicine (SSOM).

5 Oct 2012

UT Austin chair to receive Founders Award from National Academy of Engineering

The National Academy of Engineering has selected Nicholas Peppas as its 2012 Founders Award recipient in recognition of his pioneering work in the areas of polymer chemistry, bioengineering, pharmaceutical sciences and advanced drug delivery.

5 Oct 2012

New gene test can detect pre-cancerous cells in patients with mouth lesions

Researchers from Queen Mary, University of London have developed a new gene test that can detect pre-cancerous cells in patients with benign-looking mouth lesions. The test could potentially allow at-risk patients to receive earlier treatment, significantly improving their chance of survival.

5 Oct 2012

Favorable preliminary results from XenoPort’s XP23829 Phase 1 trial on RRMS, psoriasis

XenoPort, Inc. announced today favorable preliminary results from a Phase 1 clinical trial in healthy adults designed to assess the pharmacokinetics (PK), safety and tolerability of single doses of four different oral formulations of XP23829, a novel fumaric acid ester compound that is a prodrug of monomethyl fumarate (MMF).

5 Oct 2012

Sublingual immunotherapy highly effective for chronic allergy and asthma sufferers

Could it be that those with allergic rhinitis (hay fever) and childhood nasal allergies can finally get a break from their allergies and their allergy shots? Chicago's leading allergy, asthma, and immunology expert, Dr. Brian Rotskoff, who treats a large number of Chicago pediatric allergy patients, is happy to say, "Yes!"

5 Oct 2012

Countering neuroinflammation is indeed a potential therapeutic strategy for Alzheimer's

New research proves the validity of one of the most promising approaches for combating Alzheimer's disease (AD) with medicines that treat not just some of the symptoms, but actually stop or prevent the disease itself, scientists are reporting. The study, in the journal ACS Medicinal Chemistry Letters, also identifies a potential new oral drug that the scientists say could lead the way.

5 Oct 2012

RMHC, UTHealth School of Dentistry partner to bring oral and mobile pediatric care in the Houston area

The University of Texas Health Science Center at Houston (UTHealth) School of Dentistry and Ronald McDonald House Charities of Greater Houston/Galveston, Inc.(RMHC) have joined forces to bring oral, mobile pediatric care to the Houston area.

5 Oct 2012

Age impacts salivary markers of oxidative stress, oral pathology

Age has a significant impact on the variance of salivary markers of oxidative stress, and could shed light on the pathogenesis of oral diseases, report Slovakian researchers.

4 Oct 2012

Antibiotic proved to be Achilles’ heel for some

US clinicians have identified patients at particular risk for Achilles injury while using quinolones.

4 Oct 2012

Estrogen/progesterone treatment started soon after menopause appears safe and effective

Estrogen/progesterone treatment started soon after menopause appears safe and relieves many of the symptoms menopausal women face as well as improving mood and markers of cardiovascular risk, according to a multicenter randomized study presented at the North American Menopause Society (NAMS) Annual Meeting in Orlando, Florida.

4 Oct 2012

Positive data from three Onconova Ex-RAD clinical trials on acute radiation syndrome

Onconova Therapeutics, Inc. today announced positive human safety, tolerability, and pharmacokinetic data from three clinical trials of Ex-RAD (recilisib sodium, ON 01210.Na), a novel radioprotectant being developed as a medical countermeasure for the treatment of acute radiation syndrome (ARS).

4 Oct 2012

New JEBDP series provides updates on evidence-based care in periodontics and implant dentistry

What's the latest, research-supported best practice in periodontal care and implant dentistry? Dental specialists and generalists alike can read about it in the first of a new series from The Journal of Evidence-Based Dental Practice (JEBDP), the foremost publication of information about evidence-based dental practice, published by Elsevier.

4 Oct 2012

Vitamin D3 intake does not reduce incidence or severity of upper respiratory tract infections

Although some data have suggested a possible inverse association between serum vitamin D levels and the incidence of upper respiratory tract infections (colds), participants in a randomized controlled trial who received a monthly dose of 100,000 IUs of vitamin D3 did not have a significantly reduced incidence or severity of colds, according to a study in the October 3 issue of JAMA.

4 Oct 2012

ADA, Wiley partner to publish latest book in ‘Practical Guide Series’

John Wiley & Sons, Inc., recently announced a collaboration with the American Dental Association (ADA) to publish the latest book in their "Practical Guide Series," The ADA Practical Guide to Patients with Medical Conditions.

4 Oct 2012

Roundup: Individual mandate back on Fla. ballot; More Mass. doctors embrace new payment methods; Ga. hospital tax fight rages on

In a bid to remake Florida's judiciary, Republicans are asking voters to oust three state Supreme Court justices and give the Legislature greater power over Supreme Court appointments. ... In Florida, the issue is not same-sex marriage but another politically divisive matter: President Obama's health care law. In a 2010 ruling, the Florida Supreme Court removed from the ballot a nonbinding amendment allowing Floridians to refuse to buy mandatory health insurance.

4 Oct 2012

Oral News and Research

Rember revamped for Phase 3 testing in behavioral-variant frontotemporal dementia

Progress toward preventing initial and recurrent episodes of C. diff infection

UMDNJ postdoctoral researcher receives 2012 NIH Director's Early Independence Award

MannKind completes enrollment in AFREZZA Phase 3 clinical studies for type 1 and 2 diabetes

I COUGH program reduces likelihood of respiratory complications in surgical patients

Botox injections effectively treat urinary urgency incontinence in women

UT Austin chair to receive Founders Award from National Academy of Engineering

New gene test can detect pre-cancerous cells in patients with mouth lesions

Favorable preliminary results from XenoPort’s XP23829 Phase 1 trial on RRMS, psoriasis

Sublingual immunotherapy highly effective for chronic allergy and asthma sufferers

Countering neuroinflammation is indeed a potential therapeutic strategy for Alzheimer's

RMHC, UTHealth School of Dentistry partner to bring oral and mobile pediatric care in the Houston area

Age impacts salivary markers of oxidative stress, oral pathology

Antibiotic proved to be Achilles’ heel for some

Estrogen/progesterone treatment started soon after menopause appears safe and effective

Positive data from three Onconova Ex-RAD clinical trials on acute radiation syndrome

New JEBDP series provides updates on evidence-based care in periodontics and implant dentistry

Vitamin D3 intake does not reduce incidence or severity of upper respiratory tract infections

ADA, Wiley partner to publish latest book in ‘Practical Guide Series’

Roundup: Individual mandate back on Fla. ballot; More Mass. doctors embrace new payment methods; Ga. hospital tax fight rages on

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