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Researchers pinpoint new neural mechanism that regulates chronic stress response

In addition to the classic stress response in our bodies - an acute reaction that gradually abates when the threat passes - our bodies appear to have a separate mechanism that deals only with chronic stress.

15 Feb 2017

Emory researchers reveal 'matchmaker' role for protein linked to SMA

A puzzling question has lurked behind SMA, the leading genetic cause of death in infants. The disorder leads to reduced levels of the SMN protein, which is thought to be involved in processing RNA, something that occurs in every cell in the body.

14 Feb 2017

Review shows lipid nanoparticles as highly promising delivery systems in gene therapy

Lipid nanoparticles (SLNs and NLCs) are regarded as highly promising systems for delivering nucleic acids in gene therapy.

14 Feb 2017

CU Boulder scientists develop brain-based model to predict pain using variables beyond sensory input

Pain is a signal of actual or potential damage to the body, so it is natural to think of it as a localized sensation: knee pain in the knee, back pain in the back and so on.

14 Feb 2017

Non-invasive imaging technique accurately detects skin cancer without surgical biopsy

Researchers funded by the National Institute of Biomedical Imaging and Bioengineering have developed a non-invasive imaging technique that accurately detects skin cancer without surgical biopsy.

13 Feb 2017

TSRI scientists describe how key molecules in the brain work together to trigger intense anxiety

In a new study, researchers at The Scripps Research Institute have described how two important molecules in the brain work together to trigger intense anxiety.

13 Feb 2017

Researchers identify link between neuronal proteins and frontotemporal lobar degeneration

Frontotemporal lobar degeneration is a type of dementia characterized by personality changes, language dysfunction, and abnormal behavior. It has an earlier onset than Alzheimer's disease, and is associated with a buildup of the tau protein in affected nerve cells (neurons).

13 Feb 2017

Scientists discover 'Achilles' heel' of tumor-suppressing protein that drives prostate cancer metastasis

Researchers at Cold Spring Harbor Laboratory have discovered that a protein called Importin-11 protects the anti-cancer protein PTEN from destruction by transporting it into the cell nucleus. A study they publish today in The Journal of Cell Biology suggests that the loss of Importin-11 may destabilize PTEN, leading to the development of lung, prostate, and other cancers.

13 Feb 2017

Researchers use liquid biopsies, tiny experimental device to predict cancer spread and hasten diagnosis

A team of investigators from Cedars-Sinai and UCLA is using a new blood-analysis technique and tiny experimental device to help physicians predict which cancers are likely to spread by identifying and characterizing tumor cells circulating through the blood.

13 Feb 2017

LMU study shows crucial role of microRNAs in protecting precursors of neurons

Programmed cell death is an integral part of embryonic development. Exploring the regulation of the process, Ludwig-Maximilians-Universitaet in Munich researchers have shown that so-called microRNAs protect the precursors of neurons from 'precocious' elimination.

13 Feb 2017

Study sheds light on role of brain region in social behavior and pathology in autism

Researchers at Rosalind Franklin University of Medicine and Science have induced empathy-like behavior by identifying then manipulating a brain circuit in an experimental model, an indication that new strategies may help people with autism spectrum disorder gain social abilities.

8 Feb 2017

Mutated genes lead to tooth enamel defects that increase risk of caries

Bacteria are not the sole cause of caries; tooth resistance also plays an instrumental role. Researchers from the University of Zurich demonstrate that mutated genes lead to defects in the tooth enamel and can therefore encourage the development of caries.

7 Feb 2017

New Caltech study shows how chaperones protect ribosomal proteins

For proteins, this would be the equivalent of the red-carpet treatment: each protein belonging to the complex machinery of ribosomes -- components of the cell that produce proteins -- has its own chaperone to guide it to the right place at the right time and protect it from harm.

3 Feb 2017

Deep brain stimulation can reduce heroin relapse in rat models of addiction, TSRI study shows

Scientists at The Scripps Research Institute have found that deep brain stimulation (DBS) can greatly reduce the compulsion to use heroin in standard rat models of addiction.

2 Feb 2017

Study reveals how white blood cells get pushy to rapidly reach areas of infection

One of the mysteries of the living body is the movement of cells - not just in the blood, but through cellular and other barriers.

31 Jan 2017

Researchers discover earliest-acting protein in C-elegans that plays key role in cell division

Researchers from three U.S. universities have identified, using roundworms, the earliest-acting protein known to duplicate the centriole, a tiny cylinder-shaped structure that is a key component of the machinery that organizes cell division in animals.

31 Jan 2017

Novel potassium channel genes could be promising therapeutic targets for alcohol use disorder

A handful of FDA-approved drugs exist for treating individuals with alcohol use disorder but they have been largely ineffective at reducing the high rates of relapse. As such, there remains a critical need to identify and develop alternative pharmacological treatment options.

31 Jan 2017

Research provides insight into how melanoma and other cancers spread from solid tumors

In a second human case, a Yale-led research team has found that a melanoma cell and a white blood cell can fuse to form a hybrid with the ability to metastasize. The finding provides further insight into how melanoma and other cancers spread from solid tumors with implications for future treatment.

30 Jan 2017

NTNU researcher uses big data to understand how immune system responds to viral attack

An enzyme found in many bacteria, including the bacterium that gives us strep throat, has given mankind a cheap and effective tool with which to edit our own genes.

30 Jan 2017

Antibodies can activate nerve cells within milliseconds, study shows

Antibodies are able to activate human nerve cells within milliseconds and hence modify their function -- that is the surprising conclusion of a study carried out at Human Biology at the Technical University of Munich.

28 Jan 2017

Cell Nucleus News and Research

Researchers pinpoint new neural mechanism that regulates chronic stress response

Emory researchers reveal 'matchmaker' role for protein linked to SMA

Review shows lipid nanoparticles as highly promising delivery systems in gene therapy

CU Boulder scientists develop brain-based model to predict pain using variables beyond sensory input

Non-invasive imaging technique accurately detects skin cancer without surgical biopsy

TSRI scientists describe how key molecules in the brain work together to trigger intense anxiety

Researchers identify link between neuronal proteins and frontotemporal lobar degeneration

Scientists discover 'Achilles' heel' of tumor-suppressing protein that drives prostate cancer metastasis

Researchers use liquid biopsies, tiny experimental device to predict cancer spread and hasten diagnosis

LMU study shows crucial role of microRNAs in protecting precursors of neurons

Study sheds light on role of brain region in social behavior and pathology in autism

Mutated genes lead to tooth enamel defects that increase risk of caries

New Caltech study shows how chaperones protect ribosomal proteins

Deep brain stimulation can reduce heroin relapse in rat models of addiction, TSRI study shows

Study reveals how white blood cells get pushy to rapidly reach areas of infection

Researchers discover earliest-acting protein in C-elegans that plays key role in cell division

Novel potassium channel genes could be promising therapeutic targets for alcohol use disorder

Research provides insight into how melanoma and other cancers spread from solid tumors

NTNU researcher uses big data to understand how immune system responds to viral attack

Antibodies can activate nerve cells within milliseconds, study shows

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