Ribonucleic Acid News and Research

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Evaluating SARS-CoV-2 bivalent booster vaccine against severe COVID-19 outcomes

In a recent study posted to the medRxiv* preprint server, researchers assessed the effectiveness of a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) bivalent booster vaccine against severe SARS-CoV-2 infection outcomes.

9 Mar 2023

Symptomatic COVID-19 is associated with deficits in task-related cognitive function and psychiatric symptoms

Researchers conducted a prospective population survey, functional brain imaging, and a cognitive task performance test to determine whether a history of symptomatic coronavirus disease 2019 (COVID-19) was associated with psychiatric and neurocognitive symptoms.

7 Mar 2023

Effectiveness of monovalent COVID-19 mRNA booster vaccination vs. two-dose primary series during Omicron variant circulation

Researchers estimated the immune protection conferred by monovalent-type COVID-19 mRNA booster doses vs. two-dose prime vaccination series during SARS-CoV-2 Omicron variant predominance in community settings.

7 Mar 2023

Decades of substantial U.S. Government investment in mRNA technology paved way for COVID-19 vaccines

Researchers explore the United States public funding for the development of COVID-19 mRNA vaccines.

6 Mar 2023

Antibody levels from prime COVID-19 mRNA vaccine influences the efficacy of booster doses

Researchers evaluate the response of pre-existing immunity to booster doses of mRNA COVID-19 vaccines.

6 Mar 2023

Zoo study: SARS-CoV-2 surveillance across all mammal species

Researchers from Belgium conduct SARS-CoV-2 surveillance among all mammal species found in two zoos.

6 Mar 2023

Meta-analysis on COVID-19 vaccine effectiveness in association with antibody titers

Researchers performed a meta-analysis analyzing randomized controlled trials (RCTs) that evaluated the effectiveness of coronavirus disease 2019 (COVID-19) vaccines, and the dose-response association of humoral responses with vaccine effectiveness.

6 Mar 2023

Researchers optically evoke tachycardia enhanced anxiety-like behaviour

In a recent study published in the journal Nature, researchers devised a non-invasive optogenetic and wearable cardiac pacemaker for accurate and specific control of cardiac rhythm for ≤900 beats per minute (bpm), enabled by micro-light-emitting display (LED) harness and systemic channelrhodopsin delivery.

6 Mar 2023

Review highlights the effectiveness of diet-based low-density lipoprotein lowering over medication

In a recent article published in the journal Nutrition, researchers in Australia summarized how diet could help decrease low-density lipoprotein cholesterol (LDLc) or triglyceride concentrations in polygenic hypercholesterolemia.

5 Mar 2023

Naked mRNA delivered using needle-free PYRO injection presents a safe and effective potential vaccination method

Researchers examined the vaccination effects and local antigen expression efficiency of a needle-free vaccination technique involving pyro-drive liquid jet injection (PYRO) to deliver the naked messenger ribonucleic acid (mRNA) to the skin.

3 Mar 2023

Multi-organ scRNA-seq reveals targeting pro- or anti-inflammatory regulators may be exploited for personalized treatment of immune diseases

Researchers performed multi-organ single-cell RNA sequencing of collagen-induced arthritis murine model to evaluate immune-mediated inflammatory disease alterations by characterizing the genome, organizing the organome, and prioritizing pathways in the multi-organ data.

3 Mar 2023

Study identifies the essential genetic and immunologic perturbations occurring in patients with long COVID lung fibrosis

Researchers elucidated immunologic and genetic perturbations in long COVID patients with pulmonary fibrosis.

3 Mar 2023

Does the incidence of reported myocarditis or pericarditis after BNT162b2 vaccination vary by age, sex, and inter-dose interval among adolescents aged 12 to 17?

Researchers conducted a population-based cohort study among 12 to 17-year-old adolescents in Ontario, Canada, to estimate the incidence of myocarditis or pericarditis after BNT162b2 vaccination.

3 Mar 2023

Study results provide strong evidence for association of genetic markers to long COVID mappable to fatigue

Researchers analyzed polygenic risk scores in whole genome sequences obtained from blood samples of long COVID patients to determine genomic predictors of long COVID.

2 Mar 2023

SARS-CoV-2 BA.1 and BA.2 breakthrough infections likely protect against BA.4 infection

Omicron BTIs induce durable neutralizing immune responses by recalling cross-reactive and vaccine-induced memory B lymphocytes.

1 Mar 2023

New cell-based assay shown to rapidly profile drug resistance to three widely used SARS-CoV-2 main protease inhibiting drugs

In a recent study posted to the bioRxiv* pre-print server, researchers tested three next-generation severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) main protease (Mpro) inhibitors, namely, nirmatrelvir, ensitrelvir, and FB2001, using a novel cell-based assay.

1 Mar 2023

What is the role of B cells in breast cancer pathology?

In a recent study published in Cancers, researchers comprehensively summarized all available information about B cells in the context of breast cancer.

1 Mar 2023

Evidence that cross-reactive immunity from common human coronaviruses can influence response to SARS-CoV-2

In a recent study published in the journal Vaccines, researchers in Saudi Arabia and the United States examined immune responses and immunoglobulin G (IgG) cross-reactivity in individuals infected with Middle East respiratory syndrome coronavirus (MERS-CoV) and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

28 Feb 2023

Genome editing techniques based on bacterial-artificial-chromosome in herpesvirus research

In a recent study published in the Microorganisms journal, researchers in China reviewed the uses of bacterial-artificial-chromosome (BAC)-based genome editing techniques in herpesvirus research.

28 Feb 2023

A review of respiratory viruses monitored in wastewater samples

Researchers review previous studies discussing the content or respiratory viruses in wastewater samples.

28 Feb 2023

Ribonucleic Acid News and Research

Evaluating SARS-CoV-2 bivalent booster vaccine against severe COVID-19 outcomes

Symptomatic COVID-19 is associated with deficits in task-related cognitive function and psychiatric symptoms

Effectiveness of monovalent COVID-19 mRNA booster vaccination vs. two-dose primary series during Omicron variant circulation

Decades of substantial U.S. Government investment in mRNA technology paved way for COVID-19 vaccines

Antibody levels from prime COVID-19 mRNA vaccine influences the efficacy of booster doses

Zoo study: SARS-CoV-2 surveillance across all mammal species

Meta-analysis on COVID-19 vaccine effectiveness in association with antibody titers

Researchers optically evoke tachycardia enhanced anxiety-like behaviour

Review highlights the effectiveness of diet-based low-density lipoprotein lowering over medication

Naked mRNA delivered using needle-free PYRO injection presents a safe and effective potential vaccination method

Multi-organ scRNA-seq reveals targeting pro- or anti-inflammatory regulators may be exploited for personalized treatment of immune diseases

Study identifies the essential genetic and immunologic perturbations occurring in patients with long COVID lung fibrosis

Does the incidence of reported myocarditis or pericarditis after BNT162b2 vaccination vary by age, sex, and inter-dose interval among adolescents aged 12 to 17?

Study results provide strong evidence for association of genetic markers to long COVID mappable to fatigue

SARS-CoV-2 BA.1 and BA.2 breakthrough infections likely protect against BA.4 infection

New cell-based assay shown to rapidly profile drug resistance to three widely used SARS-CoV-2 main protease inhibiting drugs

What is the role of B cells in breast cancer pathology?

Evidence that cross-reactive immunity from common human coronaviruses can influence response to SARS-CoV-2

Genome editing techniques based on bacterial-artificial-chromosome in herpesvirus research

A review of respiratory viruses monitored in wastewater samples

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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