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Diet, microbial metabolites, and cytokine levels correlate with depression and anxiety symptoms in obese individuals

Researchers determine the association between diet, microbe-derived metabolites, and cytokine levels with anxiety and depression among obese adults.

6 Feb 2023

Ants show the potential to become a fast, efficient, inexpensive, and non-invasive tool for the detection of human tumors

Researchers demonstrated the use of ants as olfactory bio-detectors of human tumors.

31 Jan 2023

A high-throughput screening assay for small molecule inhibitors of the antigen aminopeptidase ERAP1

The January 2023 issue of SLAS Discovery contains a collection of four full-length articles and one technical brief covering cancer research, high-throughput screening (HTS) assay development and other drug discovery exploration.

27 Jan 2023

Study shows improved host health by modulating intestinal microbiota

Researchers presented intestinal microbiota modulation as a probable therapeutic option for diseases such as Crohn’s disease (CD).

26 Jan 2023

Single drop of blood can be used to measure thousands of molecules

Researchers at Stanford Medicine have shown they can measure thousands of molecules — some of which are signals of health — from a single drop of blood.

25 Jan 2023

Novel amyloid protein discovered from canine mammary tumors

A collaboration led by scientists at Tokyo University of Agriculture and Technology (TUAT), Japan, has discovered a novel amyloid protein from canine mammary tumors.

24 Jan 2023

Researchers develop a simple new assay to eliminate heteroresistance in Enterobacter species

Bacteria of the genus Enterobacter are among the most dangerous bacteria associated with hospital infections worldwide.

24 Jan 2023

Powerful microscopy tool sheds light on the origins of arterial biomass in pulmonary arterial hypertension

Pulmonary arterial hypertension (PAH) is a rare and incurable disease of the lung arteries that causes early death.

20 Jan 2023

$3 million NIH grant to support research on Alzheimer's disease

Researchers at the Beckman Institute for Advanced Science and Technology will use a unique combination of imaging techniques to study Alzheimer's disease on a scale that's never been done before.

19 Jan 2023

Overweight people have a different vitamin D metabolism

A new study in JAMA Network Open aimed to determine whether BMI is capable of modifying vitamin D metabolism as well as response to supplementation.

18 Jan 2023

Researchers identify plasma metabolomic markers for the Mediterranean diet among pregnant women

A recent study identifies blood metabolomic markers and metabolite panels linked to the Mediterranean diet in pregnant women.

17 Jan 2023

The loss of epigenetic information accelerates the aging process

A new study in the journal Cell aimed to determine whether epigenetic changes are a cause of mammalian aging.

15 Jan 2023

Valuable tool reveals the connections between gut microbes and the brain

In the past decade, researchers have begun to appreciate the importance of a two-way communication that occurs between microbes in the gastrointestinal tract and the brain, known as the gut–brain axis.

13 Jan 2023

Comprehensive atlas of protein kinases could help scientists decipher many cellular signaling pathways

One of the most important classes of human enzymes are protein kinases - signaling molecules that regulate nearly all cellular activities, including growth, cell division, and metabolism.

12 Jan 2023

Unique mass spectrometry-based approach to study specific changes in DNA after replication

A new method to study specific changes in DNA after replication has been published as a technical report in Nature Cell Biology.

12 Jan 2023

Spike protein mutations in Omicron subvariants increase their susceptibility to reductive cleavage of disulfide bonds

Researchers discovered that the spike protein of SARS-CoV-2 is susceptible to cleavage at the disulfide bonds, and the vulnerability to reductive cleavage varies across variants, with the Omicron variant family being highly susceptible to reduction.

10 Jan 2023

Researchers demonstrate the role of Klotho protein in the formation of osteoarthritis

Researchers in the United States and Japan have discovered a new mechanism that links age-related cartilage tissue stiffening with the repression of a key protein associated with longevity.

10 Jan 2023

Evosep receives strategic investment from Novo Holding A/S to accelerate its effort on clinical proteomics

Evosep today announced that Novo Holdings A/S has become a minority shareholder in Evosep Aps with a US$ 40m investment to further Evosep’s technology and application portfolio for clinical proteomics.

From Evosep 10 Jan 2023

New Bruker-Biognosys collaboration aims to deliver advanced proteomics CRO services

Bruker Corporation and Switzerland-based Biognosys AG today announced a strategic partnership, in which Bruker has made a majority-ownership investment in Biognosys. Financial details were not disclosed. J.P.Morgan acted as exclusive financial advisor to Biognosys.

From Bruker BioSpin Division 10 Jan 2023

Circulating microparticle proteins predict placenta accreta spectrum before delivery

A recent study published in the journal Scientific Reports reported that circulating microparticle (CMP) proteins predict pregnancies complicated by placenta accreta spectrum (PAS).

9 Jan 2023