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Conditions linked to obesity leave the lungs of obese patients more susceptible to COVID-19

Conditions related to obesity, including inflammation and leaky gut, leave the lungs of obese patients more susceptible to COVID-19 and may explain why they are more likely to die from the disease, UTSW scientists say in a new article published online in eLife.

16 Sep 2020

COVID-19 works with the body's microbiota to increase disease severity in obese and diabetic patients

The combined effects of the body's microbiota working together with COVID-19 in the lungs could explain the severity of the disease in people with obesity and diabetes, according to a new article published today in eLife.

15 Sep 2020

Even mild concussions cause severe and long-lasting impairments in the brain

Even mild concussions cause severe and long-lasting impairments in the brain's ability to clean itself of toxins, and this may seed it for Alzheimer's disease, dementia and other neurodegenerative problems, new research from the University of Virginia School of Medicine reveals.

11 Sep 2020

Allergic immune response against bacteria is not pathological but protective

Allergy is one of the most common diseases in Europe, it is estimated that more than 150 million Europeans suffer from recurring allergies and by 2025 this could have increased to half of the entire European population.

9 Sep 2020

Study links brain astrocyte dysfunction to Parkinson’s disease pathology

A new study using induced pluripotent stem cell technology links astrocyte dysfunction to Parkinson’s disease pathology.

8 Sep 2020

Study shows fatty liver disease is a significant risk factor for COVID-19 hospitalization

A recent observational study by US researchers reveals that individuals with non-alcoholic fatty liver disease and steatohepatitis have increased odds of hospitalization due to coronavirus disease (COVID-19); conversely, metabolic surgery was found to be protective against the admission of infected individuals. The study is currently available on the medRxiv* preprint server.

3 Sep 2020

UC San Diego participates in second, massive clinical trial of COVID-19 vaccine

UC San Diego Health will be part of a second, massive clinical trial to assess the safety, efficacy and immunogenicity of a vaccine designed to protect against SARS-CoV-2, the novel coronavirus that causes COVID-19.

2 Sep 2020

Younger cycad seeds pose greater risk for toxicity, study reveals

University of Guam research has revealed that younger cycad seeds pose a greater risk for toxicity when consumed than more mature seeds, bringing the scientific community one step closer to understanding the origins of a neurodegenerative disease prevalent on Guam in World War II and closer to understanding related neurological disorders elsewhere.

31 Aug 2020

Study identifies three clinical course variations in patients with acute decompensated cirrhosis

When the body can no longer compensate the gradual failure of the liver caused by liver cirrhosis, there is a high risk of acute decompensated liver cirrhosis.

27 Aug 2020

Researchers identify three forms of disease progression for acute decompensated liver cirrhosis

When the body can no longer compensate the gradual failure of the liver caused by liver cirrhosis, there is a high risk of acute decompensated liver cirrhosis.

26 Aug 2020

Excessive fructose consumption can result in non-alcoholic fatty liver disease

Excessive consumption of fructose - a sweetener ubiquitous in the American diet - can result in non-alcoholic fatty liver disease (NAFLD), which is comparably abundant in the United States.

24 Aug 2020

A metabolic enzyme shows great potential as target for immunotherapies

The metabolic enzyme IL4I1 (Interleukin-4-Induced-1) promotes the spread of tumor cells and suppresses the immune system.

20 Aug 2020

Study reveals bacteria's secret weapon to evade immune responses

Monash Biomedicine Discovery Institute scientists have discovered a previously unknown method used by bacteria to evade immune responses.

17 Aug 2020

Standardized guidelines for phage therapy can speed up lifesaving treatment

When clinicians resort to phage therapy for patients who don't respond to antibiotics, the patients are usually very ill and time is of the essence. But the average time for labs to produce therapeutic phages is more than a month.

17 Aug 2020

Discoveries point to a new potential treatment approach for fatal childhood brain tumor

Progress against DIPG, a fatal childhood brain tumor, is usually a game of inches. Studies that hint at even small gains are cause for celebration.

13 Aug 2020

UNC researchers uncover new clues in the battle against CF bacteria

Several different kinds of bacteria can cause lung infections in people with cystic fibrosis (CF). Pseudomonas aeruginosa, which can cause pneumonia, typically infects infants or young children and persists for life, while Burkholderia cepacia complex species only infect teenagers and adults.

7 Aug 2020

Researchers use patient-specific tumor organoid to optimize chemotherapy for appendix, colon tumors

A patient-specific tumor organoid model is being used to identify the most effective chemotherapy protocol to treat appendix and colon tumors, a personalized medicine approach that is showing promise.

7 Aug 2020

High concentrations of toxic pollutants were detected in stranded whales, dolphins

A study led by researchers at Florida Atlantic University's Harbor Branch Oceanographic Institute examined toxins in tissue concentrations and pathology data from 83 stranded dolphins and whales along the southeastern coast of the United States from 2012 to 2018.

7 Aug 2020

UArizona researcher aims to deliver statins effectively into the brain of stroke patients

Every year in the United States, about 800,000 people experience a stroke. Many are left with neurological complications such as paralysis on one side of the body, speech and language problems, vision issues, behavioral changes, and memory loss.

6 Aug 2020

Climate change and disruption of ecosystem affect allergies, respiratory disorders

Climate change and disruption of the ecosystem have the potential to profoundly impact the human body. Xue Ming, professor of neurology at Rutgers New Jersey Medical School, who recently published a paper in the International Journal of Environmental Research and Public Health on the effects of climate change on allergies, autoimmunity and the microbiome - the beneficial microorganisms that live on and inside the human body - discusses how the delicate balance of the environment affects conditions such as allergies, autism, and immune disorders.

6 Aug 2020

Toxins News and Research

Conditions linked to obesity leave the lungs of obese patients more susceptible to COVID-19

COVID-19 works with the body's microbiota to increase disease severity in obese and diabetic patients

Even mild concussions cause severe and long-lasting impairments in the brain

Allergic immune response against bacteria is not pathological but protective

Study links brain astrocyte dysfunction to Parkinson’s disease pathology

Study shows fatty liver disease is a significant risk factor for COVID-19 hospitalization

UC San Diego participates in second, massive clinical trial of COVID-19 vaccine

Younger cycad seeds pose greater risk for toxicity, study reveals

Study identifies three clinical course variations in patients with acute decompensated cirrhosis

Researchers identify three forms of disease progression for acute decompensated liver cirrhosis

Excessive fructose consumption can result in non-alcoholic fatty liver disease

A metabolic enzyme shows great potential as target for immunotherapies

Study reveals bacteria's secret weapon to evade immune responses

Standardized guidelines for phage therapy can speed up lifesaving treatment

Discoveries point to a new potential treatment approach for fatal childhood brain tumor

UNC researchers uncover new clues in the battle against CF bacteria

Researchers use patient-specific tumor organoid to optimize chemotherapy for appendix, colon tumors

High concentrations of toxic pollutants were detected in stranded whales, dolphins

UArizona researcher aims to deliver statins effectively into the brain of stroke patients

Climate change and disruption of ecosystem affect allergies, respiratory disorders

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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