Enzyme News and Research

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Triptolide molecule can turn into 'cruise missile' against cancer

More than 20 years ago, a billboard in China piqued the interest of a chemical biologist. It endorsed an extract from the plant known as the “thunder god vine” as an immunosuppressant.

9 Sep 2016

Mathematical model explains molecular events linked to learning and memory formation

A team of researchers has built a mathematical model that describes the molecular events associated with the beginning stage of learning and memory formation in the human brain.

9 Sep 2016

Novel Trojan Horse antibody strategy may target Ebola's Achilles' heel

In research published online today in Science, a team of scientists describe a new therapeutic strategy to target a hidden Achilles' heel shared by all known types of Ebola virus.

8 Sep 2016

New molecular mechanism may explain pain relieving drug’s diverse benefits

Aspirin's ability to reduce the risk of both cardiovascular disease and colon cancer has been a welcome, yet puzzling, attribute of the pain reliever that has been a mainstay in medicine cabinets for more than 100 years.

7 Sep 2016

Enzyme from oral bacteria could be potential therapy for celiac disease

Researchers have isolated an enzyme from bacteria present in human saliva that has potential as a therapy for celiac disease (CD), an autoimmune disorder that causes severe digestive and other health problems among sufferers when they consume gluten.

6 Sep 2016

Overweight kidney cancer patients live longer than normal-weight counterparts, study shows

Obesity almost always increases cancer risk and worsens outcomes, but researchers led by scientists at Dana-Farber Cancer Institute report that overweight patients with advanced kidney cancer had significantly longer survival than those who were normal or underweight.

6 Sep 2016

Researchers describe how genetic mutations cause unnamed neurological disorder

In rare cases -- for instance, among siblings in two families from Pakistan and Oman described in a new study -- children have been born with an unnamed neurological disorder.

6 Sep 2016

DNA-binding protein CHD1 could be potential biomarker for targeted prostate cancer treatment

The loss of CHD1, one of the most frequently mutated genes in prostate tumors, sensitizes human prostate cancer cells to different drugs, including PARP inhibitors.

5 Sep 2016

Research aims to understand how cell designs length, pattern of heparan sulphate chains

Heparan sulphate occurs as carbohydrate chains which are very important for human body cells both for normal foetal development and during the course of various diseases.

2 Sep 2016

Chemists find efficient way to convert organic molecules into new medicines

Opening a broad vista in the search for effective pharmaceuticals, a collaboration of Chinese and U.S. chemists has laid out a highly efficient new method to convert abundant organic molecules into new medicines.

2 Sep 2016

RIT professor receives federal award for research to help combat threat of antibiotic-resistant bacteria

A Rochester Institute of Technology professor has received a federal award for research that could help in the critical battle to develop new drugs to combat the drastic rise in the number of antibiotic-resistant bacteria.

2 Sep 2016

Mayo Clinic offers CDC’s Zika virus screening test

Mayo Clinic will offer the Zika virus antibody test developed by the Centers for Disease Control and Prevention.

1 Sep 2016

ToMMo scientists identify genetic variants affecting enzymatic activities in healthy people

Scientists from Tohoku University's Tohoku Medical Megabank Organization have published research about genetic diversity and metabolome in Scientific Reports.

1 Sep 2016

Researchers reveal novel link between nicotine and inflammation

An Umeå-based team in collaboration with US researchers reveals a new link between nicotine and inflammation.

1 Sep 2016

Whitehead Institute scientists develop novel method for profiling mitochondrial metabolites

Whitehead Institute scientists have developed a method to quickly isolate and systematically measure metabolite concentrations within the cellular organelles known as mitochondria, often referred to as the "powerhouses of the cell."

31 Aug 2016

Researchers identify new gene for type 2 diabetes at well-established genomic location

Gene researchers have used sophisticated scientific tools to reveal a new gene for type 2 diabetes at a well-established genomic location.

31 Aug 2016

Multi-purpose protein may offer clues for successful treatment of Alzheimer's disease

The tidal wave approaches. In the coming decades, Alzheimer's disease is projected to exact a devastating economic and emotional toll on society, with patient numbers in the US alone expected to reach 13.5 million by mid-century at a projected cost of over a trillion dollars.

30 Aug 2016

Experimental drug may become key tool to target triple-negative breast cancer with immunotherapy

Previous studies at the University of Colorado Cancer Center show that the experimental drug AMPI-109 potently kills triple-negative breast cancer cells.

30 Aug 2016

Selective manipulation of enzyme can stop cancer cachexia

Healthy fat tissue is essential for extended survival in the event of tumor-induced wasting syndrome (cachexia). In Nature Medicine, researchers at Helmholtz Zentrum München show that selective manipulation of an enzyme can stop unwanted metabolic processes.

30 Aug 2016

Deficiency in important enzyme leads to alcohol dependency

A research group under the leadership of Linköping University Professor Markus Heilig has identified an enzyme whose production is turned off in nerve cells of the frontal lobe when alcohol dependence develops.

30 Aug 2016

Enzyme News and Research

Triptolide molecule can turn into 'cruise missile' against cancer

Mathematical model explains molecular events linked to learning and memory formation

Novel Trojan Horse antibody strategy may target Ebola's Achilles' heel

New molecular mechanism may explain pain relieving drug’s diverse benefits

Enzyme from oral bacteria could be potential therapy for celiac disease

Overweight kidney cancer patients live longer than normal-weight counterparts, study shows

Researchers describe how genetic mutations cause unnamed neurological disorder

DNA-binding protein CHD1 could be potential biomarker for targeted prostate cancer treatment

Research aims to understand how cell designs length, pattern of heparan sulphate chains

Chemists find efficient way to convert organic molecules into new medicines

RIT professor receives federal award for research to help combat threat of antibiotic-resistant bacteria

Mayo Clinic offers CDC’s Zika virus screening test

ToMMo scientists identify genetic variants affecting enzymatic activities in healthy people

Researchers reveal novel link between nicotine and inflammation

Whitehead Institute scientists develop novel method for profiling mitochondrial metabolites

Researchers identify new gene for type 2 diabetes at well-established genomic location

Multi-purpose protein may offer clues for successful treatment of Alzheimer's disease

Experimental drug may become key tool to target triple-negative breast cancer with immunotherapy

Selective manipulation of enzyme can stop cancer cachexia

Deficiency in important enzyme leads to alcohol dependency

Biochemical Assays for Efficient Hit Prioritization After Screening eBook

Latest eBooks

Industry Focus eBook - Analytical Chemistry (3rd edition)

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

Advancing degrader and proximity-based drug development

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo