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An effective solution to improve visualization of the cervix during pelvic exams

Pelvic exams are an indispensable part of gynecological care and are used to screen for conditions, such as cervical cancer, that affect millions of patients every year.

14 Nov 2023

Circular extrachromosomal DNA identified as a potential target for new medulloblastoma therapies

A study of newly created databases of medulloblastoma has found that patients with tumors containing circular extrachromosomal DNA - loops of DNA found outside of regular chromosomes - are twice as likely to relapse and three times as likely to die within five years of diagnosis.

14 Nov 2023

New triage system for pregnant women and new mothers improves patient outcomes

Increased vigilance for high blood pressure and diffuse stomach pain. These are some of the characteristics of emergency care adapted for pregnant women and new mothers.

14 Nov 2023

Bioengineered human heart muscle cells and micro-tissues take flight to space

Mount Sinai's Cardiovascular Research Institute is sending bioengineered human heart muscle cells and micro-tissues into space for the first time on NASA's 29th SpaceX commercial resupply services mission, which launched Thursday, November 9.

14 Nov 2023

COVID-19 triggers epigenetic alterations that drive lung damage and fatalities

The COVID-19 disease, due to infection with the SARS-CoV2 virus, became an international pandemic in 2020. To date, more than 770 million people have suffered from the disease and nearly 7 million of them have lost their life.

14 Nov 2023

Traffic emissions disrupt gene expression in human olfactory cells

Exposure to ultrafine particles from traffic alters the expression of many genes in human olfactory mucosa cells, a new study shows.

14 Nov 2023

High-dose CBD fails to relieve pain in knee osteoarthritis patients

Cannabidiol (CBD) is marketed by some suppliers as a painkiller, e.g. for osteoarthritis of the knee. Animal experiments have shown that the substance, which is extracted from the hemp plant, has an anti-inflammatory and pain-relieving effect in arthritis.

14 Nov 2023

Self-perception of health influences physical activity levels in older adults with arthritis

People with arthritis who report more negative feelings about how they are aging tend to get less physical activity and perceive themselves as less healthy, according to a new study by researchers at Hospital for Special Surgery (HSS) and Weill Cornell Medicine.

14 Nov 2023

Novel mechanism of maternal-fetal communication discovered

A research group from the University of Oulu, Finland, has shown that nanoparticles originating from maternal gut bacteria are present in amniotic fluid.

14 Nov 2023

Genetic test for antidepressants could save millions and improve patient outcomes

A special kind of genetic test that helps determine the best antidepressant for patients with moderate-to-severe depression could generate substantive health system savings and greatly improve patient outcomes, according to new research from the University of British Columbia.

14 Nov 2023

Men feel less pain when inflicted by women, study finds

A man who is exposed to physical pain feels less severe pain if he is subjected to pain by a woman compared with a man, according to new research from Lund University in Sweden. In addition, men experience less pain after surgery when asked about it by a woman than by a man.

14 Nov 2023

Adult children discuss the trials of caring for their aging parents

I am 39 years old. I had to care for my father, who passed from cancer in 2019; my mother, who passed in November 2021 from cancer; and since my mother's passing, I have inherited the care of my grandmother.

14 Nov 2023

Facing financial ruin as costs soar for elder care

Margaret Newcomb, 69, a retired French teacher, is desperately trying to protect her retirement savings by caring for her 82-year-old husband, who has severe dementia, at home in Seattle.

14 Nov 2023

New study identifies 4,749 key gene clusters that influence progression of 32 cancer types

Researchers at the Mount Sinai Center for Transformative Disease Modeling have released a groundbreaking study identifying 4,749 key gene clusters, termed "prognostic modules," that significantly influence the progression of 32 different types of cancer.

13 Nov 2023

New gel delivery system overcomes challenges of intratumoral cancer immunotherapy

Intratumoral therapy – in which cancer drugs are injected directly into tumors – is a promising treatment option for solid cancers but has shown limited success in clinical trials due to an inability to precisely deliver the drug and because most immunotherapies quickly dissipate from the site of injection.

13 Nov 2023

Acupuncture may offer limited relief from chronic spontaneous urticaria, study finds

A randomized controlled trial that included more than 300 people diagnosed with chronic spontaneous urticaria (CSU), or hives, found that acupuncture may offer limited relief from the condition, but clinical significance of this finding was unclear.

13 Nov 2023

Study observes virologic rebound in 20% of COVID-19 patients treated with nirmatrelvir-ritonavir

An observational study of patients being treated for acute COVID-19 in a multicenter health care system observed virologic rebound in about 20 percent of patients treated with nirmatrelvir-ritonavir (N-R) versus about 2 percent of those who did not receive treatment. The findings are published in Annals of Internal Medicine.

13 Nov 2023

Automated referrals to pharmacy services dramatically increase appropriate statin prescription rates

The odds of prescribing the appropriate dose of statins - a medicine used to lower "bad" cholesterol levels - increased sixfold when automated referrals were made to pharmacy services, instead of relying on traditional prescribing methods, according to researchers at the Perelman School of Medicine at the University of Pennsylvania.

13 Nov 2023

One in five individuals taking nirmatrelvir-ritonavir therapy found to experience rebound COVID

A new study by investigators from Mass General Brigham found that one in five individuals taking Nirmatrelvir-ritonavir therapy, commonly known as Paxlovid, to treat severe symptoms of COVID-19, experienced a positive test result and shedding of live and potentially contagious virus following an initial recovery and negative test - a phenomenon known as virologic rebound.

13 Nov 2023

Hospital-acquired COVID-19 mortality drops in Omicron era post-vaccination, reveals Swedish study

In a study published in JAMA Network Open, researchers found that hospital-acquired SARS-CoV-2 infections in Stockholm led to increased 30-day mortality in the pre-vaccination period but showed significantly lower mortality during the Omicron wave post-vaccination. The study underscores the importance of vaccination in reducing mortality risks from nosocomial SARS-CoV-2 infections.

13 Nov 2023

Hospital News and Research

An effective solution to improve visualization of the cervix during pelvic exams

Circular extrachromosomal DNA identified as a potential target for new medulloblastoma therapies

New triage system for pregnant women and new mothers improves patient outcomes

Bioengineered human heart muscle cells and micro-tissues take flight to space

COVID-19 triggers epigenetic alterations that drive lung damage and fatalities

Traffic emissions disrupt gene expression in human olfactory cells

High-dose CBD fails to relieve pain in knee osteoarthritis patients

Self-perception of health influences physical activity levels in older adults with arthritis

Novel mechanism of maternal-fetal communication discovered

Genetic test for antidepressants could save millions and improve patient outcomes

Men feel less pain when inflicted by women, study finds

Adult children discuss the trials of caring for their aging parents

Facing financial ruin as costs soar for elder care

New study identifies 4,749 key gene clusters that influence progression of 32 cancer types

New gel delivery system overcomes challenges of intratumoral cancer immunotherapy

Acupuncture may offer limited relief from chronic spontaneous urticaria, study finds

Study observes virologic rebound in 20% of COVID-19 patients treated with nirmatrelvir-ritonavir

Automated referrals to pharmacy services dramatically increase appropriate statin prescription rates

One in five individuals taking nirmatrelvir-ritonavir therapy found to experience rebound COVID

Hospital-acquired COVID-19 mortality drops in Omicron era post-vaccination, reveals Swedish study

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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