Kidney News and Research

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BRI receives grant to lead ITN for evaluating novel therapies for transplantation, allergy and autoimmune diseases

The National Institutes of Health has awarded Benaroya Research Institute at Virginia Mason a 7-year grant to lead the Immune Tolerance Network.

24 Jan 2014

CWRU researchers receive NIAID grant to conduct HIV research and clinical trials

AIDS researchers from Case Western Reserve University and University Hospitals Case Medical Center have received a seven-year funding award from the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health.

23 Jan 2014

High-protein diet increases chance of developing kidney stones, other renal diseases

High-protein diets, like the popular Dr. Dukan diet, increase the long-term risk of developing kidney disease and have a negative effect on renal urinary and morphological markers. What's more, they may promote serious pathologies like nephrolithiasis (calcium kidney stones) because they drastically reduce urinary citrate (an inhibitor of calcium salt crystallization) and urinary pH, and increase urinary calcium (to compensate for the metabolic acidity caused by excess protein).

22 Jan 2014

Advanced melanoma treatments: an interview with Dr. James Larkin, Consultant Medical Oncologist, The Royal Marsden

Advanced melanoma affects around 2,000 people per year in the UK. Advanced melanoma describes a melanoma that has spread from its site of origin to other areas of the body.

22 Jan 2014

Study: High-protein diet increases chance of developing kidney stones and other renal diseases

An experiment by scientists at the University of Granada, Spain, shows a high-protein diet increases the chance of developing kidney stones and other renal diseases.

22 Jan 2014

Alexion's Soliris gets FDA orphan drug designation for DGF prevention in renal transplant patients

Alexion Pharmaceuticals today announced that the U.S. Food and Drug Administration has granted an orphan drug designation to Soliris (eculizumab), a first-in-class terminal complement inhibitor, for the prevention of delayed graft function in renal transplant patients.

21 Jan 2014

New, "designer" dietary fiber may eliminate side effects of current IBS treatment

A newly-developed, "designer" dietary fiber with an added potential prebiotic effect may eliminate the side effects of current treatment for Irritable Bowel Syndrome which affects 10-20 percent of the population, disproportionately women.

20 Jan 2014

New discovery has potential to transform heart attack treatments

An Australian discovery has the potential to transform the treatment of a heart attack, after a new approach boosted heart function and reduced heart scarring in preclinical studies.

16 Jan 2014

Scientists develop novel treatment for Hairy Cell Leukaemia using drug administered to combat skin cancer

A team of scientists from the University of Leicester has demonstrated a novel treatment for Hairy Cell Leukaemia (HCL), a rare type of blood cancer, using a drug administered to combat skin cancer.

16 Jan 2014

New way to improve lipid profiles in patients undergoing hemodialysis may prevent heart attack

Researchers at Wayne State University have discovered a potential way to improve the lipid profiles in patients undergoing hemodialysis that may prevent cardiovascular disease common in these patients.

16 Jan 2014

CU researcher awarded NIH grant to study benefit of allopurino drug in lowering uric acid levels

Kidney disease poses one of the greatest burdens for people living with type 1 diabetes. A study newly awarded by the National Institutes of Health will look at whether lowering uric acid levels can prevent people with type 1 diabetes from needing hemodialysis or kidney transplant.

15 Jan 2014

New study examines factors that may lead to end stage renal disease

About 33 percent of people with type 2 diabetes suffer kidney damage that progresses to end stage renal disease, at which point they require either dialysis or kidney transplantation. Scientists have thought that this kidney disease is driven by damage to the glomeruli, blood vessels in the kidney, which spill the protein albumin into the urine. Current treatments targeting the resulting "albuminuria" do not prevent kidney failure.

15 Jan 2014

Research reveals new therapy for preventing production of sphingolipids by lymphoma cells

Christopher Parsons, MD, Director of the HIV Malignancies Program at LSU Health Sciences Center New Orleans, is the senior author of a paper that is the first to report that specialized fat (lipid) molecules, called sphingolipids, play a key role in the survival of aggressive lymphomas caused by viruses.

15 Jan 2014

MRI method to map creatine in heart may help detect disorders earlier than traditional methods

A new MRI method to map creatine at higher resolutions in the heart may help clinicians and scientists find abnormalities and disorders earlier than traditional diagnostic methods, researchers at the Perelman School of Medicine at the University of Pennsylvania suggest in a new study published online today in Nature Medicine.

13 Jan 2014

University of Washington develops new device to move kidney stones inside body

Almost one in 10 people will someday experience a kidney stone, which creates what is described as the most intense pain imaginable. This increasingly common condition leads to hundreds of thousands of surgeries in the United States each year.

13 Jan 2014

Research: SLPI protein produced by body in response to injury plays vital role in patients with ALF

Findings published in the American Association for the Study of Liver Diseases journal, Hepatology, indicate that infection, the commonest cause of mortality in patients with acute liver failure, may be decreased by inhibiting the activity of a protein found in saliva called SLPI.

10 Jan 2014

Mylan announces launch of Mycophenolic Acid Delayed-release Tablets

Mylan Inc. today announced that its U.S.-based subsidiary Mylan Pharmaceuticals Inc. has launched Mycophenolic Acid Delayed-release Tablets, 180 mg and 360 mg. This product is the generic version of Novartis' Myfortic Delayed-release Tablets.

9 Jan 2014

Immune tolerance to grafts of muscle, bone and skin could free recipients from lifelong immunosuppression

Massachusetts General Hospital investigators have made an important step towards greater availability of hand transplants, face transplants and other transplants involving multiple types of tissue.

9 Jan 2014

Proteon's PRT-201 gets orphan drug designation for prevention of arteriovenous access dysfunction

Proteon Therapeutics, Inc., a privately held biopharmaceutical company developing novel, first-in-class pharmaceuticals to address the critical medical needs of patients with kidney and vascular diseases, today announced that its lead product, PRT-201, has received orphan drug designation in the European Union for the prevention of arteriovenous access dysfunction in hemodialysis patients.

9 Jan 2014

OxThera announces initiation of Oxabact clinical study in Primary Hyperoxaluria

OxThera AB, a Stockholm-based privately-held biopharmaceutical company, today announced that it has initiated a clinical study in Primary Hyperoxaluria. This announcement bolsters the Company's position as a leader in developing therapies for hyperoxaluria, a debilitating condition that, if untreated, leads to kidney damage and end-stage renal disease.

8 Jan 2014

Kidney News and Research

BRI receives grant to lead ITN for evaluating novel therapies for transplantation, allergy and autoimmune diseases

CWRU researchers receive NIAID grant to conduct HIV research and clinical trials

High-protein diet increases chance of developing kidney stones, other renal diseases

Advanced melanoma treatments: an interview with Dr. James Larkin, Consultant Medical Oncologist, The Royal Marsden

Study: High-protein diet increases chance of developing kidney stones and other renal diseases

Alexion's Soliris gets FDA orphan drug designation for DGF prevention in renal transplant patients

New, "designer" dietary fiber may eliminate side effects of current IBS treatment

New discovery has potential to transform heart attack treatments

Scientists develop novel treatment for Hairy Cell Leukaemia using drug administered to combat skin cancer

New way to improve lipid profiles in patients undergoing hemodialysis may prevent heart attack

CU researcher awarded NIH grant to study benefit of allopurino drug in lowering uric acid levels

New study examines factors that may lead to end stage renal disease

Research reveals new therapy for preventing production of sphingolipids by lymphoma cells

MRI method to map creatine in heart may help detect disorders earlier than traditional methods

University of Washington develops new device to move kidney stones inside body

Research: SLPI protein produced by body in response to injury plays vital role in patients with ALF

Mylan announces launch of Mycophenolic Acid Delayed-release Tablets

Immune tolerance to grafts of muscle, bone and skin could free recipients from lifelong immunosuppression

Proteon's PRT-201 gets orphan drug designation for prevention of arteriovenous access dysfunction

OxThera announces initiation of Oxabact clinical study in Primary Hyperoxaluria

Free guide - Everything about renal proximal tubule cells eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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