Liver News and Research

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RBHS Chancellor leads study to eliminate chronic viral hepatitis

Chronic viral hepatitis has a reputation for being a silent killer. The infection often goes undetected until the symptoms of advanced liver cancer appear. By that point, a patient has a five-year survival rate, according to the American Cancer Society.

17 Dec 2015

Bile acid may help treat fatty liver disease and obesity

A bile acid that can turn off a receptor in the gut has prevented and reversed fatty liver disease in mice, according to an international team of researchers. The compound may help treat certain metabolic disorders, such as Type 2 diabetes and obesity, as well.

16 Dec 2015

Prophylaxis treatment can protect children who receive liver transplants from HBV-infected donors

Researchers have found that a prophylaxis treatment can prevent new-onset hepatitis B in children who receive liver transplants from donors who were previously infected with hepatitis B virus (HBV) but had successfully cleared the virus.

16 Dec 2015

Liver protein aids in accelerating growth of insulin-producing pancreatic 'beta' cells

More than a quarter of the 30 million people with diabetes in the United States depend on daily injections of insulin to maintain their blood glucose levels in a healthy range. Scientists are investigating many techniques to help treat or potentially even cure many of these patients by increasing the body's own insulin-producing pancreatic "beta" cells.

15 Dec 2015

Stanford researchers develop novel technique for mapping diversity of gut bacteria

A collaboration between computer scientists and geneticists at Stanford University has produced a novel technique for mapping the diversity of bacteria living in the human gut.

15 Dec 2015

Researchers discover new way for early detection of potentially deadly fungal infection in leukemia patients

A team of researchers have discovered a new way for early detection of a potentially deadly fungal infection in patients with suppressed immune systems such as those being treated for leukemia or have had an organ transplant.

15 Dec 2015

SLU scientist awarded new $2.2 million NIH grant to develop cure for hepatitis B

With proof-of-principle in his pocket and a new $2.2 million grant from the National Institutes of Health, SLU scientist John Tavis, Ph.D., will take his 25 year mission to finally develop a cure for the hepatitis B virus into the next phase.

15 Dec 2015

Cancer rates rise in many low-and middle-income countries

Improved screening and detection efforts, combined with decreases in risk factors like smoking, have reduced the incidence and mortality rates from several common types of cancer in many high-income countries. However, many low-and middle-income countries have seen cancer rates rise, partially due to increases in risk factors that are typical of Western countries.

14 Dec 2015

Study offers insight into how female Viagra affects the brain

As the drug touted as "the female Viagra" comes to market, researchers at the University of Wisconsin-Madison are learning more about how the drug, called flibanserin, affects the brain.

13 Dec 2015

New MSK-led studies on liquid biopsy presented at San Antonio Breast Cancer Symposium

Information gleaned from a liquid biopsy may help predict how individual women with advanced breast cancer will respond to certain therapies as well as reveal genetic mutations that can impact prognosis, according to two new studies led by Memorial Sloan Kettering Cancer Center Physician-in-Chief José Baselga and physician-scientist Sarat Chandarlapaty.

12 Dec 2015

New therapeutic target can prevent abnormal blood vessel growth that causes gastrointestinal bleeding

A study by IRB Barcelona and IDIBAPS reveals a therapeutic target to prevent the development of the many abnormal blood vessels that cause gastrointestinal bleeding—the main complication in cirrhosis.

12 Dec 2015

Abbott, UCSF identify human pegivirus 2 among some patients with hepatitis C

Abbott and University of California San Francisco published research identifying a newly discovered human virus, known as human pegivirus 2 (HPgV-2), and proving it is found among some patients with hepatitis C (HCV).

12 Dec 2015

Alecensa (alectinib) approved for treatment of people with advanced ALK-positive NSCLC

The U.S. Food and Drug Administration today approved Alecensa (alectinib) to treat people with advanced (metastatic) ALK-positive non-small cell lung cancer (NSCLC) whose disease has worsened after, or who could not tolerate treatment with, another therapy called Xalkori (crizotinib).

11 Dec 2015

PET-MRI combination may change management of high-risk cancer patients

PET/CT and whole-body MRI detect extraskeletal disease that may change the management of high-risk breast and prostate cancer patients, according to a recent study reported in the December issue of The Journal of Nuclear Medicine.

11 Dec 2015

Kanuma approved as first treatment for patients with LAL deficiency

Today, the U.S. Food and Drug Administration approved Kanuma (sebelipase alfa) as the first treatment for patients with a rare disease known as lysosomal acid lipase (LAL) deficiency.

8 Dec 2015

Researchers discover 'triple attack' technique to target liver cancer tumors

In an interdisciplinary collaboration between prominent academic and industry investigators, researchers have discovered a novel method for repositioning an FDA-approved anti-cancer compound so it can specifically target liver cancer tumors. A 'triple attack' technique combining chemotherapy, thermal ablation, and hyperthermia provided a highly targeted, yet minimally invasive approach.

8 Dec 2015

Quest Diagnostics performs RNA testing on patient specimens to detect more cases of HCV

In its commitment to provide diagnostic insights that enhance patient care and outcomes, Quest Diagnostics will automatically perform molecular testing on all patient specimens whose antibody screening results indicate hepatitis C virus infection, and remove standalone positive antibody screening as a test option.

From Quest Diagnostics 8 Dec 2015

Study reveals how MGCs dispose waste that obstructs normal physiological processes

If rubbish is too big and unwieldy for normal household waste, its removal becomes the job of specialized experts. Researchers from the Technical University of Munich (TUM) have now discovered, in cooperation with colleagues from the UK, how large, fused cells help our body to deal with bulky items that may otherwise obstruct normal physiological processes.

7 Dec 2015

World Hepatitis Alliance highlights need to recognise impact of coinfection between HIV and viral hepatitis

Viral hepatitis is one of the leading causes of non-AIDS-related deaths among people living with HIV, yet often goes undiagnosed. Similar to HIV, the hepatitis B and hepatitis C viruses are blood-borne, having similar transmission routes like sexual contact for hepatitis B and injection drug use and sexual contact for hepatitis C.

7 Dec 2015

Experimental gene therapy may improve health outcomes for patients with some forms of blood disorders

New research adds to a growing body of evidence that gene therapy, an experimental technique that involves correcting or replacing a person's mutated or malfunctioning genes, may improve health outcomes for patients with inherited bleeding and immune disorders as well as some forms of blood cancer.

7 Dec 2015

Liver News and Research

RBHS Chancellor leads study to eliminate chronic viral hepatitis

Bile acid may help treat fatty liver disease and obesity

Prophylaxis treatment can protect children who receive liver transplants from HBV-infected donors

Liver protein aids in accelerating growth of insulin-producing pancreatic 'beta' cells

Stanford researchers develop novel technique for mapping diversity of gut bacteria

Researchers discover new way for early detection of potentially deadly fungal infection in leukemia patients

SLU scientist awarded new $2.2 million NIH grant to develop cure for hepatitis B

Cancer rates rise in many low-and middle-income countries

Study offers insight into how female Viagra affects the brain

New MSK-led studies on liquid biopsy presented at San Antonio Breast Cancer Symposium

New therapeutic target can prevent abnormal blood vessel growth that causes gastrointestinal bleeding

Abbott, UCSF identify human pegivirus 2 among some patients with hepatitis C

Alecensa (alectinib) approved for treatment of people with advanced ALK-positive NSCLC

PET-MRI combination may change management of high-risk cancer patients

Kanuma approved as first treatment for patients with LAL deficiency

Researchers discover 'triple attack' technique to target liver cancer tumors

Quest Diagnostics performs RNA testing on patient specimens to detect more cases of HCV

Study reveals how MGCs dispose waste that obstructs normal physiological processes

World Hepatitis Alliance highlights need to recognise impact of coinfection between HIV and viral hepatitis

Experimental gene therapy may improve health outcomes for patients with some forms of blood disorders

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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