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Researchers identify mutation in ITGA10 gene that causes chondrodysplasia in dog breeds

Professor Hannes Lohi's research group at the University of Helsinki and Folkhälsan Research Center has identified a mutation in ITGA10 gene, causing chondrodysplasia in two dog breeds, the Norwegian Elkhound and the Karelian Bear Dog.

26 Sep 2013

Soligenix awarded $6.4M contract to advance preclinical development of OrbeShield for GI ARS

Soligenix, Inc., a clinical stage biopharmaceutical company focused on developing products to treat inflammatory diseases and biodefense medical countermeasures where there remains an unmet medical need, announced today that it has been awarded a contract valued at up to $6.4 million by the US Department of Health and Human Service's National Institutes of Health (specifically funded by the National Institute of Allergy and Infectious Diseases or NIAID).

25 Sep 2013

$Repeating BMD tests after four years provides no clinical benefit of fracture risk in older adults$

Repeating BMD tests after four years provides no clinical benefit of fracture risk in older adults

Repeating bone mineral density (BMD) tests after four years provides little clinical benefit when assessing bone fracture risk in seniors age 75 and older, according to a recent study led by researchers at the Harvard Medical School-affiliated Institute for Aging Research at Hebrew SeniorLife. The study appears in the Sept. 25 online issue of JAMA.

25 Sep 2013

MacLean Center receives Cornerstone Award for outstanding contributions in field of bioethics

The University of Chicago Medicine's MacLean Center for Clinical Medical Ethics has been awarded the prestigious Cornerstone Award from the American Society of Bioethics and Humanities for "outstanding contributions from an institution that has helped shape the direction of the fields of bioethics and/or medical humanities."

25 Sep 2013

$Researchers show link between FTO gene and hip fracture in women$

Researchers show link between FTO gene and hip fracture in women

Australian researchers have demonstrated a strong association between the FTO (fat and obesity) gene and hip fracture in women. While the gene is already well known to affect diabetes and obesity, this is the first study to show that its high-risk variant can increase the risk of hip fracture by as much as 82%.

25 Sep 2013

Metastatic site impacts survival in targeted RCC treatment

Bone and liver metastases may have the heaviest impact on the survival of patients receiving targeted therapy for metastatic renal cell carcinoma, suggest data from the International Metastatic Renal Cell Carcinoma Database Consortium.

24 Sep 2013

NCI Funds Development Of Chrysalis’ Brain Tissue Damage Treatment

The National Cancer Institute awarded Chrysalis BioTherapeutics a $1.5 million contract to continue development of Chrysalin® to mitigate radiotherapy-induced damage to normal brain tissue. The project is a collaboration between Chrysalis, Baylor College of Medicine, and the University of Texas Medical Branch (UTMB).

24 Sep 2013

Dental caries show ‘unexpected’ relationship with head and neck cancer

People with dental caries have a reduced risk for developing head and neck squamous cell carcinoma, a large case-control study has found.

24 Sep 2013

Study suggests certain pediatric surgeries carry low risk of serious blood loss

Certain pediatric surgeries carry such low risk of serious blood loss that clinicians can safely forgo expensive blood typing and blood stocking before such procedures, suggest the results of a small study by researchers at the Johns Hopkins Children's Center.

24 Sep 2013

Researchers reveals key role for stem cells that promote inflammation in atherosclerosis

University at Buffalo translational researchers are developing a richer understanding of atherosclerosis in humans, revealing a key role for stem cells that promote inflammation.

24 Sep 2013

QoL questionnaire predicts nocturia, risk for falling

A study of Japanese outpatients highlights the association between nighttime voiding and bone fractures, after showing that the Nocturia Quality-of-Life questionnaire can identify patients at risk for both.

23 Sep 2013

FDA approves STELARA (Ustekinumab) for treatment of active psoriatic arthritis

Janssen Biotech, Inc., announced today that the U.S. Food and Drug Administration (FDA) has approved STELARA® (ustekinumab) alone or in combination with methotrexate for the treatment of adult patients (18 years or older) with active psoriatic arthritis.

23 Sep 2013

Falls are the leading cause of injuries in older populations

One of the top reasons for trauma admission at Vanderbilt University Medical Center may come as a surprise: falls.

23 Sep 2013

MIT researchers develop microfluidic device that mimics flow of cancer cells through blood vessels

Cancer cells metastasize in several stages -- first by invading surrounding tissue, then by infiltrating and spreading via the circulatory system. Some circulating cells work their way out of the vascular network, eventually forming a secondary tumor.

21 Sep 2013

Applied Integrin Sciences' drug candidate eliminates ovarian cancer tumors in pre-clinical study

Applied Integrin Sciences, Inc. announced today that its first cancer therapeutic drug candidate eliminated all intraperitoneal ovarian cancer tumors in a pre-clinical study testing a novel treatment regimen.

21 Sep 2013

CHMP recommends approval of Xofigo for CRPC, symptomatic bone and visceral metastases

Bayer HealthCare announced today that the the European Committee for Medicinal Products for Human Use recommended Xofigo (radium Ra 223 dichloride) for approval with a proposed indication for the treatment of adults with castration-resistant prostate cancer, symptomatic bone metastases and no known visceral metastases.

20 Sep 2013

Older adults who gain little weight live longer

Some overweight older adults don't need to lose weight to extend their lives, but they could risk an earlier death if they pack on more pounds.

20 Sep 2013

Intentional weight loss can have positive health benefits in older adults

The medical community touts the importance of not carrying excess weight, but that has not always been the message delivered to older adults.

20 Sep 2013

Innovative system can help manipulate stem cells to repair damaged tissues and organs

Scientists know that physical and biochemical signals can guide cells to make, for example, muscle, blood vessels or bone. But the exact recipes to produce the desired tissues have proved elusive.

19 Sep 2013

Researchers develop absorbable implants to promote bone healing

Researchers from Graz University of Technology, together with colleagues from the Medical University of Graz, Vienna University of Technology and the University of Natural Resources and Life Sciences, Vienna, have managed to develop absorbable implants to promote bone healing which are broken down by the body.

19 Sep 2013

Bone News and Research

Researchers identify mutation in ITGA10 gene that causes chondrodysplasia in dog breeds

Soligenix awarded $6.4M contract to advance preclinical development of OrbeShield for GI ARS

Repeating BMD tests after four years provides no clinical benefit of fracture risk in older adults

MacLean Center receives Cornerstone Award for outstanding contributions in field of bioethics

Researchers show link between FTO gene and hip fracture in women

Metastatic site impacts survival in targeted RCC treatment

NCI Funds Development Of Chrysalis’ Brain Tissue Damage Treatment

Dental caries show ‘unexpected’ relationship with head and neck cancer

Study suggests certain pediatric surgeries carry low risk of serious blood loss

Researchers reveals key role for stem cells that promote inflammation in atherosclerosis

QoL questionnaire predicts nocturia, risk for falling

FDA approves STELARA (Ustekinumab) for treatment of active psoriatic arthritis

Falls are the leading cause of injuries in older populations

MIT researchers develop microfluidic device that mimics flow of cancer cells through blood vessels

Applied Integrin Sciences' drug candidate eliminates ovarian cancer tumors in pre-clinical study

CHMP recommends approval of Xofigo for CRPC, symptomatic bone and visceral metastases

Older adults who gain little weight live longer

Intentional weight loss can have positive health benefits in older adults

Innovative system can help manipulate stem cells to repair damaged tissues and organs

Researchers develop absorbable implants to promote bone healing

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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