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Cryo-EM provides new insights into the structure of the centromeric region

The genetic material inside cells is organized into structures called chromosomes. The centromere is essential for the correct division of the chromosomes via interaction with spindle microtubules when cells divide and grow.

6 Feb 2023

Recent therapeutic strategies for renal cell carcinoma and the effects of the tumor microenvironment on systemic therapy

Researchers explored the association between the human microbiome and improved renal cell carcinoma outcomes.

6 Feb 2023

Using genetic risk scores for predicting venous thromboembolism

Researchers assess the predictability of venous thromboembolism among adults using genetic risk scores.

5 Feb 2023

Study reveals a vulnerability of macrophages that contributes to chronic inflammatory diseases

Macrophages are cells of the immune system that, in addition to playing an essential role in the early response to microbial infection, also regulate tissue function and inflammation.

3 Feb 2023

Spontaneous coronary artery dissection: The leading cause of pregnancy-associated heart attacks

Despite increased awareness over the past decades, only about half (56%) of women recognize that heart disease is their No. 1 killer. Heart disease is the leading cause of death for women in the United States, accounting for 1 in every 5 female deaths.

3 Feb 2023

Study elucidates the evolutionary conservation and diversification of auditory neural circuits in fruit flies

When it comes to courtship, it is important to ensure that one is interacting with a member of the same species. Animals use multiple sensory systems to confirm that potential mates are indeed suitable, with acoustic communication playing an important role in their decision making.

3 Feb 2023

Deletion of a tumor suppressor gene promotes luminal breast cancer development and resistance to endocrine therapy

A research team from LKS Faculty of Medicine, the University of Hong Kong (HKUMed) discovered that somatic deletion of a tumor suppressor gene AKTIP promotes luminal breast cancer development and resistance to endocrine therapy.

3 Feb 2023

Researchers discover a new hexameric structure of the RepB protein and how it binds to DNA

In all living organisms, DNA replication is essential to ensure the genetic fidelity of the next generation. However, bacteria can also transfer genetic information horizontally to other bacteria.

3 Feb 2023

World Cancer Day 2023: Perspectives from The Institute of Cancer Therapeutics

To commemorate World Cancer Day, we spoke to a multidisciplinary team of researchers from The Institute of Cancer Therapeutics (ICT) based at the University of Bradford about their work in cancer research.

3 Feb 2023

Pulmonary morphopathology in COVID-19 caused by the B.1.617.2 Delta variant

Researchers examined the histopathological condition of the lungs of patients who died from COVID-19 caused by the SARS-CoV-2 Delta (B.1.617.2) variant.

3 Feb 2023

What is the effect of sex on the clinical characteristics and prognosis of COVID-19 patients?

Researchers evaluated COVID-19 management based on sex differences.

3 Feb 2023

Researchers develop a cell line to address the challenges facing cellular modeling of disease

Bill Skarnes and team established and characterized a stable iPSC line, KOLF2.1J, to act as a high-quality baseline platform for modeling human disease.

3 Feb 2023

Researchers document link between higher risk of maternal mortality and sickle cell disease

Johns Hopkins Medicine researchers have further documented an association between a substantially higher risk of maternal morbidity and mortality among those with the inherited blood disorder sickle cell disease (SCD) compared to those without it.

3 Feb 2023

New nanotechnology-based test can detect and profile prostate cancers even in microscopic amounts

Cedars-Sinai Cancer investigators have developed a new nanotechnology-based test that can detect and profile prostate cancers - even in microscopic amounts.

2 Feb 2023

Unexpected discovery may lead to improved treatments for YAP fusion-driven cancers

An unexpected discovery made by experts at the Brain Tumor Center at Cincinnati Children's while studying a rare-but-deadly type of brain tumor may also lead to improved treatments for several other forms of cancer that share a common influencing factor called a YAP fusion protein.

2 Feb 2023

Genetic News and Research

Cryo-EM provides new insights into the structure of the centromeric region

Recent therapeutic strategies for renal cell carcinoma and the effects of the tumor microenvironment on systemic therapy

Using genetic risk scores for predicting venous thromboembolism

Study reveals a vulnerability of macrophages that contributes to chronic inflammatory diseases

Spontaneous coronary artery dissection: The leading cause of pregnancy-associated heart attacks

Study elucidates the evolutionary conservation and diversification of auditory neural circuits in fruit flies

Deletion of a tumor suppressor gene promotes luminal breast cancer development and resistance to endocrine therapy

Researchers discover a new hexameric structure of the RepB protein and how it binds to DNA

World Cancer Day 2023: Perspectives from The Institute of Cancer Therapeutics

Pulmonary morphopathology in COVID-19 caused by the B.1.617.2 Delta variant

What is the effect of sex on the clinical characteristics and prognosis of COVID-19 patients?

Researchers develop a cell line to address the challenges facing cellular modeling of disease

Researchers document link between higher risk of maternal mortality and sickle cell disease

New nanotechnology-based test can detect and profile prostate cancers even in microscopic amounts

Unexpected discovery may lead to improved treatments for YAP fusion-driven cancers

Understanding the mechanism of bedaquiline resistance in Mycobacterium marinum

UVA researchers discover genes responsible for the development of coronary artery disease

Novel tool uses AI to predict the efficacy of genome-editing repair options

Five major adverse pregnancy outcomes associated with long term risks of ischemic heart disease

People with poor oral health may be more likely to show signs of declining brain health

Genetics & Genomics - Second Edition eBook

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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