Enzyme News and Research

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Enhancers can boost frequency of transcriptional bursting, study shows

A new study by researchers at Princeton University suggests that sporadic bursts of gene activity may be important features of genetic regulation rather than just occasional mishaps.

20 Jul 2016

Researchers discover novel neuroprotection strategies to slow progression of Parkinson's disease

Using a robust model for Parkinson's disease, University of Alabama at Birmingham researchers and colleagues have discovered an interaction in neurons that contributes to Parkinson's disease, and they have shown that drugs now under development may block the process.

20 Jul 2016

Study pinpoints how immune abnormalities in retina may lead to macular degeneration

In a study published this week in the Proceedings of the National Academy of Sciences, a University of Wisconsin-Madison research team pinpoints how immune abnormalities beneath the retina result in macular degeneration, a common condition that often causes blindness.

19 Jul 2016

Scientists capture atomic level snapshots of how key enzyme modifies signaling proteins

Scientists have captured atomic level snapshots showing how one key enzyme modifies a protein involved in turning genes on or off inside cells. Understanding this process-which is particularly important when cells are first taking on specialized identities such as nerve cells, muscle, skin, and so on-helps explain how complex organisms can arise from a finite number of genes.

19 Jul 2016

Modifications to RUNX3 protein may promote cancer progression

Scientists from the Cancer Science Institute of Singapore at the National University of Singapore have discovered that modifications to a protein called RUNX3 may promote cancer progression.

18 Jul 2016

Biochemists design genetic poison pill to thwart coxsackievirus B3

It has a funny name - coxsackievirus - but there's nothing funny about how this tiny germ and its close relatives sicken their hosts.

18 Jul 2016

Scientists discover key 'twist' in Rubik's cube-like plant puzzle

Scientists at the John Innes Centre have discovered a key "twist" in a Rubik's cube-like plant puzzle, which could pave the way to new, or more effective pharmaceuticals.

18 Jul 2016

Findings offer renewed hope for speedy development curative medicines for people with toxoplasmosis

In the July 14 edition of Scientific Reports (Nature), 39 researchers from 14 leading institutions in the United States, United Kingdom and France suggest novel approaches that could hasten the development of better medications for people suffering from toxoplasmosis.

17 Jul 2016

Inability to turn off genes in the brain can affect learning and memory

Every time you play a game of basketball, make a cup of coffee or flick on a light switch, you are turning on genes in your brain. These same genes typically are turned off when the activity ceases - but when that doesn't happen, damaging consequences can occur.

14 Jul 2016

Scientists explore ways to make fat cells function better during obesity

A high-fat diet makes your fat cells larger, inflamed and dysfunctional, putting you at increased risk for diabetes and cardiovascular disease.

14 Jul 2016

Researchers develop new detection systems for genotyping DNA and RNA with naked eye

DNA polymerases are the “Xerox machines” that replicate our DNA. They must work with great precision to keep errors from creeping into our genes.

14 Jul 2016

New diagnostic model may become cheaper and easier alternative to screen for NAFLD

Researchers have developed a diagnostic model that is highly predictive of nonalcoholic fatty liver disease (NAFLD).

13 Jul 2016

Scientists discover new, unexpected features of collagen

Scientists at the National Institutes of Health are reporting new, unexpected details about the fundamental structure of collagen, the most abundant protein in the human body.

13 Jul 2016

Study reveals problems encountered when trying to avoid plastic exposure

The well-known documentary "Plastic Planet" by Werner Boote starkly illustrates the dangers of plastic and synthetics for human beings and also shows how ubiquitous plastic is.

13 Jul 2016

Researchers identify PKD1 protein as potential cause for impaired insulin signaling in diabetics

Medication can help trigger the enzyme that kick starts insulin production in the body, but the drugs don't always work for those who are obese or diabetic, and most need to regulate their glucose and insulin levels. That's why a recent discovery made by Rudy Valentine and a team of researchers holds so much promise.

13 Jul 2016

Scientists identify timing of major metabolic shift in developing neurons

Our brains can survive only for a few minutes without oxygen. Salk Institute researchers have now identified the timing of a dramatic metabolic shift in developing neurons, which makes them become dependent on oxygen as a source of energy.

13 Jul 2016

Researchers identify new mechanism by which bacteria outsmarts immune system

Bacteria are rapidly developing resistance mechanisms to combat even the most effective antibiotics.

13 Jul 2016

Scientists discover new biological defense system against pathogenic microorganisms

For the first time in the world, a group of researchers discovered a human immune receptor, which detects the invasion of pathogenic microorganisms.

13 Jul 2016

Chromatrap reports benefits of ChIP technology in ground breaking research

Chromatrap reports on 3 further customer papers published in different prestigious peer reviewed journals, which cite how its proprietary solid state Chromatin Immunoprecipitation (ChIP) technology has enabled ground breaking research.

From Chromatrap® - Porvair Sciences Ltd 12 Jul 2016

Scientists discover new mechanism by which TNF protects against intracellular pathogens

Tumour necrosis factor (TNF), a messenger substance in the immune system, plays an important role in triggering chronic inflammatory diseases. For this reason, TNF inhibitors are a standard form of treatment for patients with rheumatoid arthritis and certain inflammatory bowel diseases.

11 Jul 2016

Enzyme News and Research

Enhancers can boost frequency of transcriptional bursting, study shows

Researchers discover novel neuroprotection strategies to slow progression of Parkinson's disease

Study pinpoints how immune abnormalities in retina may lead to macular degeneration

Scientists capture atomic level snapshots of how key enzyme modifies signaling proteins

Modifications to RUNX3 protein may promote cancer progression

Biochemists design genetic poison pill to thwart coxsackievirus B3

Scientists discover key 'twist' in Rubik's cube-like plant puzzle

Findings offer renewed hope for speedy development curative medicines for people with toxoplasmosis

Inability to turn off genes in the brain can affect learning and memory

Scientists explore ways to make fat cells function better during obesity

Researchers develop new detection systems for genotyping DNA and RNA with naked eye

New diagnostic model may become cheaper and easier alternative to screen for NAFLD

Scientists discover new, unexpected features of collagen

Study reveals problems encountered when trying to avoid plastic exposure

Researchers identify PKD1 protein as potential cause for impaired insulin signaling in diabetics

Scientists identify timing of major metabolic shift in developing neurons

Researchers identify new mechanism by which bacteria outsmarts immune system

Scientists discover new biological defense system against pathogenic microorganisms

Chromatrap reports benefits of ChIP technology in ground breaking research

Scientists discover new mechanism by which TNF protects against intracellular pathogens

Understanding the DNA Damage Response in Innate Immunity eBook

Latest eBooks

Industry Focus eBook - Analytical Chemistry (3rd edition)

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

Advancing degrader and proximity-based drug development

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo