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Many individuals living with sickle cell disease still lack access to new pain medications

Sickle cell disease (SCD), a rare chronic, progressive, life-threatening, inherited blood disorder, often affects individuals with chronic pain that can be debilitating to their quality of life.

9 Mar 2023

Spike in eating disorders: Millions of people suffer from the condition

Mental health issues clung to COVID-19 like remoras to a shark during the height of the pandemic. And among the most serious were eating disorders.

9 Mar 2023

Individuals with autosomal and X-linked recessive deficiency of IRAK-4 and MyD88 are more susceptible to developing hypoxemic COVID-19 pneumonia

Researchers identified that individuals with a deficiency of myeloid differentiation primary response 88 (MyD88) and interleukin-1 receptor-associated kinase 4 (IRAK-4) due to an autosomal recessive condition were highly susceptible to developing hypoxemic coronavirus disease 2019 (COVID-19) pneumonia when infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

9 Mar 2023

Nasal administration of a fully human anti-CD3 monoclonal antibody modulates T cell inflammatory responses in COVID-19

Researchers assessed the impact of an anti-CD3 monoclonal antibody called Foralumab in COVID-19 treatment.

9 Mar 2023

Gender inequalities in the diagnosis and treatment of peripheral artery disease

Treatments for peripheral artery disease (PAD) were largely developed in men and are less effective in women, according to a review published today in European Heart Journal – Quality of Care and Clinical Outcomes, a journal of the European Society of Cardiology.

8 Mar 2023

Study suggests a new approach for treating metastatic breast cancers

Metastatic breast cancer has no cure and has proven stubbornly resistant to one of the most innovative and promising new cancer treatments: immunotherapy.

8 Mar 2023

Investigating treat-to-target low-density lipoprotein-cholesterol versus high-intensity statins for coronary artery disease

In a recent study published in JAMA, researchers investigated whether treat-to-target (TTT) low-density lipoprotein-cholesterol (LDL-C) therapy was inferior to administering statins of high intensity for clinical outcomes in the long term among coronary artery disease (CAD) patients.

8 Mar 2023

Novel molecular mechanism responsible for common form of acquired hydrocephalus discovered

Mass General researchers have discovered a novel molecular mechanism responsible for the most common forms of acquired hydrocephalus, potentially opening the door to the first-ever nonsurgical treatment for a life-threatening disease that affects about a million Americans.

8 Mar 2023

Detection and targeting of splicing deregulation reveal a potential strategy for pAML therapy

Pediatric acute myeloid leukemia or pAML is a childhood blood cancer, one that has proved confounding to clinicians and researchers, with a high relapse rate and relatively few identified genetic mutations (compared to the adult version) that might explain its cause.

8 Mar 2023

Cedars-Sinai study reveals new insights into the effects of hormonal treatment for transgender men

New insights into the effects of a hormonal treatment for transgender men, discovered by Cedars-Sinai investigators, could have implications for the treatment of breast cancer.

8 Mar 2023

University of Utah and Tikkunlev partner to bring heart failure gene therapy innovation to the clinic

The University of Utah, one of the nation's leading research universities, and TikkunLev Therapeutics, a gene therapy company, have announced a new partnership to accelerate an innovative heart-failure gene therapy.

8 Mar 2023

Study identifies a potential new treatment approach for acute myeloid leukemia

A team of researchers has discovered a potential therapeutic that can synergize with existing drugs to more effectively kill certain leukemia cells.

8 Mar 2023

Does treatment status relate to other diseases in gout patients?

A new study shows how urate-lowering therapy (ULT) is related to such conditions as chronic kidney disease (CKD) and cardiovascular disease (CVD).

8 Mar 2023

Statin-related residual inflammation predicts cardiovascular events and mortality

A recent Lancet study assessed the importance of low-density lipoprotein cholesterol (LDLC) and high-sensitivity C-reactive protein (CRP) as risk predictors of cardiovascular death, cardiovascular events, and all-cause death among patients subjected to statins.

7 Mar 2023

Therapy News and Research

Many individuals living with sickle cell disease still lack access to new pain medications

Spike in eating disorders: Millions of people suffer from the condition

Individuals with autosomal and X-linked recessive deficiency of IRAK-4 and MyD88 are more susceptible to developing hypoxemic COVID-19 pneumonia

Nasal administration of a fully human anti-CD3 monoclonal antibody modulates T cell inflammatory responses in COVID-19

Gender inequalities in the diagnosis and treatment of peripheral artery disease

Study suggests a new approach for treating metastatic breast cancers

Investigating treat-to-target low-density lipoprotein-cholesterol versus high-intensity statins for coronary artery disease

Novel molecular mechanism responsible for common form of acquired hydrocephalus discovered

Detection and targeting of splicing deregulation reveal a potential strategy for pAML therapy

Cedars-Sinai study reveals new insights into the effects of hormonal treatment for transgender men

University of Utah and Tikkunlev partner to bring heart failure gene therapy innovation to the clinic

Study identifies a potential new treatment approach for acute myeloid leukemia

Does treatment status relate to other diseases in gout patients?

Statin-related residual inflammation predicts cardiovascular events and mortality

New blood test examines biomarkers to help determine a person's risk for anxiety

Research shows the benefits of screening AML patients in remission for residual disease before bone marrow transplant

Study finds two substances capable of inhibiting proliferation of glioblastoma cells

Virtual care team strategy found to be safe and effective in improving treatment for heart failure patients

Common scientific method to analyze DNA in early human embryos fails to accurately reflect gene edits

Artificial intelligence for the histological prediction of ulcerative colitis remission

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

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