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DO-HEALTH study aims to provide evidence for strategies that prevent chronic disease in seniors

Europe's largest healthy ageing study - DO-HEALTH - which aims to provide evidence for the safety of three simple preventive interventions: vitamin D, omega-3 fatty acids and a simple home exercise programme, has recruited 532 of its target 2,000 seniors.

10 Sep 2013

Researchers discover why multiple myeloma persistently escapes cure

Clinical researchers at Princess Margaret Cancer Centre have discovered why multiple myeloma, an incurable cancer of the bone marrow, persistently escapes cure by an initially effective treatment that can keep the disease at bay for up to several years.

10 Sep 2013

Combined transplantation provides potential new therapy for repair of spinal cord injury

Following spinal cord injury, astrocyte proliferation and scar formation are the main factors inhibiting the regeneration and growth of spinal cord axons, leading to motor and sensory function loss below the level of spinal cord injury.

10 Sep 2013

UCSF scientists identify new way to manipulate immune system from autoimmune diseases

Scientists from UC San Francisco have identified a new way to manipulate the immune system that may keep it from attacking the body-s own molecules in autoimmune diseases such as type 1 diabetes, rheumatoid arthritis and multiple sclerosis.

10 Sep 2013

BMP linked to increased risk of benign tumors, not cancers

Patients undergoing spinal fusion surgery with bone morphogenetic protein (BMP) appear to be at increased risk of benign tumors—but not cancers, reports a study in the September issue of Neurosurgery, official journal of the Congress of Neurological Surgeons. The journal is published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health.

7 Sep 2013

Non-adherent bone marrow cell-derived mesenchymal stem cells could differentiate into neuronal-like cells

It is widely believed that bone marrow mesenchymal stem cells are highly adherent fibroblastic cells, defined as colony-forming unit-fibroblasts. Nevertheless, a few reports have shown that the non-adherent bone marrow cells can give rise to colony-forming unit-fibroblasts in vitro, and possess a certain differentiation potential.

6 Sep 2013

New research initiative to focus on ultrasound therapy

The Focused Ultrasound Foundation and Philips have entered into an innovative public-private collaboration with The Institute of Cancer Research, London, and The Royal Marsden NHS Foundation Trust.

6 Sep 2013

Greenwich Hospital's new radiation oncology therapy gives renewed hope to HRPC patients

At the end of July, Greenwich became the only hospital in New York City, Westchester and Fairfield counties to offer Xofigo, commonly referred to as Radium 223, a new radiation oncology therapy that is giving renewed hope to patients with stage 4 hormone-refractory prostate cancer.

6 Sep 2013

Apoptosis can reactivate latent herpesviruses in dying cell

Researchers have found that apoptosis, a natural process of programmed cell death, can reactivate latent herpesviruses in the dying cell. The results of their research, which could have broad clinical significance since many cancer chemotherapies cause apoptosis, was published ahead of print in the Journal of Virology.

6 Sep 2013

Osteoporosis drug could provide effective pain relief to patients with osteoarthritis

St George's, University of London research has found that a drug normally given to osteoporosis sufferers could provide effective pain relief to patients with knee and hip osteoarthritis.

6 Sep 2013

$Pivotal Study Supports Use of IMNOVID®▼ Pomalidomide in Patients with Relapsed or Refractory Multiple Myeloma$

Pivotal Study Supports Use of IMNOVID®▼ Pomalidomide in Patients with Relapsed or Refractory Multiple Myeloma

The Lancet Oncology published this week findings from a study, which showed that the new oral therapy IMNOVID®▼ (pomalidomide), used in combination with low-dose dexamethasone demonstrated a significant survival advantage over high-dose dexamethasone alone, in patients with relapsed and refractory multiple myeloma (rrMM).1

5 Sep 2013

Understanding single-sided deafness

Single-sided deafness, or being deaf in one ear, isn't exactly the poster-child for disabilities. Rather, it's an overlooked condition that is often misunderstood by the public. There is no way to see SSD, also called profound unilateral hearing loss, so those who suffer from it are often misperceived as "rude" or "unintelligent" when they don't understand or quickly respond to others. That's just one of the many hidden struggles associated with this condition.

5 Sep 2013

New influenza vaccine delivered via microneedle avoids pain and side effects

Scientists have developed an influenza vaccine delivered via microneedle patch that provided 100 percent protection against a lethal influenza virus in mice more than one year after vaccination. They report their findings in the September 2013 issue of the journal Clinical and Vaccine Immunology.

5 Sep 2013

New systematic review analyzes patterns of vitamin D status worldwide

A new systematic review published in the British Journal of Nutrition, is one of the first to focus on patterns of vitamin D status worldwide and in key population subgroups, using continuous values for 25(OH)D to improve comparisons.

5 Sep 2013

Research findings raise hope for new heart therapies

Many people who survive a heart attack find themselves back in the hospital with a failing heart just years later. And the outcome often is unfavorable, owing to limited treatment options. But scientists at Temple University School of Medicine's Cardiovascular Research Center recently found hope in an unlikely source - stem cells in cortical, or compact, bone.

5 Sep 2013

Ultragenyx, Kyowa Hakko Kirin To Develop Rare Bone Disease-Fighting Mab

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4 Sep 2013

Study identifies new tool to accurately analyze mtDNA deletions associated with diseases, aging

A study published today in Aging Cell identifies a new tool to accurately analyze extremely rare mitochondrial DNA deletions associated with a range of diseases and disorders as well as aging. This approach, which relies on Droplet Digital PCR (ddPCR-) technology, will help researchers explore mtDNA deletions as potential disease biomarkers.

4 Sep 2013

Radiologists train military physicians to remove foreign bodies with ultrasound-guided techniques

William E. Shiels II, DO, chief of the Nationwide Children's Hospital Department of Radiology and president of Children's Radiological Institute, Inc., is leading a team of radiologists for the training of military physicians to remove shrapnel foreign bodies from warfighters with ultrasound-guided techniques that he originally developed, with subsequent improvements made by the full team of Nationwide Children's Hospital interventional radiologists.

4 Sep 2013

UCLA researchers receives $13M Early Translational grants to advance innovative discoveries using stem cells

Four researchers from UCLA's Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research have received Early Translational Research Awards totaling approximately $13 million from the California Institute for Regenerative Medicine, the state's stem cell agency. The UCLA researchers received four of the 12 total awards; no other institution received more than one.

4 Sep 2013

Chronic granulomatous disease (CGD) research: an interview with Dr. Griffin Rodgers, NIDDK director

Chronic granulomatous disease, or CGD, is a diverse group of inherited diseases in which certain cells of the immune system have difficulty forming reactive oxygen compounds, most importantly superoxide radicals. These are used by these white blood cells to kill certain bacteria.

3 Sep 2013

Bone News and Research

DO-HEALTH study aims to provide evidence for strategies that prevent chronic disease in seniors

Researchers discover why multiple myeloma persistently escapes cure

Combined transplantation provides potential new therapy for repair of spinal cord injury

UCSF scientists identify new way to manipulate immune system from autoimmune diseases

BMP linked to increased risk of benign tumors, not cancers

Non-adherent bone marrow cell-derived mesenchymal stem cells could differentiate into neuronal-like cells

New research initiative to focus on ultrasound therapy

Greenwich Hospital's new radiation oncology therapy gives renewed hope to HRPC patients

Apoptosis can reactivate latent herpesviruses in dying cell

Osteoporosis drug could provide effective pain relief to patients with osteoarthritis

Pivotal Study Supports Use of IMNOVID®▼ Pomalidomide in Patients with Relapsed or Refractory Multiple Myeloma

Understanding single-sided deafness

New influenza vaccine delivered via microneedle avoids pain and side effects

New systematic review analyzes patterns of vitamin D status worldwide

Research findings raise hope for new heart therapies

Ultragenyx, Kyowa Hakko Kirin To Develop Rare Bone Disease-Fighting Mab

Study identifies new tool to accurately analyze mtDNA deletions associated with diseases, aging

Radiologists train military physicians to remove foreign bodies with ultrasound-guided techniques

UCLA researchers receives $13M Early Translational grants to advance innovative discoveries using stem cells

Chronic granulomatous disease (CGD) research: an interview with Dr. Griffin Rodgers, NIDDK director

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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