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POZEN reports revenue of $4.6 million for second quarter 2011

POZEN Inc., a pharmaceutical company committed to transforming medicine that transforms lives, today announced results for the second quarter ended June 30, 2011.

28 Jul 2011

SMRT DNA sequencing technology reveals genetic profile of German E. coli bacteria

An international team of scientists has successfully employed single molecule, real-time DNA sequencing technology from Pacific Biosciences of California, Inc. to provide valuable insights into the pathogenicity and evolutionary origins of the highly virulent bacterium responsible for the German E. coli outbreak.

28 Jul 2011

Scientists show how RET gene in breast cancer cells responds to estrogen

Using human breast cancer cells and the protein that causes fireflies to glow, a Johns Hopkins team has shed light on why some breast cancer cells become resistant to the anticancer effects of the drug tamoxifen. The key is a discovery of two genetic "dimmer switches" that apparently control how a breast cancer gene responds to the female hormone estrogen.

28 Jul 2011

Reprogrammed kidney cells could make transplants and dialysis things of the past

Approximately 60 million people across the globe have chronic kidney disease (CKD), and many will need dialysis or a transplant. Breakthrough research published in the Journal of the American Society Nephrology indicates that patients' own kidney cells can be gathered and reprogrammed.

28 Jul 2011

Boehner plan faces delay as debt deal continues to be elusive

The delay was caused both by a Congressional Budget Office analysis that found the proposal by House Speaker John Boehner didn't score the promised savings and by conservatives' skepticism about the plan.

28 Jul 2011

Researchers identify gene linked to Lesch-Nyhan disease

In humans, inherited mutations in a gene called HPRT1 lead to very specific self-destructive behavior. Boys with Lesch-Nyhan disease experience uncontrollable urges to bite their fingers, slam their arms into doorways and otherwise harm themselves.

28 Jul 2011

Social media may improve public health system's ability to prepare, recover from disasters

Social media tools like Facebook, Twitter and Foursquare may be an important key to improving the public health system's ability to prepare for, respond to, and recover from disasters, according to a New England Journal of Medicine "Perspective" article from the Perelman School of Medicine at the University of Pennsylvania to be published this week.

28 Jul 2011

UM researchers unravel genomic code of German E. coli bacteria

A team led by University of Maryland School of Medicine Institute for Genome Sciences researchers has unraveled the genomic code of the E. coli bacteria that caused the ongoing deadly outbreak in Germany that began in May 2011.

28 Jul 2011

Noninvasive brain computer interface could turn thoughts into motion

"Brain cap" technology being developed at the University of Maryland allows users to turn their thoughts into motion. Associate Professor of Kinesiology José 'Pepe' L. Contreras-Vidal and his team have created a non-invasive, sensor-lined cap with neural interface software that soon could be used to control computers, robotic prosthetic limbs, motorized wheelchairs and even digital avatars.

28 Jul 2011

Structural changes associated with frequent exacerbations identified in lungs of COPD patients

Using computed tomography (CT), researchers have identified two types of structural changes in the lungs of patients with chronic obstructive pulmonary disease (COPD) that are associated with frequent exacerbations, or episodes when symptoms suddenly worsen. Their findings are published online in the journal Radiology.

28 Jul 2011

University of Pittsburgh to honor Synthetic Genomics CEO with Dickson Prize

The scientist-entrepreneur who led efforts to map the first draft of the human genome as well as the complete diploid genome and to construct the first synthetic bacterium has been named this year's recipient of the University of Pittsburgh's Dickson Prize in Medicine.

28 Jul 2011

Dilemma of single vs. double embryo transfers

Elsevier announced the publication of several commentaries in the scientific journal Reproductive BioMedicine Online on the subject of how many embryos it is safe and proper to place in a uterus, and how best to regulate this decision. It is a dilemma faced by all patients anxiously caught between no pregnancies at all or facing the prospect of twins or triplets. In this difficult place it is often all too easy to think that the latter option must be the best. But is it?

28 Jul 2011

Researchers draw on ontology to define pain

All over the world, patients with chronic pain struggle to express how they feel to the doctors and health-care providers who are trying to understand and treat them. Now, a University at Buffalo psychiatrist is attempting to help patients suffering from chronic pain and their doctors by drawing on ontology, the branch of philosophy concerned with the nature of being or existence.

28 Jul 2011

New study shows high prevalence of gout in the U.S.

A new study shows the prevalence of gout in the U.S. has risen over the last twenty years and now affects 8.3 million (4%) Americans.

28 Jul 2011

Insect virus holds key to safer stem cell therapy: Singapore scientists

The future of regenerative medicine lies in harnessing the potential of the human body to renew and repair itself. Now, scientists at the Institute of Bioengineering and Nanotechnology (IBN), the world's first bioengineering and nanotechnology research institute, have developed a new genetic engineering technique that promises safer stem cell therapy for cancer patients. Using an insect virus, the team of researchers successfully inserted a therapeutic gene into a safe site in the DNA of human embryonic stem cells without compromising the functionality of the engineered cells.

28 Jul 2011

OR models verify cost effectiveness of hepatitis B interventions

With hepatitis B infecting as many as 10% of people of Asian descent, operations researchers collaborated with a liver transplant surgeon to develop mathematical models that verified the cost effectiveness of hepatitis B interventions.

27 Jul 2011

Virtual reality study to address alcohol abuse issues in veterans

The spoils of war for returning veterans may include addictions, injury and the constant images of horrific events they witnessed. Now a University of Houston joint study funded by the Veterans Health Administration Rehabilitation Research and Development service looks to address these issues through the use of virtual reality.

27 Jul 2011

Scientists reveal complete three-dimensional atomic structure of an activated GPCR

G protein-coupled receptors (GPCRs) are popular drug targets, accounting for about one-third of approved drugs and many hundreds of drugs currently in development. They act as molecular switches that transduce extracellular signals by activating heterotrimeric G proteins located at the inside of the cell.

27 Jul 2011

Mayo Clinic releases recommendations from the ice hockey concussion summit

Mayo Clinic has released recommendations from the Ice Hockey Summit on Concussion: A Call to Action. The summit attracted top scientists, trainers, coaches, officials and equipment manufacturers from across the United States, Canada and Europe to discuss concussion-related issues, including the science of concussions, impact on children, and prevention.

27 Jul 2011

All football players do not get chronic traumatic encephalopathy

Preliminary results from the first four brains donated to the Canadian Sports Concussion Project at the Krembil Neuroscience Centre, TorontoWesternHospital, reveal that two of the four former Canadian Football League (CFL) players suffered from a brain disease known as Chronic Traumatic Encephalopathy (CTE), while two did not show signs of CTE.

27 Jul 2011