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Older adults still at highest risk of COVID-19 despite high vaccination rates

About 80% of residents in the Lower Mainland, British Columbia, had been infected with SARS-CoV-2 by July 2023 and were at low risk for severe outcomes, but almost half of the oldest adults remained uninfected and were at highest risk of hospitalization and death due to COVID-19, according to a new study published in CMAJ (Canadian Medical Association Journal) https://www.cmaj.ca/lookup/doi/10.1503/cmaj.230721.

30 Oct 2023

Diabetic patients with COVID-19: low antibody levels linked to worse outcomes

The role of anti-SARS-CoV-2 antibody levels on COVID-19 outcomes in patients with T2D.

30 Oct 2023

How does the Mediterranean diet impact insulin resistance and sensitivity in obese individuals?

Researchers evaluate the associations between adherence to the Mediterranean diet, insulin secretion, resistance, and sensitivity in obese individuals.

30 Oct 2023

Machine learning sheds light on mental health challenges faced by HCWs during COVID-19 pandemic

Machine learning reveals unique mental health struggles among healthcare workers during the COVID-19 pandemic, highlighting the urgent need for specialized support. The study analyzed therapy transcripts to show how healthcare professionals faced distinct challenges, including heightened anxiety and depression.

29 Oct 2023

MHRA grants conditional marketing authorization for AbbVie's Tepkinly to treat aggressive blood cancer

AbbVie today announced that the UK Medicines and Healthcare products Regulatory Agency has granted conditional Marketing Authorisation for Tepkinly® (epcoritamab) as a monotherapy for the treatment of adults with relapsed or refractory (R/R) diffuse large B-cell lymphoma (DLBCL), after two or more systemic therapies.

28 Oct 2023

Loss of structural protein ACTL7B blocks spermatogenesis in male mice

Mature spermatozoa are characterized by an head, midpiece and a long tail for locomotion. Now, researchers from the University Hospital Bonn (UKB) and the Transdisciplinary Research Unit "Life & Health" at the University of Bonn have found that a loss of the structural protein ACTL7B blocks spermatogenesis in male mice.

27 Oct 2023

RF-CBT reduces rumination and shifts brain connectivity in adolescents with depression

A new study from The Ohio State University Wexner Medical Center and College of Medicine, University of Utah and University of Exeter (UK) substantiates previous groundbreaking research that rumination (overthinking) can be reduced through an intervention called Rumination-focused Cognitive Behavioral Therapy (RF-CBT).

27 Oct 2023

UC San Diego Health and Tri-City partnership aims to expand, transform access to health care

After open public discussion and a unanimous board vote, Tri-City Healthcare District ("Tri-City" or "District") announced yesterday that UC San Diego Health has been selected as the District's future health care partner.

27 Oct 2023

Medical-legal partnerships can help improve maternal and infant health outcomes

Medical-legal partnerships (MLPs), which include a lawyer as part of a patient's care team, can help health systems address health-harming legal needs and better support pregnant and postpartum patients, according to a new research commentary published today in Obstetrics & Gynecology.

27 Oct 2023

FDA approves a new steroidal-type anti-inflammatory drug for Duchenne muscular dystrophy

Boys with Duchenne muscular dystrophy (DMD) have a clinically proven, new treatment option with the Food and Drug Administration's approval Thursday of vamorolone, a steroidal-type, anti-inflammatory drug developed based on research performed at Children's National Hospital.

27 Oct 2023

Long COVID prevalence high in Scandinavians with severe COVID-19

A collaborative study involving researchers from Karolinska Institutet has charted the prevalence of severe physical symptom burden amongst Scandinavians for up to two years after a SARS-CoV-2 infection.

27 Oct 2023

Smaller employers weigh a big-company fix for scarce primary care: Their own clinics

With his company's health costs soaring and his workers struggling with high blood pressure and other medical conditions, Winston Griffin, CEO of Laurel Grocery Co., knew his company had to do something.

27 Oct 2023

A new era of vaccines leaves old questions about prices unanswered

The world is entering a new era of vaccines. Following the success of covid-19 mRNA shots, scientists have a far greater capacity to tailor shots to a virus's structure, putting a host of new vaccines on the horizon.

27 Oct 2023

New drug candidate found to be highly effective in treating rare sight-threatening eye infection

A drug candidate, based on pioneering UCL and Moorfields Eye Hospital research and currently under development by SIFI S.p.A., has been found to be highly effective in treating a rare sight-threatening eye infection in a new international clinical trial.

26 Oct 2023

City of Hope, TGen receive $4.5 million to validate liquid biopsy for early detection of pancreatic cancer

City of Hope, one of the largest cancer research and treatment organizations in the United States, and TGen are leading an international group that has been awarded $4.5 million to validate a liquid biopsy for the early detection of pancreatic cancer.

26 Oct 2023

Exploring the link between red meat intake and inflammation

Inflammation is a risk factor for many chronic diseases, including cardiovascular disease (CVD), and the impact of diet on inflammation is an area of growing scientific interest.

26 Oct 2023

Newly identified amino acid may play key role in predicting outcomes and treatment of long COVID

University of Alberta researchers have identified an amino acid that may play a key role in predicting poor clinical outcomes and the treatment of long COVID.

26 Oct 2023

Genomic screening encourages people with hemochromatosis to seek treatment and relevant management

Genomic screening to identify hemochromatosis - a disorder that causes iron levels in the body to rise to dangerous levels - encourages people with the condition to seek treatment and ongoing management, a Geisinger study found.

26 Oct 2023

Immunologists aim to explore new avenues for immunotherapy of liver metastases

Four distinguished immunologists have been awarded one of the most generously funded research grants from the EU: the ERC Synergy Grant.

26 Oct 2023

Treatment in ambulance-based mobile stroke unit increases the likelihood of averting strokes

Receiving a clot-busting drug in an ambulance-based mobile stroke unit (MSU) increases the likelihood of averting strokes and complete recovery compared with standard hospital emergency care, according to researchers at Weill Cornell Medicine, NewYork-Presbyterian, UTHealth Houston, Memorial Hermann-Texas Medical Center and five other medical centers across the United States.

26 Oct 2023

Hospital News and Research

Older adults still at highest risk of COVID-19 despite high vaccination rates

Diabetic patients with COVID-19: low antibody levels linked to worse outcomes

How does the Mediterranean diet impact insulin resistance and sensitivity in obese individuals?

Machine learning sheds light on mental health challenges faced by HCWs during COVID-19 pandemic

MHRA grants conditional marketing authorization for AbbVie's Tepkinly to treat aggressive blood cancer

Loss of structural protein ACTL7B blocks spermatogenesis in male mice

RF-CBT reduces rumination and shifts brain connectivity in adolescents with depression

UC San Diego Health and Tri-City partnership aims to expand, transform access to health care

Medical-legal partnerships can help improve maternal and infant health outcomes

FDA approves a new steroidal-type anti-inflammatory drug for Duchenne muscular dystrophy

Long COVID prevalence high in Scandinavians with severe COVID-19

Smaller employers weigh a big-company fix for scarce primary care: Their own clinics

A new era of vaccines leaves old questions about prices unanswered

New drug candidate found to be highly effective in treating rare sight-threatening eye infection

City of Hope, TGen receive $4.5 million to validate liquid biopsy for early detection of pancreatic cancer

Exploring the link between red meat intake and inflammation

Newly identified amino acid may play key role in predicting outcomes and treatment of long COVID

Genomic screening encourages people with hemochromatosis to seek treatment and relevant management

Immunologists aim to explore new avenues for immunotherapy of liver metastases

Treatment in ambulance-based mobile stroke unit increases the likelihood of averting strokes

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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