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GEN article reports on new drug research and development costs

A policy specialist and a healthcare economist both say that the oft-quoted cost of $1.32 billion to bring a new drug to market does not hold up to close scrutiny, reports Genetic Engineering & Biotechnology News.

7 Jul 2011

Study finds link between genetic variation and cetuximab rectal cancer therapy

team of researchers led by Keck School of Medicine of the University of Southern California (USC) oncologist Heinz-Josef Lenz, M.D., has identified a genetic marker that may predict which patients with rectal cancer can be cured by certain chemotherapies when combined with surgery.

7 Jul 2011

Gene therapy may help prevent progression of type 1 diabetes

Increasing a specific protein in areas of the pancreas that produce insulin blocks the immune attack that causes type 1 diabetes, researchers reported in the August issue of the Journal of Clinical Investigation, published early online.

7 Jul 2011

Improved global safety monitoring of HIV drugs is needed

With at least five million people worldwide taking antiretroviral therapy for HIV infection, the International Forum for Collaborative HIV Research, in a PLoS Medicine Policy Forum published on Tuesday, "recommends that improved and sustained global drug safety monitoring, including monitoring for substandard products, drug diversion, inappropriate use, and toxicity, is critical," a press release from PLoS states.

7 Jul 2011

New data compares gender effect on survival after abdominal aortic aneurysm repair

New data in the July 2011 issue of the Journal of Vascular Surgery, the official publication of the Society for Vascular Surgery, compares the effects of gender on long-term survival in different types of abdominal aortic aneurysm (AAA) repair.

7 Jul 2011

U.S. needs supply of medical professionals to meet goals of health-care reform

One consequence of the expanded access to health care facilitated by health care reform will be a shortfall in the necessary numbers of physicians and other advanced medical professionals.

7 Jul 2011

Eighteen scientists receive Damon Runyon Cancer Research Foundation awards

The Damon Runyon Cancer Research Foundation, a non-profit organization focused on supporting innovative early career researchers, named 18 new Damon Runyon Fellows at its spring Fellowship Award Committee review.

7 Jul 2011

Review identifies RDTs as effective tool to fight malaria

"A new Cochrane Systematic Review examines the accuracy of Rapid Diagnostic Tests (RDTs), which are designed to detect malaria based on the presence of parasite antigens, using a quick and easy to use format," according to a press release issued by Wiley.

7 Jul 2011

Toxic waste exposure impacts residents' health in Campania Region

Scientific evidence is mounting in support of a significant increase in cancer mortality and malformations occurring in specific areas of the Campania Region of Southern Italy, where improper waste management and illegal waste trafficking have been repeatedly documented, according to "Wasting lives: the effects of toxic waste exposure on health.

7 Jul 2011

Study finds top grand challenges in global mental health

A Toronto-based researcher is at the helm of a massive, worldwide study that identifies the top global challenges in mental health. The paper resulting from the study appears in Nature today.

7 Jul 2011

First transcatheter aortic valve implantation performed at Loyola University Hospital

Toni Meyer's heart-valve disease was so severe that she suffered shortness of breath even while sitting in a chair. But after Loyola University Hospital physicians replaced her diseased aortic valve in a catheter procedure as part of a clinical trial, Meyer said she is feeling "100 percent better."

From Medtronic 7 Jul 2011

Study links physician leaders with hospital performance

Top-performing hospitals are typically ones headed by a medical doctor rather than a manager. That is the finding from a new study of what makes a good hospital.

7 Jul 2011

Simpler antibiotic combination could help prevent TB in patients with and without HIV

Johns Hopkins and South African scientists have further compelling evidence that new, simpler and shorter treatments with antibiotic drugs could dramatically help prevent tens of millions of people worldwide already infected with the bacterium responsible for tuberculosis, and especially those co-infected with HIV, from developing full-blown TB.

7 Jul 2011

Men more likely to fake soccer injuries than women

With the Women's World Cup in full swing in Germany, soccer fans can now rest assured that women are less likely than men to fake on-field injuries, according to a new study by researchers at Wake Forest Baptist Medical Center published in the July issue of the journal Research in Sports Medicine.

7 Jul 2011

Scientists identify molecular mechanism behind alcohol-induced blackouts

A person who drinks too much alcohol may be able to perform complicated tasks, such as dancing, carrying on a conversation or even driving a car, but later have no memory of those escapades. These periods of amnesia, commonly known as "blackouts," can last from a few minutes to several hours.

7 Jul 2011

Unhealthy lifestyle linked to increased risk of sexual dysfunction in men

A new study published in The Journal of Sexual Medicine reveals that several unhealthy lifestyle factors, such as weight problems, physical inactivity, high alcohol consumption, tobacco smoking, and hard drugs are associated with sexual dysfunctions in men. Additionally, an unhealthy lifestyle is more common in persons who are sexually inactive.

7 Jul 2011

Freeze-dried gene therapy system safe and effective for treating brain cancer

Researchers at the Johns Hopkins University School of Medicine have developed a technique that delivers gene therapy into human brain cancer cells using nanoparticles that can be freeze-dried and stored for up to three months prior to use. The shelf-stable particles may obviate the need for virus-mediated gene therapy, which has been associated with safety concerns.

7 Jul 2011

Viewpoints: Preserving Medicaid; drug risks, headlines; health law flaw

The poor and disabled people who rely on Medicaid to pay their medical bills could be in grave jeopardy in this sour I've-got-mine political climate. Older Americans, a potent voting bloc, have made clear that they won't stand for serious changes in Medicare. Medicaid, however, provides health insurance for the most vulnerable, who have far less political clout.

7 Jul 2011

Ovarian cells are stiffer and more viscous when benign

Using ovarian surface epithelial cells from mice, researchers from Virginia Tech have released findings from a study that they believe will help in cancer risk assessment, cancer diagnosis, and treatment efficiency in a technical journal: Nanomedicine.

6 Jul 2011

Fiscal problems could be mitigated by ART conceived children

In 2009, 1,547 ART children were born in public clinics in Denmark, projecting a net tax revenue of -224 million and -247 million in 25 and 50 years respectively. The authors of the study calculated that reductions of 30-50% in ART cycles following the new policy would lead to cost savings of -67 - -111 million for the Danish government in 2034.

6 Jul 2011