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Homeless Intermediate Care Pilot Project helps reduce hospital, ED admissions

A nurse outreach programme to treat people using a homeless shelter in London led to a fall of 77 per cent in hospital admissions from the shelter and a cut of 52 per cent in emergency department attendances.

12 Oct 2012

New mass spectrometry helps identify bacteria in clinical specimens within minutes

New mass spectrometry technology is helping Le Bonheur Children's physicians analyze microbiology samples quickly - identifying specific bacteria present in a sample within minutes.

11 Oct 2012

Study finds how MAIT cells recognize products of vitamin B synthesis from bacteria and yeast

An Australian research team has discovered how specialised immune cells recognise products of vitamin B synthesis that are unique to bacteria and yeast, triggering the body to fight infection.

11 Oct 2012

Xenex Healthcare Services receives GSA contract to purchase room disinfection systems

Xenex Healthcare Services, the world leader in UV room disinfection systems, today announced it has been awarded a U.S. General Services Administration (GSA) contract, making it even easier for federal agencies (including Veterans Affairs hospital systems) to purchase Xenex's room disinfection systems.

11 Oct 2012

Bacterial pathogen ‘acutely’ involved in otitis media

Alloiococcus otitidis can be a dominant bacterial pathogen among indigenous Australian children with acute otitis media with perforation, although its main role appears to be that of a secondary pathogen, preliminary study findings suggest.

10 Oct 2012

Chronic kidney disease changes the composition of intestinal bacterial microbes

Chronic kidney disease changes the composition of intestinal bacterial microbes that normally play a crucial role in staving off disease-causing pathogens and maintaining micronutrient balance, according to UC Irvine researchers.

10 Oct 2012

T2R38 taste receptor regulates immune defense of the human upper airway

The immune system protects the upper respiratory tract from bacterial infections, but the cues that alert the immune system to the presence of bacteria are not known. In this issue of the Journal of Clinical Investigation, researchers led by Noam Cohen at the University of Pennsylvania demonstrated that the bitter taste receptor T2R38 regulates the immune defense of the human upper airway.

9 Oct 2012

Standard red blood cell transfusion as good as fresh RBCs for premature infants

Among premature, very low-birth-weight infants requiring a transfusion, use of fresh red blood cells (RBCs) compared with standard RBC transfusion practice did not improve clinical outcomes that included rates of complications or death, according to a study in the October 10 issue of JAMA.

8 Oct 2012

NCI awards Cellerant SBIR contract to develop Megakaryocyte Progenitor Cell therapy for thrombocytopenia

Cellerant Therapeutics Inc., a biotechnology company developing novel hematopoietic stem cell-based cellular and antibody therapies for blood disorders and cancer, announced today that it has been awarded a Small Business Innovation Research (SBIR) Phase 1 contract and a Phase 2 option from the National Cancer Institute (NCI) valued up to $1,683,503.

8 Oct 2012

Positive results from Cempra's IV solithromycin Phase 1 study

Cempra, Inc., a clinical-stage pharmaceutical company focused on developing antibiotics to meet critical medical needs in the treatment of bacterial infectious diseases, today announced results of its Phase 1 study of intravenous (IV) solithromycin in healthy subjects. The study demonstrated that IV solithromycin was well tolerated, showed a favorable pharmacokinetic profile (PK) and achieved relevant plasma concentrations.

8 Oct 2012

Researchers discover smallest and fastest-known RNA switches

A University of Michigan biophysical chemist and his colleagues have discovered the smallest and fastest-known molecular switches made of RNA, the chemical cousin of DNA. The researchers say these rare, fleeting structures are prime targets for the development of new antiviral and antibiotic drugs.

8 Oct 2012

Progress toward preventing initial and recurrent episodes of C. diff infection

Surgeons are making progress toward preventing initial and recurrent episodes of clostridium difficile colitis (C. difficile or C. diff), a vicious bacterial infection that is estimated to affect about 336,000 people each year, typically patients on antibiotics.

6 Oct 2012

Diabecline wins Drug Store News Best New Product award

Diabecline first aid antibiotic, offered by pharmaCline, has been named the winner of the Drug Store News Best New Product award.

5 Oct 2012

New technique has potential to kill off hospital superbugs

Scientists at Queen's University Belfast have developed a new technique which has the potential to kill off hospital superbugs like Pseudomonas aeruginosa, C. difficile and MRSA.

5 Oct 2012

Respiratory infections provide urban asthma clue

Urban infants have a different pattern of viral respiratory illness from suburban infants, which could help explain why they are more likely to develop asthma, say US researchers.

2 Oct 2012

Regional, seasonal variation in US antibiotic use highlights persisting issue

US study results reveal “substantial” quarterly and regional variation in outpatient antibiotic use among older adults, indicating the possible need for targeted programs to reduce unnecessary prescriptions.

1 Oct 2012

Research roundup: Saving money with hospital observation units, total knee replacement rates skyrocketing, Medicare patients and antibiotic overuse

The authors write: Using observation units in hospitals to provide care to certain patients can be more efficient than admitting them to the hospital and can result in shorter lengths-of-stay and lower costs. However, such units are present in only about one-third of US hospitals.

29 Sep 2012

Key bacterial protein structures reveal one of the biochemical secrets behind multi-drug tolerance

The structures of key bacterial proteins have revealed one of the biochemical secrets that enables bacteria to outwit antibiotics.

27 Sep 2012

Type 2 diabetes may be derived from composition of specific intestinal flora

Whether you have an increased risk of developing type 2 diabetes, in the future may be derived from the composition of your intestinal flora. That according to new metagenomics research of an international consortium of scientists, including Jeroen Raes, connected to VIB and Vrije Universiteit Brussel. Metagenomics is the study of the genetic material of complete ecosystems, in this case the human intestine. This study appears in the leading journal Nature.

27 Sep 2012

IV connectors can play a crucial role in protecting patients from infections and other complications

Medical devices known as IV connectors, through which intravenous medication and nutrition are provided to a patient, can play a crucial role in protecting patients from life-threatening infections and other complications. But some types of connectors are much more prone to dangerous complications, according to a recent poster presentation at an international meeting of oncology nurses, the 17th International Conference on Cancer Nursing, held Sept. 9-13 in Prague, Czech Republic.

26 Sep 2012

Bacterial News and Research

Homeless Intermediate Care Pilot Project helps reduce hospital, ED admissions

New mass spectrometry helps identify bacteria in clinical specimens within minutes

Study finds how MAIT cells recognize products of vitamin B synthesis from bacteria and yeast

Xenex Healthcare Services receives GSA contract to purchase room disinfection systems

Bacterial pathogen ‘acutely’ involved in otitis media

Chronic kidney disease changes the composition of intestinal bacterial microbes

T2R38 taste receptor regulates immune defense of the human upper airway

Standard red blood cell transfusion as good as fresh RBCs for premature infants

NCI awards Cellerant SBIR contract to develop Megakaryocyte Progenitor Cell therapy for thrombocytopenia

Positive results from Cempra's IV solithromycin Phase 1 study

Researchers discover smallest and fastest-known RNA switches

Progress toward preventing initial and recurrent episodes of C. diff infection

Diabecline wins Drug Store News Best New Product award

New technique has potential to kill off hospital superbugs

Respiratory infections provide urban asthma clue

Regional, seasonal variation in US antibiotic use highlights persisting issue

Research roundup: Saving money with hospital observation units, total knee replacement rates skyrocketing, Medicare patients and antibiotic overuse

Key bacterial protein structures reveal one of the biochemical secrets behind multi-drug tolerance

Type 2 diabetes may be derived from composition of specific intestinal flora

IV connectors can play a crucial role in protecting patients from infections and other complications

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