Compound News and Research

RSS

Losing weight through calorie cutting won't lead to increased disability in older women

Unintentional weight loss in older adults often leads to frailty, a decline in physical function and even death.

8 May 2007

Diabetes drug rosiglitazone boosts power of platinum chemotherapy

A widely used diabetes drug dramatically boosted the potency of platinum-based cancer drugs when administered together to a variety of cancer cell lines and to mice with tumors, scientists from Dana-Farber Cancer Institute report.

8 May 2007

Scientists delete enzyme in mice so they can eat any type of fat and not get heart disease

A new study in mice raises a tantalizing possibility, that humans may one day be able to eat any kind of fat they want without raising their risk of heart disease.

8 May 2007

New vitamin extends lifespan in yeast cells

Imagine taking a vitamin for longevity! Not yet, but a Dartmouth discovery that a cousin of niacin prolongs lifespan in yeast brings the tantalizing possibility a step closer.

4 May 2007

Renewal of Echinacea and St John's Wort research

A five-year-old research center dedicated to understanding and improving Echinacea and Hypericum perforatum (St. John's wort) has received $4.4 million in continuation funding from the National Institutes of Health. The renewal is for three years.

4 May 2007

Phenoxodiol, an investigational drug shows promise for ovarian cancer

A new study further supports the unique mechanism of action of phenoxodiol, an investigational drug being studied for the treatment of ovarian cancer.

2 May 2007

Green tea shows potential for HIV-associated dementia prevention

A compound derived from green tea greatly diminished the neurotoxicity of proteins secreted by the human immunodeficiency virus, suggesting a new approach to the prevention and treatment of HIV-associated dementia, also known as AIDS dementia complex.

2 May 2007

Spherix starts phase 3 clinical trial of treatment for type 2 diabetes

Spherix Incorporated has announced that it has begun its Phase 3 clinical trial of Naturlose as a treatment for Type 2 diabetes.

2 May 2007

Wrapping version of Gleevec fights drug-resistant cancer

A new study highlighted on the cover of this week's issue of Cancer Research finds that the anti-cancer drug Gleevec? is far more effective against a drug-resistant strain of cancer when the drug wraps the target with a molecular bandage that seals out water from a critical area.

2 May 2007

New compounds show potential for cognitive disorders

UC Irvine researchers have identified a new class of compounds that could be used for drugs to treat cognitive disorders that accompany schizophrenia, Alzheimer's disease and ADHD, according to an article published today in the online version of the Proceedings of the National Academy of Sciences.

2 May 2007

New class of nontoxic cancer treatments

A new class of compounds developed by two University of Kentucky researchers shows promise as a nontoxic treatment of some cancers previously treated with toxic chemotherapy, the researchers report today.

2 May 2007

Traditional African medicines may hold potential for treating high blood pressure

Medicinal plants are an integral part of African culture, one of the oldest and most diverse in the world.

2 May 2007

Avicena files composition of matter patent application for treatment of Huntington's disease

Avicena Group has announced day that it has filed a composition of matter patent application with the United States Patent and Trademark Office (USPTO) to cover potential treatments for Huntington's disease, a fatal neurodegenerative disease.

1 May 2007

Scientists find last unknown enzyme in the synthesis of vitamin C in plants

Vitamin C is possibly the most important small molecule whose biosynthetic pathway remained a mystery.

30 Apr 2007

Green tea may help prevent bone destruction in arthritis

In rheumatoid arthritis, a person's own immune system attacks the joints by activating the synovial tissue that lines the body's movable joints, causing inflammation, swelling, pain and eventually erosion of the bone and cartilage and deformation of the joint.

30 Apr 2007

Chinese herb Lei Gong Teng stops formation of cysts in polycystic kidney disease in lab

Using a compound from a centuries-old Chinese traditional medicine, Yale University researcher Dr. Craig Crews has been able to prevent the formation of kidney-destroying cysts in a mouse model of polycystic kidney disease.

30 Apr 2007

Anti-dandruff compound may be a potential treatment for seizures

Researchers at Johns Hopkins have discovered that the same ingredient used in dandruff shampoos to fight the burning, itching and flaking on your head also can calm overexcited nerve cells inside your head, making it a potential treatment for seizures.

30 Apr 2007