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Genetic variation associated with increased risk of sudden cardiac arrest

A study by a global consortium of physician-scientists has identified a genetic variation that may predispose people to double the risk of having a sudden cardiac arrest, a disorder that gives little warning and is fatal in about 95 percent of cases.

1 Jul 2011

Tranexamic acid effective for patients with head injury

New research has suggested that tranexamic acid has the potential to prevent people dying from head injuries.

1 Jul 2011

Some generic anti-epilepsy drugs may not be effective

30 Jun 2011

Study confirms benefits of low-dose spiral CT scans for lung cancer detection

The New England Journal of Medicine's (NEJM) headline today read, "Reduced Lung Cancer Mortality with Low-Dose Computed Tomographic CT Screening," ending a long controversy over the use of an existing but underutilized early detection tool for those at risk for Lung Cancer. Preliminary results of the National Lung Screening Trial (NLST) were first released on November 4, 2010 and confirmed today.

30 Jun 2011

Lotus Tissue Repair to develop DEB protein replacement therapy with $26 million Series A financing

Lotus Tissue Repair, Inc. today announced the closing of a $26 million Series A financing led by Third Rock Ventures. Proceeds of the financing will be used to advance the company's proprietary recombinant collagen type VII (rC7) technology as the first and only protein replacement therapy in development for the treatment of dystrophic epidermolysis bullosa (DEB), an orphan disease that causes devastating skin blisters, morbidity and early mortality.

30 Jun 2011

Harvard University, UCB enter innovative research collaboration

UCB and Harvard University officially launched their innovative Research Alliance during a signing ceremony that took place in Boston last night in the presence of his Royal Highness Prince Philippe of Belgium.

30 Jun 2011

Child psychiatrists update mental illness handbook to guide clinicians and students

The 4th edition of the Concise Guide to Child & Adolescent Psychiatry, written by Children's Memorial Hospital's psychiatrists, Mina Dulcan, MD, and Mary Beth Lake, MD., was published in July by American Psychiatric Publishing. Dulcan is department head of Child and Adolescent Psychiatry at Children's Memorial and professor at Northwestern University Feinberg School of Medicine.

30 Jun 2011

Workers who take mental health leave more likely to have second episode sooner

The recurrence of an employee's medical leave of absence from work tends to happen much sooner with a mental health leave than a physical one, a Centre for Addiction and Mental Health (CAMH) study shows.

30 Jun 2011

IOM report can set the stage for improvements in pain care, says APS

The American Pain Society (APS) said that "Relieving Pain in America: A Blueprint for Transforming Prevention, Treatment, and Research, the report submitted to Congress today by the Institute of Medicine, is a major step forward in addressing the nation's leading public health problem - untreated and undertreated chronic pain.

30 Jun 2011

Research raises questions about some generic epilepsy drugs

Generic anti-epilepsy drugs, pharmaceutical products similar to brand-name versions, save consumers billions of dollars each year, but some are different enough from branded formulations that they may not be effective, particularly if patients switch between two generic drugs, a new study by Johns Hopkins researchers suggests. A report on the study, published online and in an upcoming issue of Annals of Neurology, raises questions about whether some generic products are safe and effective when a narrow dose range separates patients from help and harm.

30 Jun 2011

Brain stem cells shown to generate multiple new brain stem cells

A Johns Hopkins team has discovered in young adult mice that a lone brain stem cell is capable not only of replacing itself and giving rise to specialized neurons and glia – important types of brain cells – but also of taking a wholly unexpected path: generating two new brain stem cells.

30 Jun 2011

Surgical complications much more likely in obese patients

Obese patients are nearly 12 times more likely to suffer a complication following elective plastic surgery than their normal-weight counterparts, according to new research by Johns Hopkins scientists.

30 Jun 2011

Text messages help smokers quit: Study

A behavioral study has found that motivational text messages sent to smokers' mobile phones can double their chances of giving up tobacco. The “txt2stop” trial at London School of Hygiene and Tropical Medicine (LSHTM) and funded by the Medical Research Council tested the effects of inspirational text messages designed to encourage quitting on almost 3,000 smokers. Participants were twice as likely to banish their habit as another group sent texts unrelated to smoking.

30 Jun 2011

Energy density, portion size and eating occasions contribute to obesity epidemic in the U.S.

Over the past 30 years U.S. adults have been eating larger portions and eating more often, according to a new study by University of North Carolina at Chapel Hill researchers.

30 Jun 2011

100 million Americans suffer pain - many in silence

According to a report released by the Institute of Medicine Wednesday, nearly a third of Americans experience long-lasting pain and too often feel stigma rather than relief from a health care system poorly prepared to treat them. Chronic pain is costing the nation at least $558 billion a year in medical bills, sick days and lost productivity, the report found. That's more than the cost of heart disease, the top killer.

30 Jun 2011

Lung cancer screenings reduce risk of dying by 20%: Study

A lnew study shows some smokers' lives could be saved by screening with lung scans and the chances improve further if there is a false alarm.

30 Jun 2011

Swaziland's supply of antiretroviral drugs running low

"Cash-strapped Swaziland's state hospitals have only two months' supplies of AIDS drugs, the country's health minister has told parliament in an assessment that AIDS patients and activists took as a death sentence," the Associated Press/Seattle Times reports. More than 60,000 Swazis receive antiretroviral medicine at no cost from state-run hospitals.

30 Jun 2011

Study provides novel information about clinical potential of anti-cancer antibiotics

Most of us have had a doctor prescribe an antibiotic for a stubborn bacterial infection, or for a cut that gets infected. However, prescribing an antibiotic to fight cancer? In fact, anti-cancer antibiotics have been used since the 1950s to successfully treat several forms of cancer, but often the side effects limit the duration they can be given to a patient.

30 Jun 2011

NLST: CT screening reduces lung cancer specific mortality by 20%

Current and former heavy smokers can now be screened more effectively for lung cancer. Results from the National Lung Screening Trial (NLST) revealed that detecting small lung cancers with computed tomography (CT) reduces lung cancer specific mortality by 20 percent.

30 Jun 2011

Serum-free media with growth factors can improve MSCs' cell fate regulation

Mensenchymal stem cells (MSCs), multipotent cells identified in bone marrow and other tissues, have been shown to be therapeutically effective in the immunosuppression of T-cells, the regeneration of blood vessels, assisting in skin wound healing, and suppressing chronic airway inflammation in some asthma cases.

30 Jun 2011