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Copper enhances progression of Alzheimer's disease

Copper appears to be one of the main environmental factors that trigger the onset and enhance the progression of Alzheimer's disease by preventing the clearance and accelerating the accumulation of toxic proteins in the brain. That is the conclusion of a study appearing today in the journal Proceedings of the National Academy of Sciences.

20 Aug 2013

Study: Gene that controls ageing process linked to cancer

A gene that helps control the ageing process by acting as a cell's internal clock has been linked to cancer by a major new study.

19 Aug 2013

Calcium and vitamin D supplements have no effect on joint symptoms in postmenopausal women

A team of investigators systematically analyzed the effect of calcium and vitamin D supplementation on joint symptoms in a rigorous and controlled study of postmenopausal women. They found that supplementation did not reduce the severity of joint symptoms reported by the participants.

17 Aug 2013

ATSP-7041 stapled peptide activates p53, suppresses tumor growth in animal models

Aileron Therapeutics, Inc., a clinical stage biopharmaceutical company that is developing first-in-class therapeutics based on its proprietary Stapled Peptide drug platform, announced today the publication of preclinical data on ATSP-7041, a potent and selective stapled peptide re-activator of the wild type p53 tumor suppressor protein.

17 Aug 2013

Study: Herniated discs result from avulsion of tissue, rather than rupture

Herniated discs in the lower (lumbar) spine most often result from avulsion (separation) of the tissue connection between the disc and spinal bone, rather than rupture of the disc itself, according to a study in Spine. The journal is published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health.

16 Aug 2013

Researchers provide support for potential importance of vitamin D in pregnancy

Researchers at the MRC Lifecourse Epidemiology Unit, University of Southampton, have demonstrated that the degree to which a gene related to vitamin D action is switched on or off, when measured at birth, predicts bone density of the child at four years of age.

16 Aug 2013

Joint symptoms in postmenopausal women not reduced by calcium and vitamin D supplements

A team of investigators systematically analyzed the effect of calcium and vitamin D supplementation on joint symptoms in a rigorous and controlled study of postmenopausal women.

16 Aug 2013

Repair of sciatic nerve defects using tissue engineered nerves

Peripheral nerve defects are very common in clinical surgery. For repair of short-segment nerve defects, freeing nerve, nerve diversions or joint flexion can be used to directly connect the two stumps of nerves by using microsurgical techniques; while for long-segment nerve defects, we require a bridging material to bridge defected nerves.

16 Aug 2013

Osteoarthritis research: an interview with Dr Deborah Mason, Cardiff University

Osteoarthritis is an extremely common condition affecting about 8 million people in the UK. The elderly are particularly susceptible, with up to 45% of people over 65 years, having the disease.

14 Aug 2013

Johns Hopkins expert says crucial ethics should be considered in HIV cure research

A cure for HIV infection - the International AIDS Society meeting in Kuala Lumpur in early July offered new hope of the possibility, after researchers announced that two "Boston patients" had shown no resurgence of the virus after receiving a bone marrow transplant and ceasing their antiretroviral therapy (ART).

14 Aug 2013

Proton therapy provides organ-sparing treatment option for children with neuroblastoma

Proton therapy, using high-energy subatomic particles, may offer a precise, organ-sparing treatment option for children with high-risk forms of neuroblastoma. For patients in a new study of advanced radiation treatment, proton therapy spared the liver and kidneys from unwanted radiation, while zeroing in on its target.

14 Aug 2013

NIH awards $17M to research projects to investigate emerging field of exRNA

The National Institutes of Health announced today it will award $17 million this year for 24 research projects designed to improve scientists' understanding of a newly discovered type of cell-to-cell communication based on extracellular (outside the cell) RNA, also called exRNA.

14 Aug 2013

Study reports high survival rates for children with rare subtype of leukaemia

A pioneering genetic study means that children with a rare subtype of leukaemia have 75% less chance of their leukaemia recurring.

13 Aug 2013

Preclinical study reveals pomalidomide shows promising results for treatment of CNS lymphoma

A drug recently approved for use in multiple myeloma is now being tested for its ability to fight central nervous system (CNS) lymphoma, a deadly cancer of the immune system that can affect the brain, spinal cord and fluid, and eyes.

13 Aug 2013

Harvard University receives grant to use organs-on-chips device to test human response to radiation

A team at the Wyss Institute for Biologically Inspired Engineering at Harvard University has received a $5.6 million grant award from the United States Food and Drug Administration (FDA) to use its Organs-on-Chips technology for a novel application of keen interest to national security and health officials: to test human physiological responses to radiation, and to evaluate drugs designed to counter those effects.

13 Aug 2013

Doctor offers tips on how to talk with your tween about puberty

Some parents may shy away from talking to their daughters about puberty, but Loyola University Health System obstetrician and gynecologist Akua Afriyie-Gray, MD, stresses the importance of sitting down with your tween when the time comes.

13 Aug 2013

NW Bio receives decision to continue Phase III clinical trial on brain cancer in Germany

Northwest Biotherapeutics (NASDAQ: NWBO)(NW Bio), a biotechnology company developing non-toxic DCVax® personalized immune therapies for solid tumor cancers, announced today that it has received a decision from the German regulatory agency (the Paul Ehrlich Institute, or PEI) under which the Company's Phase III clinical trial will be able to proceed in Germany after the Company makes three modifications, none of which affect the body of the trial or the bases for seeking product approval.

12 Aug 2013

Researchers discover new treatment for children with fragile bone disease

A new treatment for children with brittle bone disease has been developed by the University of Sheffield and Sheffield Children's Hospital.

12 Aug 2013

Celgene's pomalidomide gets approval in UK for multiple myeloma

Celgene confirmed today that Pomalidomide Celgene▼ (pomalidomide), a new oral blood cancer therapy, has been granted Marketing Authorisation by the European Medicines Agency and is now available in the UK and Ireland.

9 Aug 2013

New reagent kits for intracellular staining from Beckman Coulter Life Sciences

PerFix-Expose1 and PerFix-nc1, innovative new reagent kits for intracellular staining from Beckman Coulter Life Sciences, minimize sample manipulation for a streamlined workflow that delivers high quality results. Developed for use on Beckman Coulter’s Gallios1 and Navios2 series flow cytometers and compatible with all Beckman Coulter Life Sciences’ fluorochromes, the kits enable a clear focus on the cytoplasmic and nuclear compartments of the cell.

8 Aug 2013

Bone News and Research

Copper enhances progression of Alzheimer's disease

Study: Gene that controls ageing process linked to cancer

Calcium and vitamin D supplements have no effect on joint symptoms in postmenopausal women

ATSP-7041 stapled peptide activates p53, suppresses tumor growth in animal models

Study: Herniated discs result from avulsion of tissue, rather than rupture

Researchers provide support for potential importance of vitamin D in pregnancy

Joint symptoms in postmenopausal women not reduced by calcium and vitamin D supplements

Repair of sciatic nerve defects using tissue engineered nerves

Osteoarthritis research: an interview with Dr Deborah Mason, Cardiff University

Johns Hopkins expert says crucial ethics should be considered in HIV cure research

Proton therapy provides organ-sparing treatment option for children with neuroblastoma

NIH awards $17M to research projects to investigate emerging field of exRNA

Study reports high survival rates for children with rare subtype of leukaemia

Preclinical study reveals pomalidomide shows promising results for treatment of CNS lymphoma

Harvard University receives grant to use organs-on-chips device to test human response to radiation

Doctor offers tips on how to talk with your tween about puberty

NW Bio receives decision to continue Phase III clinical trial on brain cancer in Germany

Researchers discover new treatment for children with fragile bone disease

Celgene's pomalidomide gets approval in UK for multiple myeloma

New reagent kits for intracellular staining from Beckman Coulter Life Sciences

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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