Protein C News and Research

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Protein kinase CK2 controls CD8+ T cell effector and memory functions during Listeria infection

The protein kinase CK2 is involved in a wide range of biological processes and cellular functions, including inflammatory responses and pathologies associated with inflammation.

1 Nov 2022

Researchers unravel how the brain chemical dopamine relates to schizophrenia

Researchers at the Lieber Institute for Brain Development (LIBD) believe they have solved a riddle that has challenged scientists for more than 70 years: how the brain chemical dopamine relates to schizophrenia, the often-devastating brain disorder characterized by delusional thinking, hallucinations and other forms of psychosis.

1 Nov 2022

Single-nucleus RNA sequencing and spatial transcriptome atlas of COVID-19 livers

Researchers performed single-nucleus RNA sequencing (snRNA-seq) and spatial transcriptomic profiling of livers from deceased coronavirus disease 2019 (COVID-19) patients.

1 Nov 2022

Researchers find the root of immunosuppression and chemoresistance in TNBC tumors

Triple-negative breast cancer (TNBC) tumors gain immunosuppression and chemoresistance through interactions between interleukin 34 and myeloid-derived suppressor cells, researchers find.

1 Nov 2022

WHO’s TAG-VE group present the most recent evidence on Omicron sublineages BQ.1 and XBB

WHO’s TAG-VE group presented the most recent evidence on Omicron evolution and genetic diversity.

1 Nov 2022

Hybrid virus particles formed from coinfections exhibit immune evasion and expanded tropism

Researchers examined virus-virus interactions using human lung cells coinfected with two co-circulating respiratory infection-causing viruses, respiratory syncytial virus (RSV) and influenza A virus (IAV).

1 Nov 2022

How does the ISG15/ISGylation system modulate Vaccinia virus infection?

Researchers demonstrated how interferon-stimulated gene 15 (ISG15) is involved in the Vaccinia virus (VACV) dissemination.

1 Nov 2022

Researchers fabricate cerebral cortical tissues in 3D and functionally integrate them into a brain lesion in mice

Researchers fabricated cerebral cortical tissues in 3D and functionally integrated them into a brain lesion in mice.

1 Nov 2022

Researchers take a cue from viruses to make glioblastoma more vulnerable to treatment

In the tough war against glioblastoma, scientists are taking a cue from viruses on how to make the aggressive cancer more vulnerable to treatment.

1 Nov 2022

People who had COVID-19 are more vulnerable to developing neurological symptoms

Research led by The University of Queensland has found COVID-19 activates the same inflammatory response in the brain as Parkinson's disease.

1 Nov 2022

Study expands breast cancer patient population that can benefit from PARP inhibitors

A drug approved to treat breast cancer patients with mutations in the BRCA1 or BRCA2 genes may also benefit people who have other genetic mutations.

31 Oct 2022

Polygenic hazard score could be effective for predicting genetic risk of lethal prostate cancer

Tapping into the Million Veteran Program, an ongoing national research effort to learn how genes, lifestyle and military exposures affect the health of participants, researchers at University of California San Diego School of Medicine and the VA San Diego Healthcare System, with colleagues elsewhere, report that a polygenic hazard score based on 290 genetic variants could be an effective tool for predicting genetic risk of lethal prostate cancer.

31 Oct 2022

Johns Hopkins researchers uncover a possible target to treat sleep apnea

In a new study with obese mice, Johns Hopkins Medicine researchers say they have added to evidence that specialized channel proteins are possible therapeutic targets for sleep apnea and similar abnormally slow breathing disorders in obese people.

31 Oct 2022

Most adults seeking to lose weight overestimate the healthiness of their diet

In a small study, most adults seeking to lose weight overestimated the healthiness of their diet, according to preliminary research to be presented at the American Heart Association's Scientific Sessions 2022.

31 Oct 2022

New research suggests booster dose of Novavax NVX-CoV2373 vaccine is effective against SARS-CoV-2 Omicron subvariants

A new study evaluated the neutralizing antibody titers against the SARS-CoV-2 Omicron variant and its sub-lineages after two and three doses of the Novavax protein nanoparticle vaccine NVX-CoV2373.

31 Oct 2022

Properties of dense breasts promote cancer growth, study suggests

The risk of developing breast cancer is higher in what are known as dense breasts, which appear white in mammograms, than in nondense breasts, which appear grey.

31 Oct 2022

Ubiquigent obtains exclusive license for UbiSite technology to strengthen its specialist drug discovery services

Ubiquigent Limited (Ubiquigent), a drug discovery and development company harnessing novel deubiquitylase (DUB) modulators as new therapeutics for areas of high unmet medical need, has signed an exclusive license with the University of Southern Denmark for its UbiSite® technology.

31 Oct 2022

Protein C News and Research

Protein kinase CK2 controls CD8+ T cell effector and memory functions during Listeria infection

Researchers unravel how the brain chemical dopamine relates to schizophrenia

Single-nucleus RNA sequencing and spatial transcriptome atlas of COVID-19 livers

Researchers find the root of immunosuppression and chemoresistance in TNBC tumors

WHO’s TAG-VE group present the most recent evidence on Omicron sublineages BQ.1 and XBB

Hybrid virus particles formed from coinfections exhibit immune evasion and expanded tropism

How does the ISG15/ISGylation system modulate Vaccinia virus infection?

Researchers fabricate cerebral cortical tissues in 3D and functionally integrate them into a brain lesion in mice

Researchers take a cue from viruses to make glioblastoma more vulnerable to treatment

People who had COVID-19 are more vulnerable to developing neurological symptoms

Study expands breast cancer patient population that can benefit from PARP inhibitors

Polygenic hazard score could be effective for predicting genetic risk of lethal prostate cancer

Johns Hopkins researchers uncover a possible target to treat sleep apnea

Most adults seeking to lose weight overestimate the healthiness of their diet

New research suggests booster dose of Novavax NVX-CoV2373 vaccine is effective against SARS-CoV-2 Omicron subvariants

Properties of dense breasts promote cancer growth, study suggests

Ubiquigent obtains exclusive license for UbiSite technology to strengthen its specialist drug discovery services

What is the impact of SARS-CoV-2 on HIV-1 infectivity?

Italian study evaluates COVID-19 reinfection risk among previously infected and vaccinated individuals

Does maternal obesity impact fetal brain development?

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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