Endocrine News and Research

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The interrelationship between diet, physical health, and depression

A recent Journal of Affective Disorders study examined the interrelationship between diet, physical health, and depression.

4 Jan 2023

Traditional Chinese medicine may help treat neurodegenerative diseases caused by HSV-1 reactivation

Announcing a new publication for Acta Materia Medica journal. Owing to environmental and lifestyle changes in modern society, physical and mental stress is on the rise among the population in attempting to compensate for the changes.

3 Jan 2023

Insilico announces nomination of preclinical candidate targeting KAT6A for ER+/HER2- breast cancer therapy

Insilico Medicine ("Insilico"), a clinical-stage end-to-end artificial intelligence (AI)-driven drug discovery company, today announced that the company's drug discovery team has nominated a preclinical candidate targeting KAT6A for ER+/HER2- breast cancer therapy utilizing its end-to-end Pharma.AI platform.

27 Dec 2022

Simple Corsi-Rosenthal boxes can help reduce exposure to indoor air pollutants

A team of researchers from Brown University's School of Public Health, Brown's School of Engineering and Silent Spring Institute found that simple air filtration devices called Corsi-Rosenthal boxes are effective at reducing indoor air pollutants.

23 Dec 2022

PCOS increases risk of pancreatic cancer

A new study in confirms that a history of polycystic ovarian syndrome increases a patient’s risk of developing pancreatic cancer.

21 Dec 2022

Experts provide first framework for treating hypercalcemia of malignancy in adults

Experts provide the first framework for treating a common and life-threatening metabolic complication of cancer known as hypercalcemia of malignancy in the Endocrine Society's new Clinical Practice Guideline.

21 Dec 2022

Data mining approaches for the detection of signals associated with pediatric post-acute sequelae of COVID-19

Researchers described tree-based scan statistics for pediatric long COVID-19.

16 Dec 2022

Intermittent fasting diet intervention may help patients to achieve complete diabetes remission

After an intermittent fasting diet intervention, patients achieved complete diabetes remission, defined as an HbA1c (average blood sugar) level of less than 6.5% at least one year after stopping diabetes medication, according to a new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism.

15 Dec 2022

Vitamin D levels for population in the Mediterranean area are not sufficiently analyzed, researchers say

Vitamin D is a hormone that is essential to a number of bodily processes, mainly absorbing and maintaining calcium, which is key for strong bones, but it also plays a role in inflammation processes, the immune system, cell growth and the metabolism.

14 Dec 2022

People with daily step count of 10,700 are 44% less likely to develop type 2 diabetes

Wearable fitness devices offer new insights into the relationship between physical activity and type 2 diabetes, according to a new analysis of the National Institutes of Health's All of Us Research Program data published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism.

13 Dec 2022

Vitamin D supplements reduce the risk of dynapenia in older people by 78%

Vitamin D plays an important role in the regulation of calcium and phosphorus absorption by the organism.

13 Dec 2022

Addition of capivasertib to fulvestrant doubles progression-free survival in HR-positive breast cancer patients

In patients with hormone receptor (HR)-positive, HER2-negative tumors resistant to aromatase inhibitors, addition of the investigational AKT inhibitor capivasertib to fulvestrant (Faslodex) doubled the median progression-free survival compared with placebo plus fulvestrant in the phase III CAPItello-291 clinical trial, according to results presented at the San Antonio Breast Cancer Symposium, held December 6-10, 2022.

9 Dec 2022

POLAR gene profile predicts which patients may and may not benefit from radiation therapy after breast-conserving surgery

Patients with invasive breast cancer who had low scores on an investigational gene molecular signature had similar rates of local recurrence whether or not they received adjuvant radiation therapy after breast-conserving surgery, according to results of a meta-analysis presented at the San Antonio Breast Cancer Symposium, held December 6-10, 2022.

9 Dec 2022

Study reveals how the HOXA5 gene may work to suppress breast cancer formation

Researchers at the Johns Hopkins Kimmel Cancer Center have revealed how the gene HOXA5 may work to suppress formation of breast cancers.

8 Dec 2022

Trial establishes the clinical utility of circulating tumor cell count as biomarker in breast cancer care

The use of circulating tumor cell (CTC) count to guide the choice between chemotherapy and endocrine therapy as first-line therapy for patients with metastatic, estrogen receptor (ER)-positive/HER2-negative breast cancer provided overall survival benefit, compared with physician's choice of treatment, according to data from the STIC CTC trial presented at the San Antonio Breast Cancer Symposium, held December 6-10, 2022.

8 Dec 2022

Updated results on a new approach to treating advanced ER-positive/HER2-negative breast cancer

A UCLA Jonsson Comprehensive Cancer Center researcher and collaborators in a multicenter study will present updated results and plans for further research on a new approach to treating advanced ER-positive/HER2-negative breast cancer.

7 Dec 2022

New Clinical Practice Guideline offers recommendations to manage hypoglycemia in people with diabetes

People with diabetes are benefiting from advances in medications and technologies to lower their risk of hypoglycemia, according to a Clinical Practice Guideline issued today by the Endocrine Society.

7 Dec 2022

Genomic assay can help identify breast cancer patients who may benefit from ovarian suppression therapy

Among premenopausal women with hormone receptor (HR)-positive, early-stage breast cancer enrolled in the SOFT trial, those with a high score on a genomic assay called Breast Cancer Index (BCI) had increased risk of distant recurrence, and those with low BCI benefited more from the addition of ovarian suppression therapy to endocrine therapy after 12 years of follow-up, according to data presented at the San Antonio Breast Cancer Symposium, held December 6-10, 2022.

7 Dec 2022

Machine learning analysis suggests that there are four sub-phenotypes of long COVID

Researchers identified PASC [post-acute sequelae of coronavirus disease 2019 (COVID-19)] sub-phenotypes depending on conditions diagnosed within 1 to 3 months of acute infection by SARS-CoV-2.

6 Dec 2022

UHN’s Ajmera Transplant Centre performed a groundbreaking parathyroid transplant

The Ajmera Transplant Centre at University Health Network (UHN) has performed a groundbreaking parathyroid transplant, in a patient who suffered from a severe form of hypoparathyroidism – when there is little or no parathyroid function.

5 Dec 2022

Endocrine News and Research

The interrelationship between diet, physical health, and depression

Traditional Chinese medicine may help treat neurodegenerative diseases caused by HSV-1 reactivation

Insilico announces nomination of preclinical candidate targeting KAT6A for ER+/HER2- breast cancer therapy

Simple Corsi-Rosenthal boxes can help reduce exposure to indoor air pollutants

PCOS increases risk of pancreatic cancer

Experts provide first framework for treating hypercalcemia of malignancy in adults

Data mining approaches for the detection of signals associated with pediatric post-acute sequelae of COVID-19

Intermittent fasting diet intervention may help patients to achieve complete diabetes remission

Vitamin D levels for population in the Mediterranean area are not sufficiently analyzed, researchers say

People with daily step count of 10,700 are 44% less likely to develop type 2 diabetes

Vitamin D supplements reduce the risk of dynapenia in older people by 78%

Addition of capivasertib to fulvestrant doubles progression-free survival in HR-positive breast cancer patients

POLAR gene profile predicts which patients may and may not benefit from radiation therapy after breast-conserving surgery

Study reveals how the HOXA5 gene may work to suppress breast cancer formation

Trial establishes the clinical utility of circulating tumor cell count as biomarker in breast cancer care

Updated results on a new approach to treating advanced ER-positive/HER2-negative breast cancer

New Clinical Practice Guideline offers recommendations to manage hypoglycemia in people with diabetes

Genomic assay can help identify breast cancer patients who may benefit from ovarian suppression therapy

Machine learning analysis suggests that there are four sub-phenotypes of long COVID

UHN’s Ajmera Transplant Centre performed a groundbreaking parathyroid transplant

Improving healthcare sustainability through carbon data

Managing vibration in IVF laboratories

A New Approach to Preventing Bladder Cancer Recurrence

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