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Oxford University and AstraZeneca vaccine against SARS-CoV-2 safe and induces immune response

Promising early stage results from a phase 1/2 clinical trial of the UK's vaccine candidate against SARS-CoV-2 (the virus that causes COVID-19) are published today in The Lancet.

20 Jul 2020

Study shows feasibility of using cardiovascular risk screening tool in outpatient gynecology setting

A new study has shown that although 86% of women seen at an outpatient gynecology clinic had a cardiovascular risk factor and 40.1% had at least one cardiovascular symptom, the awareness of cardiovascular risk factors and symptoms was low.

20 Jul 2020

Oxford University and AstraZeneca to publish eagerly-anticipated COVID-19 trial results today

The coronavirus pandemic is still rapidly spreading across the globe, infecting more than 14.44 million people. With more than 188 countries and territories affected, scientists are racing to develop a vaccine against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus that causes the coronavirus disease (COVID-19).

19 Jul 2020

Newly identified enzyme provides a new tool in CRISPR genome editing toolbox

A recently discovered hypercompact CRISPR enzyme found only in huge bacteriophages, and known as CRISPR-CasΦ, is functional, a new study by Patrick Pausch, Jennifer Doudna and colleagues reports, and it provides a powerful new tool in the CRISPR genome editing toolbox, including because it can target a wider range of genetic sequences compared to Cas9 and Cas12.

17 Jul 2020

Study identifies brain circuitry that plays key role in ASD-relevant behaviors

A team led by UT Southwestern researchers has identified brain circuitry that plays a key role in the dysfunctional social, repetitive, and inflexible behavioral differences that characterize autism spectrum disorders (ASD).

15 Jul 2020

Biological anti-tumor mechanism can provide long-term immune response against tumors

Blocking a newly identified "immune memory checkpoint" in immune cells could improve immunotherapy and help prevent cancers from recurring, according to new findings in mice and human samples by researchers at the UPMC Hillman Cancer Center and the University of Pittsburgh School of Medicine.

15 Jul 2020

Study could help determine motor abilities that are difficult to recover after traumatic brain injury

After a traumatic brain injury, why do some people quickly regain their skills while others face long-lasting setbacks? Boston University neuroscientist Jerry Chen and his colleagues have been trying to answer this question by understanding which parts of the brain are used to process sensory information and remember different skills.

10 Jul 2020

New discovery helps explain heart defects in Barth syndrome

The heart needs energy to pump blood. So, energy production defects in heart muscles result in a variety of cardiac diseases.

7 Jul 2020

Researchers use nanoparticles to deliver gene therapy for blinding eye disease

In experiments in rats and mice, two Johns Hopkins scientists - an engineer and an ophthalmologist - report the successful use of nanoparticles to deliver gene therapy for blinding eye disease.

7 Jul 2020

Study reveals key role of a protein in regulating scar tissue growth after heart attacks

New UCLA research conducted in mice could explain why some people suffer more extensive scarring than others after a heart attack.

6 Jul 2020

New editorial published following adverse events of gene therapy clinical trial

The Editor-in-Chief of Human Gene Therapy, the first journal devoted to the field of gene therapy, and one of the world's leading experts on gene therapy have co-authored a new editorial, Moving Forward After Two Deaths in a Gene Therapy Trial of Myotubular Myopathy, in response to the news of two deaths in a now-halted gene therapy clinical trial.

3 Jul 2020

Researchers discover new candidate for raw material synthesis through gene transfer

Cyanobacteria hardly need any nutrients and use the energy of sunlight. Bathers are familiar with these microorganisms - often incorrectly called "blue-green algae" - as they often occur in waters.

2 Jul 2020

New technology can increase the quality of stem cells used in regenerative medicine

Stem cells have been holding great promise for regenerative medicine for years. In the last decade, several studies have shown that this type of cell, which in Spanish is called "mother cell" because of its ability to give rise to a variety of different cell types, can be applied in regenerative medicine for diseases such as muscular and nervous system disorders, among others.

2 Jul 2020

Researchers discover a protein that protects B cells from stress-induced cell death

Whenever a germ gets into the human body, the immune system usually responds immediately to fight off the enemy attacker. One of our defense system's most important strategies involves B lymphocytes, also known as B cells, which produce antibodies that target and neutralize pathogens.

1 Jul 2020

New vaccination strategy targets toxic molecules released by all Staphylococcal bacteria

Experiments in mice have shown early success in vaccinating them against potentially deadly bacterial infections, such as methicillin-resistant Staphylococcal aureus, or MRSA, the strain resistant to most drug treatments.

30 Jun 2020

Blocking a pair of sugar-transporting proteins impairs lung tumor growth

Blocking a pair of sugar-transporting proteins may be a useful treatment approach for lung cancer, suggests a new study in mice and human cells published today in eLife.

23 Jun 2020

Hungarian physician to receive the Körber Prize for European Science 2020

The Körber Prize for European Science 2020, which is endowed with one million euros, is being awarded to the Hungarian physician Botond Roska.

23 Jun 2020

Defective maintenance puts intestinal health in danger

In order to keep the intestinal mucosa and the entire organism healthy, intestinal epithelial cells have developed various protective functions involving a number of maintenance mechanisms that protect cells from stress.

23 Jun 2020

Researchers discover key protein that can reduce damage caused by heart attack

In a heart attack, a series of biochemical processes leave the heart damaged, much like a car after an accident.

23 Jun 2020

New method for producing tsetse fly attractants using biotechnology

The tsetse fly occurs in large regions of sub-Saharan Africa. The flies feed on human and animal blood, transmitting trypanosoma in the process - small, single-cell organisms that use the flies as intermediate host and cause a dangerous inflammation of the lymph and nervous system in both animals and humans.

22 Jun 2020

Genetic Engineering News and Research

Oxford University and AstraZeneca vaccine against SARS-CoV-2 safe and induces immune response

Study shows feasibility of using cardiovascular risk screening tool in outpatient gynecology setting

Oxford University and AstraZeneca to publish eagerly-anticipated COVID-19 trial results today

Newly identified enzyme provides a new tool in CRISPR genome editing toolbox

Study identifies brain circuitry that plays key role in ASD-relevant behaviors

Biological anti-tumor mechanism can provide long-term immune response against tumors

Study could help determine motor abilities that are difficult to recover after traumatic brain injury

New discovery helps explain heart defects in Barth syndrome

Researchers use nanoparticles to deliver gene therapy for blinding eye disease

Study reveals key role of a protein in regulating scar tissue growth after heart attacks

New editorial published following adverse events of gene therapy clinical trial

Researchers discover new candidate for raw material synthesis through gene transfer

New technology can increase the quality of stem cells used in regenerative medicine

Researchers discover a protein that protects B cells from stress-induced cell death

New vaccination strategy targets toxic molecules released by all Staphylococcal bacteria

Blocking a pair of sugar-transporting proteins impairs lung tumor growth

Hungarian physician to receive the Körber Prize for European Science 2020

Defective maintenance puts intestinal health in danger

Researchers discover key protein that can reduce damage caused by heart attack

New method for producing tsetse fly attractants using biotechnology

eBook: Using iPSCs models for human disease research and drug discovery eBook

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