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Inhibition of mitochondrial calcium uptake specifically toxic to cancer cells

Inhibiting the transfer of calcium ions into the cell's powerhouse is specifically toxic to cancer cells, according to an article published this week in Cell Reports by researchers from the Perelman School of Medicine at the University of Pennsylvania.

4 Mar 2016

Twitter may be effective, untapped resource to boost patient enrollment in cancer clinical trials

Twitter may be an effective, untapped resource to stimulate interest in cancer clinical trials and boost enrollment, physicians at the Abramson Cancer Center of the University of Pennsylvania suggest in a new research letter in JAMA Oncology. Analyzing thousands of lung cancer tweets on the social media site revealed that a surprisingly large number were about clinical trials, particularly ones on immunotherapy, although none were used for recruitment.

4 Mar 2016

End-of-life care can be challenging for people behind bars

With an increasingly aging prison population, end-of-life care for inmates is becoming a more prominent issue, according to Penn State nursing researchers. End-of-life -- EOL -- care can be complicated, no matter who the patient is, but can be especially challenging for those behind bars.

27 Feb 2016

ResMed announces definitive agreement to acquire Brightree

ResMed, the world's leading tech-driven medical device company and innovator in sleep-disordered breathing and respiratory care, today announced a definitive agreement to acquire privately held Brightree, a leader in business management and clinical software applications for the post-acute care industry.

From ResMed Corp 22 Feb 2016

Regular DBT imaging can increase cancer detection and reduce call backs

The increased cancer detection and reduced call backs associated with 3D mammography, also known as Digital Breast Tomosynthesis (DBT), can be maintained years after a patient's first DBT screening with regularly scheduled DBT imaging, according to a JAMA Oncology study published online today from researchers at the Perelman School of Medicine at the University of Pennsylvania.

19 Feb 2016

Testosterone treatment for older men improves sexual function, walking ability and mood

As men age, their testosterone levels decrease, but prior studies of the effects of administering testosterone to older men have been inconclusive. Now, research shows that testosterone treatment for men over 65 improves sexual function, walking ability and mood, according to a study published in the New England Journal of Medicine by team researchers from the Perelman School of Medicine at the University of Pennsylvania, and twelve other medical centers in the United States, in partnership with the National Institute on Aging.

18 Feb 2016

Heart attack patients experiencing cardiogenic shock at higher risk of death in first 60 days post-discharge

Heart attack patients who experience cardiogenic shock have a higher risk of death or rehospitalization than non-shock patients in the first 60 days post-discharge, but by the end of the first year, the gap between the two groups narrows, according to a study published today in the Journal of the American College of Cardiology.

16 Feb 2016

Barbara Ann Karmanos Cancer Institute recognized as one of America's Best Hospitals for Cancer Care

The Barbara Ann Karmanos Cancer Institute has received the 2016 Women's Choice Award as one of America's Best Hospitals for Cancer Care for the third consecutive year. Karmanos also received the award in 2011 and 2012, as well as 2014 and 2015.

12 Feb 2016

Study looks at post-treatment resources for prostate cancer patients transitioning to survivorship

The System Partner of Rutgers Cancer Institute of New Jersey, Meridian Health is joining forces with Rutgers Cancer Institute in offering access to a research study aimed at prostate cancer patients who are transitioning to survivorship.

11 Feb 2016

Enhancing quality of life for people with serious illnesses

Being diagnosed with a potentially life-threatening illness is distressing enough but a dearth of cohesive services often compounds the difficulty, according to an NAU researcher.

11 Feb 2016

Penn investigators devise new method to map 'transcriptome'

A new way of mapping the "transcriptome" -- the collection of RNA read-outs that are expressed by a cell's active genes -- has been devised by researchers from the Perelman School of Medicine at the University of Pennsylvania.

10 Feb 2016

Study shows how structural differences in the brain may relate to behavior differences in males and females

Differences in the neural wiring across development of men and women across ages, matched behavioral differences commonly associated with each of the sexes, according to an imaging-based study from researchers at the Perelman School of Medicine at the University of Pennsylvania published February 1 in Philosophical Transactions of the Royal Society B.

10 Feb 2016

LouLou Foundation, Penn Med set up Program of Excellence to develop treatments for children with CDKL5

The London-based LouLou Foundation and the Orphan Disease Center of the Perelman School of Medicine at the University of Pennsylvania have established a Program of Excellence to develop effective treatments for children with CDKL5, a rare X-chromosome-linked genetic disorder that causes severe neuro-developmental impairment and early-onset, difficult-to-control seizures.

8 Feb 2016

American Diabetes Association issues statement to address diabetes management in LTC facilities

The care of adults over age 65 with type 2 diabetes is a growing concern: the prevalence of diabetes is highest in this age group and is expected to grow as the U.S. population ages, with many needing care at long-term care (LTC) facilities.

3 Feb 2016

Critical access hospitals help meet need for high-quality palliative care in rural communities

Nurses at critical access hospitals are well positioned to provide high-quality palliative care close to home for millions of Americans in rural communities, according to an article in the February issue of Critical Care Nurse.

2 Feb 2016

New Penn study examines differences in costs of end-of-life care among developed countries

Despite widespread perception, the United States does not provide the worst end-of-life care in the world. In the first international comparison of end-of-life care practices, researchers from the Perelman School of Medicine at the University of Pennsylvania and colleagues from seven countries found that the United States actually has the lowest proportion of deaths in the hospital and the lowest number of days in the hospital in the last six months of life among the those countries, according to a new study published today in JAMA.

20 Jan 2016

New recommendations to reduce radiation-induced breast cancer risk from digital mammography

Radiation-induced breast cancer risk from digital mammography is low for the majority of women, but risk is higher in women with large breasts, who received 2.3 times more radiation and required more views per examination to image as much of the breast as possible compared to those with small or average-sized breasts.

18 Jan 2016

Penn study provides new insight into cause of peripartum cardiomyopathy in pregnant women

Each year approximately 1 in 1,000 pregnant women will experience peripartum cardiomyopathy, an uncommon form of often severe heart failure that occurs in the final month of pregnancy or up to five months following delivery. But the cause of peripartum cardiomyopathy has been largely unknown - until now.

7 Jan 2016

Typical premium-based financial incentives fail to promote weight loss among obese employees

Employers around the nation are increasingly searching for ways to help their employees make healthy lifestyle choices including encouraging obese employees to lose weight, often by offering financial incentives in the form of reduced health insurance premiums to help encourage success.

6 Jan 2016

New Penn study shows that social behavior in carpenter ants can be reprogrammed

In Florida carpenter ant colonies, distinct worker castes called minors and majors exhibit pronounced differences in social behavior throughout their lives. In a new study published today in Science, a multi-institution team anchored at University of Pennsylvania found that these caste-specific behaviors are not set in stone.

4 Jan 2016