Metastasis News and Research

RSS

Metastasis is the spread of cancer from one part of the body to another. A tumor formed by cells that have spread is called a “metastatic tumor” or a “metastasis.” The metastatic tumor contains cells that are like those in the original (primary) tumor. The plural form of metastasis is metastases

Study offers a combination treatment option for patients with oligometastatic prostate cancer

A new study offers a new option to patients with oligometastatic prostate cancer who want relief from hormone therapy without compromising the risk of their disease spreading.

25 Oct 2022

Clinical trial confirms the safety, efficacy of shortened radiation therapy for high-risk prostate cancer patients

A new randomized study confirms that men with high-risk prostate cancer can be treated with five versus eight weeks of radiation therapy.

24 Oct 2022

Salk's three collaborative projects win 2022 Curebound Discovery Grant

The Salk Institute's American Cancer Society Professor Tony Hunter, Professor Reuben Shaw, and Assistant Professor Graham McVicker are among 12 inaugural 2022 Discovery Grant winners.

19 Oct 2022

Rare insect-eating mushrooms show potential to develop new anti-viral and cancer medications

Scientists studying the medicinal potential of a rare insect-eating mushroom have found a way to grow the elusive fungi in the lab, opening the way for the development of new anti-viral and cancer medications.

19 Oct 2022

Common oral bacterium promotes tumor progression-associated activity in pancreatic cancer cells

Virginia Tech researchers from the Department of Biomedical Engineering and Mechanics and the Department of Biochemistry have discovered a characteristic of a common oral bacterium that relocates to pancreatic cancer tumors that may help guide future therapeutic interventions for treatment.

18 Oct 2022

Study reveals how a cell signaling molecule can help oral cancer cells acquire high motility

The process of metastasis is when cancer cells gain motility and spread to other sites of the body. Because this is one of the main causes of cancer-related deaths, researchers have aimed to develop therapeutic strategies that can block metastasis.

18 Oct 2022

UNO-peptide-modified CCN shows promise for targeted delivery of TAM immunomodulatory agents

Announcing a new publication for Acta Materia Medica journal. Tumor-associated macrophages (TAMs) are key contributors to tumor development, accelerated tumor invasion and metastasis, and induction of immunosuppression.

13 Oct 2022

Scientists discover a new drug-resistance mechanism in breast cancer

Scientists from Università Cattolica in Rome, together with colleagues from the IIGM Foundation (part of Candiolo Institute at Turin), have discovered a new drug-resistance mechanism in breast cancer that leads to the formation of cancer stem cells, (the cells that feed the tumor and cause relapse and metastasis).

6 Oct 2022

Discovery opens up new approaches to personalized treatment for small cell lung cancer

Small cell lung cancer is a particularly aggressive tumor, which has so far been treated with standardized measures.

6 Oct 2022

Fungal involvement in tumors may drive worse cancer outcomes

The presence of some fungal species in tumors predicts - and may even help drive - worse cancer outcomes, according to a study from Weill Cornell Medicine and Duke University researchers.

3 Oct 2022

Cancer cells 'hijack' a process used by healthy cells to spread around the body, research finds

Cancer Research UK-funded scientists have discovered that cancer cells 'hijack' a process used by healthy cells to spread around the body, completely changing current ways of thinking around cancer metastasis.

29 Sep 2022

uPAR may be a promising target for therapy in patients with neuroendocrine neoplasms

A novel PET radiotracer can accurately assess the presence of a biomarker that indicates the level of tumor aggressiveness in neuroendocrine neoplasms (NENs).

28 Sep 2022

Houston Methodist researchers receive CPRIT funding to research two of the most lethal cancers

Two Houston Methodist cancer researchers have been awarded a half million dollars in funding from the Cancer Prevention and Research Institute of Texas to further research two of the most lethal, difficult-to-treat cancers that all-too-often have poor prognoses.

28 Sep 2022

Novel PTP1B inhibitor drug candidate can prevent lethal lung inflammation in mice

Neutrophils, the most abundant type of white blood cell, are the body's first line of defense against infection. Foreign pathogens can stress the body and activate neutrophils.

23 Sep 2022

Common genetic variants of APOE associated with COVID mortality

It may be the most baffling quirk of COVID: What manifests as minor, flu-like symptoms in some individuals spirals into severe disease, disability, and even death in others.

21 Sep 2022

Is aspirin linked to higher rates of survival for cancer patients?

Researchers discussed the existing evidence on the use of acetylsalicylic acid (aspirin) in cancer treatment.

19 Sep 2022

Study highlights role of tumor-infiltrating B cells, plasma cells in cancer development and treatment outcomes

Through extensive single-cell analysis, researchers at The University of Texas MD Anderson Cancer Center have created a spatial map of tumor-infiltrating B cells and plasma cells in early-stage lung cancers, highlighting previously unappreciated roles these immune cells play in tumor development and treatment outcomes.

13 Sep 2022

Antibiotics accelerate metastatic bone growth in mice with melanoma by depleting intestinal flora

The use of broad-spectrum antibiotics in mice with malignant melanoma, an aggressive form of skin cancer, accelerated their metastatic bone growth, likely because the drugs depleted the mice's intestinal flora and weakened their immune response, according to a new study by researchers at Emory University in Atlanta.

12 Sep 2022

Neoadjuvant NHAs followed by surgery can improve key outcomes in high-risk prostate cancer patients

For high-risk patients with prostate cancer, treatment with novel hormonal agents (NHAs) followed by surgery can reduce the risk of recurrent and progressive cancer, compared to initial treatment with surgery, suggests a study in The Journal of Urology®, an Official Journal of the American Urological Association (AUA).