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Pepscan announces increased GMP production capacity to facilitate clients' growth

Today, Pepscan announced that its GMP production capacity has doubled. Pepscan is an all-in-one partner in peptides, building on 25 years of experience in advancing and applying peptide expertise to facilitate clients in the development and production of peptides.

9 Oct 2019

Study identifies genetic marker which could personalize treatment for Crohn's disease

The largest study ever to look at why an expensive and commonly used group of drugs fails some patients with Crohn's disease has identified a genetic marker which could individualize drug treatment.

7 Oct 2019

Common genetic variant explains why immunotherapy often fails in Crohn's disease

The reason why a commonly used range of immunotherapy drugs is not effective in some patients with Crohn’s disease has so far not been identified, until now.

7 Oct 2019

Monitoring the Human Proteome using diaPASEF

In this interview, Dr. Hannes Röst describes how his lab are using diaPASEF to monitor the human proteome throughout a person's lifetime, and how machine learning could be used to analyze the data.

From Bruker Daltonics 25 Sep 2019

New genetic test could help avoid unnecessary prostate cancer surgery

Men who develop prostate cancer could avoid having unnecessary surgery or radiotherapy thanks to a new, more precise genetic test which is being trialed in Leeds.

25 Sep 2019

Gene regulators work together to raise individual's risk of schizophrenia

Researchers have discovered that gene expression regulators work together to raise an individual's risk of developing schizophrenia.

23 Sep 2019

CRISPR may explain why so many experimental cancer drugs fail

Scientists have used CRISPR–Cas9 to investigate how ten cancer drugs interact with their protein target, revealing some intriguing findings.

13 Sep 2019

Simple genetic test may boost response rates in children with eosinophilic esophagitis

Personalized medicine - where the proper medicine and proper dose are used for the individual patient - moved a step closer to reality for children suffering from eosinophilic esophagitis, an inflammation of the food pipe often caused by an allergic reaction to certain foods.

12 Sep 2019

Mount Sinai researchers discover drug resistance signature in Crohn's disease

By mapping out more than 100,000 immune cells in patients with Crohn's disease, Mount Sinai researchers have discovered a signature of cells that are involved in a type of the disease that does not respond to treatment, according to a study published in Cell in August.

29 Aug 2019

Retina-on-a-chip may provide useful alternative to existing models for studying eye disease

The development of a retina-on-a-chip, which combines living human cells with an artificial tissue-like system, has been described today in the open-access journal eLife.

27 Aug 2019

Anxiety, depression associated with increased opioid use following surgery

Surgeons wielding their life-saving scalpels, laparoscopic tools, or other implements to repair or remove what ails their patients understand all too well that pain is an unavoidable part of the healing process. Yet the current opioid crisis has made the standard prescribing practices for these highly effective analgesics fraught with risk.

22 Aug 2019

Most patients willing to share personal medical data with researchers, survey finds

As medicine becomes both bigger and more personalized, the need for massive databases of patient records, such as the 1 million person All of Us Research Program, become increasingly essential to fueling both new discoveries and translational treatments.

21 Aug 2019

New insight into the immune system may help doctors to better fight cancer

Your immune system's natural killer cells recognize and attack two major kinds of danger - cells infected by viruses and cells affected by cancer.

20 Aug 2019

Mini kidneys grown in the lab could be used to better understand kidney diseases

An international team of researchers led by Nanyang Technological University, Singapore (NTU Singapore) has grown 'miniature kidneys' in the laboratory that could be used to better understand how kidney diseases develop in individual patients.

20 Aug 2019

Scientists demonstrate an in vitro kidney model

Kidneys work to constantly filter blood and remove toxins from the body. Conditions such as chronic kidney disease are characterized by a reduced ability to perform this essential function.

14 Aug 2019

Racial and ethnic disparities exist in palliative care use among hospitalized patients with ESKD

Striking racial and ethnic disparities exist in the use of palliative care by hospitalized patients with end-stage kidney disease on dialysis, researchers at the Icahn School of Medicine at Mount Sinai report. The findings were published today in Journal of the American Society of Nephrology.

8 Aug 2019

FDG-PET/CT may assist in surgical planning for head and neck cancer

The Journal of Clinical Oncology has published the results of the largest prospective multicenter trial conducted of FDG-PET/CT in head and neck cancer, providing rigorous data about its performance.

7 Aug 2019

Questionnaire-based algorithm predicts preeclampsia risk in pregnant woman

Research presented today at the 71st AACC Annual Scientific Meeting & Clinical Lab Expo shows that a questionnaire-based algorithm predicts the risk of a pregnant woman developing preeclampsia.

6 Aug 2019

Genetic and environmental factors play major roles in the onset of vitiligo

A pair of new journal articles by researchers at the University of Colorado School of Medicine indicate that both genetic and environmental factors play significant roles in the onset of vitiligo, an autoimmune disease that results in the loss of color in blotches of skin.

31 Jul 2019

Trial shows nor-urso as an effective treatment option for nonalcoholic fatty liver disease

A team led by Michael Trauner at MedUni Vienna's Division of Gastroenterology and Hepatology demonstrated the beneficial effect of synthetically produced bile acid with the active agent nor-ursodeoxycholic acid (nor-urso) in the hitherto incurable liver disease primary sclerosing cholangitis (PSC) around two years ago.

29 Jul 2019