Stem Cells News and Research

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Stem cells have the remarkable potential to develop into many different cell types in the body during early life and growth. In addition, in many tissues they serve as a sort of internal repair system, dividing essentially without limit to replenish other cells as long as the person or animal is still alive. When a stem cell divides, each new cell has the potential either to remain a stem cell or become another type of cell with a more specialized function, such as a muscle cell, a red blood cell, or a brain cell.

Aging immune system fuels cancer growth

A novel study by researchers at the Icahn School of Medicine at Mount Sinai addresses a critical yet under-explored question in cancer research: Why is aging the biggest risk factor for cancer? The study reveals how an aging immune system spurs tumor growth, offering new insights into cancer prevention and treatment, especially for older adults.

6 Sep 2024

Researchers seek to revolutionize neurological disease treatment through intelligent biocomputing

With newly awarded funding from the National Science Foundation, researchers at the University of California, Irvine and the Keck School of Medicine of USC will seek to revolutionize the treatment of neurological diseases through intelligent biocomputing.

5 Sep 2024

Investigating inflammatory memory in hematopoietic stem cells within the AML niche

A new research perspective was published in Oncotarget's Volume 15 on September 4, 2024, entitled, "Trained and ready - the case for an inflammatory memory for hematopoietic stem and progenitor cells in the AML niche."

5 Sep 2024

Scientists advance type 1 diabetes treatment with cutting-edge stem cell and gene editing technologies

Researchers review significant advancements and ongoing challenges in cell replacement therapies for type 1 diabetes, highlighting innovative approaches in stem cell-derived islets and immune protection strategies.

5 Sep 2024

Study reveals menstrual cycle’s role in spreading mutant cells in breast tissue

A team of researchers at the VIB-KU Leuven Center for Cancer Biology, the Netherlands Cancer Institute and Oncode Institute and the University of Cambridge have discovered that a defensive mechanism connected to the menstrual cycle plays a role in spreading mutant cells within mammary tissue.

4 Sep 2024

Astrocytes reprogrammed to brain stem cells through methylation

Resting brain stem cells hardly differ from normal astrocytes, which support the nerve cells in the brain.

4 Sep 2024

Review explores WNT5B and WNT10B roles in osteosarcoma

A new review was published in Oncotarget's Volume 15 on August 2, 2024, entitled, "Targeting WNT5B and WNT10B in osteosarcoma."

4 Sep 2024

Study uncovers key enzyme link between obesity and atrial fibrillation

A cellular link between obesity and atrial fibrillation - a heart condition that afflicts over 33 million people worldwide - presents a promising target for new therapies, researchers from the University of Illinois Chicago report.

4 Sep 2024

Allen Institute and NYSCF launch collaboration to create inclusive cellular models

Today, the Allen Institute for Cell Science and New York Stem Cell Foundation (NYSCF) announced a pioneering collaboration to address this critical issue, combining two cutting-edge technologies to create more inclusive cellular models for studying disease.

4 Sep 2024

Penn research uncovers key biomarker for diagnosing sarcoidosis

Sarcoidosis is a rare systemic disease that afflicts an estimated 200,000 people in the US, more often people who are Black and more women than men, particularly when it causes chronic skin disease.

3 Sep 2024

Study shows beta cells can function independently for glycemic control

Our glycemic balance is based on the ability of the pancreatic beta cells to detect glucose and secrete insulin to maintain our blood sugar levels. If these cells malfunction, the balance is broken, and diabetes develops.

3 Sep 2024

Clonal hematopoiesis drives femoral atherosclerosis in middle-aged adults

Researchers reveal that clonal hematopoiesis (CH) significantly increases the risk of developing femoral atherosclerosis, suggesting a unidirectional relationship independent of traditional cardiovascular risk factors.

2 Sep 2024

Breakthrough in blood stem cell development offers hope for leukemia and bone marrow failure

Melbourne researchers have made a world first breakthrough into creating blood stem cells that closely resemble those in the human body. And the discovery could soon lead to personalized treatments for children with leukemia and bone marrow failure disorders.

2 Sep 2024

Clonal hematopoiesis identified as new risk factor for atherosclerosis

To the known risk factors for cardiovascular disease - high blood pressure, high cholesterol, diabetes, overweight and obesity, smoking, and physical inactivity - a new one has to be added: clonal hematopoiesis.

30 Aug 2024

Redefining 5hmC: More than just a stepping stone in the DNA demethylation pathway

An important DNA modification is methylation, or the addition of a methyl group to the 5th carbon of cytosine. This forms 5-methylcytosine (5mC), typically associated with repression of gene expression.

From biomodal 30 Aug 2024

Study identifies genetic cause of severe seizures in children

Shortly after Kelly Cervantes' daughter Adelaide was born, she started having terrible seizures. Doctors were unable to give her a solution, or even a cause.

28 Aug 2024

Benefits of less intensive stem cell transplants for sickle cell disease

So-called low-intensity blood stem cell transplants, which use milder conditioning agents than standard stem cell transplants, do not appear to damage the lungs and may help improve lung function in some patients with sickle cell disease (SCD), according to a three-year study of adults who underwent the procedure at the National Institutes of Health (NIH).

28 Aug 2024

Zbtb18 regulates cKit expression for HSC self renewal

The study addresses the complex regulation of HSCs, highlighting p21's multifunctional nature beyond cell cycle control. Through the use of p21-tdTomato mice, researchers differentiate between p21-tdT+ and p21-tdT− HSCs. Results show that p21-tdT+ HSCs display increased self-renewal and reconstitution abilities. Zbtb18, upregulated in p21-tdT+ HSCs, is crucial for their repopulation capability. p21 interacts with ZBTB18 to suppress cKit, influencing HSC self-renewal.

28 Aug 2024

Artificial intelligence differentiates cancer cells and detects early viral infections

Researchers at the Centre for Genomic Regulation (CRG), the University of the Basque Country (UPV/EHU), Donostia International Physics Center (DIPC) and the Fundación Biofisica Bizkaia (FBB, located in Biofisika Institute) have developed an artificial intelligence which can differentiate cancer cells from normal cells, as well as detect the very early stages of viral infection inside cells.

27 Aug 2024

Stem cell study identifies unique glial contributions to multiple sclerosis

A team of scientists from The New York Stem Cell Foundation (NYSCF) Research Institute and Case Western Reserve University has created the largest reported collection of stem cell models from multiple sclerosis (MS) patients and used them to identify unique ways in which glia – integral support cells in the brain – contribute to the disease.

26 Aug 2024