Structural Biology News and Research

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Birth of an enzyme

Mankind triumphed in a recent 'competition' against nature when scientists succeeded in creating a new type of enzyme for a reaction for which no naturally occurring enzyme has evolved.

25 Mar 2008

Malaysia Genome Institute advances bioinformatics research using SGI Technology

To create an optimal workflow that encompasses the diverse computing requirements of bioinformatics research, the Malaysia Genomics Institute (MGI) selected SGI to design a unique SGI hybrid computing solution.

21 Feb 2008

New key finding in neurodevelopment

A longstanding puzzle in neurodevelopment may have yielded up a key secret. A team led by scientists at Weill Cornell Medical College says they have determined how events at the very tips of the developing neuron's long, skinny axon affect gene transcription back in the cell's distant nucleus.

20 Feb 2008

New nanomedicine research for prostate cancer

The Prostate Cancer Foundation, largely through the generosity of David H. Koch, has given $5 million to four institutions, including Weill Cornell Medical College, to support novel research in prostate cancer. The gift is one of the largest-ever individual donations for prostate cancer research.

29 Jan 2008

New target found for asthma

An enzyme released by mast cells in the lungs appears to play a key role in the tightening of airways that is a hallmark of asthma -- pointing to a potential new target for treatment against the illness.

29 Jan 2008

New clue found to the cause of Parkinson's disease

A glitch in the mechanism by which cells recycle damaged components may trigger Parkinson's disease, according to a study by scientists at the Albert Einstein College of Medicine of Yeshiva University.

3 Jan 2008

First view of synapse in real time

For the first time, scientists at Weill Cornell Medical College in New York City have observed in real time a cellular mechanism that's crucial to how brain cells communicate.

14 Dec 2007

Researchers capture key step in process that allows materials to move in and out of cells

A group of Purdue University researchers has captured a key step in the metabolic process that allows materials, such as nutrients and drug treatments, to move in and out of cells.

3 Dec 2007

Dyslexia expert Dr. Bruce McCandliss awarded Presidential honor

Dr. Bruce McCandliss, a psychologist at the Sackler Institute for Developmental Psychobiology and associate professor of psychology in psychiatry at Weill Cornell Medical College, has received a commendation by the President of the United States in the form of a Presidential Early Career Award for Scientists and Engineers (PECASE).

20 Nov 2007

Stanford researchers get precise picture of cell target for drugs

More than half of all drugs given to patients work by targeting a particular type of "docking station," or receptor, found on body cells, to steer the cell's machinery toward healing an illness.

25 Oct 2007

First high-res 3D structures of first mammalian GRP94 protein solved

Dr. Dan Gewirth, Hauptman-Woodward senior research scientist, has just solved the structure of the first mammalian GRP94 protein implicated in immune diseases such as sepsis, AIDS and certain cancers.

15 Oct 2007

RecA family recombinases repair DNA damages

A biochemistry research team led by Dr. Andrew H.-J. Wang and Dr. Ting-Fang Wang at the Institute of Biological Chemistry, Academia Sinica(IBCAS), has discovered that the RecA family recombinases function as a new type of rotary motor proteins to repair DNA damages.

13 Sep 2007

Link between nicotine and atherosclerosis

It's well known that smoking cigarettes increases risk for a host of serious health problems from cancer to heart disease. Now a new study from Weill Cornell Medical College in New York City looks at how they do their dirty work by contributing to atherosclerosis, or hardening of the arteries. The evidence points to nicotine, the addictive chemical in cigarettes.

11 Sep 2007

University of Utah receives $19.2 Million for HIV research

University of Utah biochemist Wesley I. Sundquist, Ph.D., has been awarded a five-year, $19.2 million National Institutes of Health (NIH) grant to establish an HIV research center to study the structural biology of the AIDS-causing virus.

3 Sep 2007

Scientists discover the dynamics of transcription in living mammalian cells

Transcription the transfer of DNA's genetic information through the synthesis of complementary molecules of messenger RNA forms the basis of all cellular activities.

7 Aug 2007

Nicotine rush hinges on sugar in neurons

As with other questions involving good sensations, the answer appears to be sugar.

23 Jul 2007

Lubert Stryer wins National Medal of Science

Neurobiologist Lubert Stryer, MD, of the Stanford University School of Medicine, will receive the nation's highest scientific honor, the National Medal of Science, for his achievements in a wide range of fields that included the development of a DNA chip used in genetics.

19 Jul 2007

Discovery of enzyme critical in DNA replication

In this week's issue of Science, researchers from the National Institute of Environmental Health Sciences (NIEHS) and Umea University in Sweden report an important discovery about a critical new role that an enzyme called DNA polymerase epsilon plays in replicating DNA in higher organisms such as yeast and perhaps even humans.

9 Jul 2007

Investigating life in extreme environments

From the deepest seafloor to the highest mountain, from the hottest region to the cold Antarctic plateau, environments labelled as extreme are numerous on Earth and they present a wide variety of features and characteristics.

5 Jul 2007

Scientists create sheets of protein-gold arrays

In groundbreaking research, scientists have demonstrated the ability to strategically attach gold nanoparticles -- particles on the order of billionths of a meter -- to proteins so as to form sheets of protein-gold arrays.

28 Jun 2007