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UAB researchers show beneficial effect of verapamil for patients with Type 1 diabetes

In 2012, University of Alabama at Birmingham researcher Anath Shalev, M.D., reported that a decades-old blood pressure medication called verapamil completely reversed diabetes in animal models.

25 Aug 2023

Researchers discover new therapeutic approach for neuroblastoma

Neuroblastomas are tumors of the nervous system. They can form in many places in the body and are the most common cause of cancer-related deaths in young children.

25 Aug 2023

New 3D model mimics brain cell and immune cell interactions in Alzheimer's disease

Cognitive decline associated with Alzheimer's disease (AD) develops when neurons begin to die, which can be caused by inappropriate immune responses and excessive inflammation in the brain triggered by amyloid beta deposits and tau tangles, two hallmarks of the disease.

25 Aug 2023

Study shows not all adrenal carcinoma patients need mitotane after surgery

After the complete tumor resection, not all patients with an adrenocortical carcinoma require the previous standard therapy Mitotane. Professors Martin Fassnacht and Massimo Terzolo show this in a clinical trial.

25 Aug 2023

Researchers discover how proteins regulate 'treadmilling' in cells

Researchers at the Centre for Genomic Regulation (CRG) have discovered how proteins work in tandem to regulate 'treadmilling', a mechanism used by the network of microtubules inside cells to ensure proper cell division.

25 Aug 2023

Two small molecule inhibitors can help improve precision, efficiency of CRISPR-Cas9 gene editing

A new study published in Nature Communications demonstrates how small molecule inhibitors can be used to improve the precision and efficiency of CRISPR-Cas9 gene editing.

25 Aug 2023

Researchers develop new, modular strategy for T-cell-based immunotherapy

Immunotherapies for cancer aim to induce the immune system to combat cancer cells more effectively.

25 Aug 2023

Midnolin protein plays key role in breaking down short-lived nuclear proteins

Short-lived proteins control gene expression in cells to carry out a number of vital tasks, from helping the brain form connections to helping the body mount an immune defense.

24 Aug 2023

Cholesterol loss in inner ear linked to age-related hearing loss

Researchers led by María Eugenia Gomez-Casati, the Institute of Pharmacology, School of Medicine, University of Buenos Aires-CONICET; Mauricio Martin, the Institute of Medical Research Mercedes; and Martín Ferreyra, (INIMEC-CONICET-UNC), National University of Córdoba in Argentina report that age-related hearing loss is associated with a decrease of cholesterol in the inner ear.

24 Aug 2023

New research sheds light on role of KRAS mutations in pancreatic cancer

Researchers at The University of Texas MD Anderson Cancer Center have uncovered a functional role for KRAS mutations in pancreatic cancer and rapidly translated these findings into a novel therapeutic approach combining a KRAS G12D inhibitor with immune checkpoint inhibitors for early- and late-stage KRAS G12D-mutant pancreatic cancer.

24 Aug 2023

SCALE-UP Counts program shows text messaging can be an effective tool for public health

An examination of the SCALE-UP Counts program was recently published in the journal Pediatrics.

24 Aug 2023

Stem cell patch for treating macular degeneration to enter phase 2b clinical trial

A stem cell patch developed by USC researchers for patients with macular degeneration will soon be tested in a phase 2b clinical trial.

24 Aug 2023

Genetics and environment influence immune responses to SARS-CoV-2

During the COVID-19 pandemic, the clinical spectrum observed among people infected with SARS-CoV-2 ranged from asymptomatic carriage to death.

24 Aug 2023

Scientists create new test to identify people at risk of developing myeloid leukemias

Scientists have created a new test for identifying people at risk of developing acute myeloid leukaemia and related cancers, years before they do.

24 Aug 2023

Age-related changes in the blood system can exacerbate colon cancer

Researchers at the University of Florida College of Medicine have discovered how common age-related changes in the blood system can make certain colon cancers grow faster.

24 Aug 2023

KAUST researchers refute challenges to targeted cancer therapy

Drugs that inhibit a key protein should offer new targeted cancer therapy for leukemia and breast cancer.

24 Aug 2023

Lung cells can be trained to counteract inflammation

Inflammation is a standard part of our bodies' immune system response. But sometimes this response becomes hyperactivated in our lungs, causing inflammation to continue unchecked, which can be fatal. Many deaths from COVID-19 have been due to excessive inflammation, which results in acute lung injury.

24 Aug 2023

B Cell News and Research

UAB researchers show beneficial effect of verapamil for patients with Type 1 diabetes

Researchers discover new therapeutic approach for neuroblastoma

New 3D model mimics brain cell and immune cell interactions in Alzheimer's disease

Study shows not all adrenal carcinoma patients need mitotane after surgery

Researchers discover how proteins regulate 'treadmilling' in cells

Two small molecule inhibitors can help improve precision, efficiency of CRISPR-Cas9 gene editing

Researchers develop new, modular strategy for T-cell-based immunotherapy

Midnolin protein plays key role in breaking down short-lived nuclear proteins

Cholesterol loss in inner ear linked to age-related hearing loss

New research sheds light on role of KRAS mutations in pancreatic cancer

SCALE-UP Counts program shows text messaging can be an effective tool for public health

Stem cell patch for treating macular degeneration to enter phase 2b clinical trial

Genetics and environment influence immune responses to SARS-CoV-2

Scientists create new test to identify people at risk of developing myeloid leukemias

Age-related changes in the blood system can exacerbate colon cancer

KAUST researchers refute challenges to targeted cancer therapy

Lung cells can be trained to counteract inflammation

Researchers find link between topography of the genome and presence of cancer mutations

The role played by the gut microbiome in metabolizing selected sweeteners

Small molecule inhibitor of the NLRP3 inflammasome for treating autoinflammatory diseases

Using single B cell screening to boost antibody discovery eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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