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One-third of patients with heart pumps develop infection at abdominal power connection site

Cardiac surgeons and cardiologists at the University of Maryland Heart Center are part of a multi-center clinical trial evaluating the efficacy of powering heart pumps through a skull-based connector behind the ear. Typically, these devices for patients with severe heart failure are energized through an electrical cord connected at an abdominal site, where potentially deadly infections can develop.

8 Aug 2013

Janssen receives EC approval to use VELCADE as induction therapy in patients with multiple myeloma

Janssen-Cilag International NV announced today that the European Commission has approved the use of VELCADE (bortezomib) as induction therapy (a first therapeutic option) in combination with dexamethasone or thalidomide and dexamethasone. This licence extension will apply to adult patients with previously-untreated multiple myeloma who are eligible for high-dose chemotherapy with haematological stem cell transplantation.

8 Aug 2013

Scientist receives grant to commercialize technology developed for repairing skin injuries

The Chemical Alliance Zone's Chemicals and Materials Commercialization Fund has awarded $20,000 to a Marshall University scientist to help bring to market a technology he has developed for repairing skin injuries.

8 Aug 2013

Researchers identify mechanism responsible for loss of tumor-suppressor gene in soft-tissue sarcomas

Researchers have discovered a novel mechanism responsible for the loss of a critical tumor-suppressor gene in rhabdomyosarcoma and other soft-tissue sarcomas, rare cancers that strike mainly children and often respond poorly to treatment. Their cause is largely unknown.

8 Aug 2013

Researchers develop nanoprobe technique to help treat fatal diseases more effectively

Researchers at the University of Southampton, in collaboration with colleagues at the University of Cambridge, have developed a technique to help treat fatal diseases more effectively.

8 Aug 2013

Autologous tumor cell vaccination: An effective strategy to advance long-term leukemia control

Patients with advanced chronic lymphocytic leukemia often receive donor transplants that effectively "reboot" their own immune defenses, which then attack and potentially cure the hard-to-treat disease. However, there is a high rate of relapse in these patients, and the transplanted immune cells may also harm normal tissues, causing graft-versus-host disease.

7 Aug 2013

Study observes that long-term use of antihypertensive drugs associated with breast cancer risk

Older women who take certain types of medication to combat high blood pressure may be putting themselves at greater risk for developing breast cancer, according to a new study by a team of Fred Hutchinson Cancer Research Center scientists led by Christopher Li, M.D., Ph.D.

6 Aug 2013

Tumor cell vaccination has potential to enhance anti-tumor responses following allo-HSCT

Chronic lymphocytic leukemia (CLL) is a cancer of the blood and bone marrow that most often affects older adults. CLL responds to bone marrow stem cell transplantation (allo-HSCT); however, the rate of relapse for CLL remains relatively high.

6 Aug 2013

Celiac disease patients with persistent intestine damage are at higher risk of lymphoma

Patients with celiac disease who had persistent intestine damage (identified with repeat biopsy) had a higher risk of lymphoma than patients whose intestines healed, according to findings published in the August 6, 2013, issue of Annals of Internal Medicine.

6 Aug 2013

Quick zaps of ultraviolet light can boost vitamin D levels in mushrooms

Quick zaps of ultraviolet light can boost the vitamin D levels in mushrooms in seconds, turning the fungi into an even healthier food, according to Penn State food scientists.

5 Aug 2013

BioLineRx reports positive results from pre-clinical trials with RHB-104 for treatment of thrombocytopenia

BioLineRx, a biopharmaceutical development company, announced today that BL-8040 has been shown in pre-clinical trials to be effective for the treatment of thrombocytopenia, or reduced platelet production.

5 Aug 2013

Researchers identify precise method for determining bone marrow involvement in DLBCL patients

A more precise method for determining bone marrow involvement in patients with diffuse large B-cell lymphoma-a key factor in tailoring patient management plans-has been identified by researchers in a study published in the August issue of The Journal of Nuclear Medicine.

2 Aug 2013

Duke Medicine researchers identify a protein critical to TMJD pain

Temporomandibular joint disorder (TMJD) is the most common form of oral or facial pain, affecting over 10 million Americans. The chronic disorder can cause severe pain often associated with chewing or biting down, and lacks effective treatments.

2 Aug 2013

Study offers new hope for treatment of diffuse large B-cell lymphoma

Researchers have discovered how an experimental drug is capable of completely eradicating human lymphoma in mice after just five doses. The study, led by researchers at Weill Cornell Medical College, sets the stage for testing the drug in clinical trials of diffuse large B-cell lymphoma, the most common subtype of non-Hodgkin lymphoma, itself the seventh most frequently diagnosed cancer in the U.S.

2 Aug 2013

International meeting to focus on carbon ion radiotherapy for cancer patients

Cancer experts from around the world are converging in Denver on Thursday and Friday to analyze the success of cutting-edge radiation therapies, and to determine how one promising treatment option could be delivered for the first time to cancer patients in the United States.

2 Aug 2013

Researchers reveal location of human blood stem cells that may improve bone marrow transplants

McMaster University researchers have revealed the location of human blood stem cells that may improve bone marrow transplants. The best stem cells are at the ends of the bone.

2 Aug 2013

Microbiologists identify staph-killing compound that may be effective for osteomyelitis

Osteomyelitis, a debilitating bone infection most frequently caused by Staphylococcus aureus ("staph") bacteria, is particularly challenging to treat.

2 Aug 2013

Cambridge scientists identify molecular 'on/off' switch in malignant germ cell tumours

Cambridge scientists have identified an 'on/off' switch in a type of cancer which typically occurs in the testes and ovaries called 'malignant germ cell tumours'. The research was published today, 01 August, in the journal Cancer Research.

1 Aug 2013

Finding could influence effectiveness of bone marrow transplants for late-stage leukemia

Eight years ago, two former Stanford University postdoctoral fellows, one of them still in California and the other at the Harvard Stem Cell Institute in Cambridge, began exchanging theories about why patients with leukemia stop producing healthy blood cells. What was it, they asked, that caused bone marrow to stop producing normal blood-producing cells?

1 Aug 2013

Reinnervate's Alvetex Scaffold system chosen for 3D osteocytic cell culture experiments in microgravity

Market leading 3D cell culture company Reinnervate Ltd today announced that its Alvetex®Scaffold system has been chosen by a group at Massachusetts General Hospital for the first ever 3D osteocytic cell culture experiments in microgravity.

31 Jul 2013

Bone News and Research

One-third of patients with heart pumps develop infection at abdominal power connection site

Janssen receives EC approval to use VELCADE as induction therapy in patients with multiple myeloma

Scientist receives grant to commercialize technology developed for repairing skin injuries

Researchers identify mechanism responsible for loss of tumor-suppressor gene in soft-tissue sarcomas

Researchers develop nanoprobe technique to help treat fatal diseases more effectively

Autologous tumor cell vaccination: An effective strategy to advance long-term leukemia control

Study observes that long-term use of antihypertensive drugs associated with breast cancer risk

Tumor cell vaccination has potential to enhance anti-tumor responses following allo-HSCT

Celiac disease patients with persistent intestine damage are at higher risk of lymphoma

Quick zaps of ultraviolet light can boost vitamin D levels in mushrooms

BioLineRx reports positive results from pre-clinical trials with RHB-104 for treatment of thrombocytopenia

Researchers identify precise method for determining bone marrow involvement in DLBCL patients

Duke Medicine researchers identify a protein critical to TMJD pain

Study offers new hope for treatment of diffuse large B-cell lymphoma

International meeting to focus on carbon ion radiotherapy for cancer patients

Researchers reveal location of human blood stem cells that may improve bone marrow transplants

Microbiologists identify staph-killing compound that may be effective for osteomyelitis

Cambridge scientists identify molecular 'on/off' switch in malignant germ cell tumours

Finding could influence effectiveness of bone marrow transplants for late-stage leukemia

Reinnervate's Alvetex Scaffold system chosen for 3D osteocytic cell culture experiments in microgravity

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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