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Bringing highly potent cell therapy products to market

There are two main challenges and both relate to manufacturing. The first one is to make sure you can manufacture therapies with reasonable costs and the second one is to make sure that you can balance the capacity you need with the demands.

31 Jul 2017

Research scientist at Kessler Foundation receives $231,000 grant from American Heart Association

Olga Boukrina, PhD, research scientist in Stroke Rehabilitation Research at Kessler Foundation, has received a three-year award from the American Heart Association(AHA) valued at $231,000.

29 Jul 2017

Structure of protein in salmon virus could inform strategies to treat flu in humans

The structure of a protein key to the survival and spread of a virus that affects salmon could inform strategies to treat the flu in humans, according to scientists at Rice University.

28 Jul 2017

When high deductibles hurt: Even insured patients postpone care

In November 2015, Tina Heck was in her garage lifting 40-pound bags of wood pellets to fuel her heating stove, when something went very wrong with her back.

28 Jul 2017

Scientists uncover link between backup pathogen-fighting system and mutations in Crohn's patients

Genes that regulate a cellular recycling system called autophagy are commonly mutated in Crohn's disease patients, though the link between biological housekeeping and inflammatory bowel disease remained a mystery. Now, researchers at UT Southwestern Medical Center have uncovered an intriguing clue.

28 Jul 2017

Combining intraoperative imaging with PET scans helps surgeons remove hidden cancer cells

Surgeons were able to identify and remove a greater number of cancerous nodules from lung cancer patients when combining intraoperative molecular imaging (IMI) – through the use of a contrast agent that makes tumor cells glow during surgery – with preoperative positron emission tomography (PET) scans.

27 Jul 2017

New report says completing a course of antibiotics even after symptoms abate is overrated

Antibiotics are a boon to mankind and as more and more microorganisms are developing a resistance to these drugs, researchers are delving deeper into the mechanisms of this resistance. It is a commonly held view that once begun, a course of antibiotics should be completed to prevent the emergence of resistance among the microbes.

26 Jul 2017

Study explores long-term consequences of breast surgery on woman's sensuality, sexual function

Does the type of surgery used to treat breast cancer impact a woman's sensuality and sexual function in survivorship? New research from Women & Infants Hospital analyzed the association of surgical modality with sexual function and found that breast-specific sensuality and appearance satisfaction are better with lumpectomy and may correlate with improved sexual function post-operatively.

26 Jul 2017

Genetic test to predict IBD severity in children

Inflammatory bowel disease (IBD) is a chronic relapsing inflammation of the gastrointestinal tract with abdominal pain and diarrhea being the most common symptoms. It can be challenging to diagnose as gastrointestinal complaints mimicking IBD are common.

26 Jul 2017

Penn Medicine professor receives Outstanding Early Career Investigator Award from AHA

Benjamin L. Prosser, PhD, an assistant professor of Physiology, in the Perelman School of Medicine at the University of Pennsylvania, has received the Outstanding Early Career Investigator Award from the American Heart Association's Council on Basic Cardiovascular Sciences, one of its scientific divisions.

25 Jul 2017

MRI techniques can help spot, track cognitive impairment in professional fighters

Images of the brain's gray and white matter obtained with multiple MRI techniques can help identify and track cognitive impairment in active professional fighters, according to a new study published online in the journal Radiology.

25 Jul 2017

Researchers present novel gene-editing technique to prevent retinal angiogenesis

A research team from the Schepens Eye Research Institute of Massachusetts Eye and Ear has successfully prevented mice from developing angiogenesis of the retina--the sensory tissue at the back of the eye--using gene-editing techniques with CRISPR-Cas9.

25 Jul 2017

Scientists gain better understanding of genetics behind lean body mass

Scientists from the Institute for Aging Research at Hebrew SeniorLife, along with several other research institutions are making great strides in understanding the genetics behind lean body mass, which is largely made up of muscle mass.

24 Jul 2017

Wistar scientists discover new therapeutic strategy for difficult-to-treat form of ovarian cancer

A potential new therapeutic strategy for a difficult-to-treat form of ovarian cancer has been discovered by Wistar scientists. The findings were published online in Nature Cell Biology.

24 Jul 2017

Antiperspirants can be safely used during breast radiotherapy, study suggests

Women undergoing daily radiation therapy for breast cancer are commonly told they should not use antiperspirant for fear that it could cause greater radiation damage to the skin, but a new study from the Perelman School of Medicine at the University of Pennsylvania shows that advice is not based on sound science.

24 Jul 2017

High dose flu vaccine reduces risk of respiratory and all-cause hospitalizations, study finds

In the largest nursing home study to date on the effect of a high dose (HD) flu vaccine, researchers found that vaccines with four times the antigen of standard flu (SD) vaccines significantly reduced the risk of respiratory and all-cause hospitalization during flu season.

21 Jul 2017

People with genetic susceptibility to Alzheimer's may have greater cognitive deficits with sleep-disordered breathing

People who carry a genetic susceptibility to Alzheimer's disease appear to be at greater risk of diminished cognition from sleep-disordered breathing than those without the susceptibility, according to new research published online, ahead of print in the Annals of the American Thoracic Society.

21 Jul 2017

Simple financial incentive may improve rate of colonoscopy screenings

Offering $100 to patients eligible for a preventive colonoscopy screening more than doubled the rate of screening when compared to a simple emailed request, according to new research from the Perelman School of Medicine at the University of Pennsylvania.

21 Jul 2017

Study finds no convincing evidence to support link between PPI use and dementia risk

Several studies have reported associations between proton-pump inhibitor (PPI) use and dementia. New research published on July 18 in Gastroenterology, the official journal of the American Gastroenterological Association, puts these claims to rest.

20 Jul 2017

Scientists create new probe for imaging proteins involved in fibrogenesis

Organs respond to injuries with the formation of new fibrous tissue, which can result in scarring. This process called fibrogenesis can now be monitored noninvasively on a molecular level, as American scientists report in the journal Angewandte Chemie.

19 Jul 2017

Medical School News and Research

Bringing highly potent cell therapy products to market

Research scientist at Kessler Foundation receives $231,000 grant from American Heart Association

Structure of protein in salmon virus could inform strategies to treat flu in humans

When high deductibles hurt: Even insured patients postpone care

Scientists uncover link between backup pathogen-fighting system and mutations in Crohn's patients

Combining intraoperative imaging with PET scans helps surgeons remove hidden cancer cells

New report says completing a course of antibiotics even after symptoms abate is overrated

Study explores long-term consequences of breast surgery on woman's sensuality, sexual function

Genetic test to predict IBD severity in children

Penn Medicine professor receives Outstanding Early Career Investigator Award from AHA

MRI techniques can help spot, track cognitive impairment in professional fighters

Researchers present novel gene-editing technique to prevent retinal angiogenesis

Scientists gain better understanding of genetics behind lean body mass

Wistar scientists discover new therapeutic strategy for difficult-to-treat form of ovarian cancer

Antiperspirants can be safely used during breast radiotherapy, study suggests

High dose flu vaccine reduces risk of respiratory and all-cause hospitalizations, study finds

People with genetic susceptibility to Alzheimer's may have greater cognitive deficits with sleep-disordered breathing

Simple financial incentive may improve rate of colonoscopy screenings

Study finds no convincing evidence to support link between PPI use and dementia risk

Scientists create new probe for imaging proteins involved in fibrogenesis

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

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