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Challenges associated with prescribing exercise to diabetic patients taking metformin

In a recent study published in the Sports Medicine and Health Science journal, researchers assessed the impact of exercise precision medicine on type 2 diabetes.

21 Feb 2023

A growing burden of alcoholic hepatitis

A recent study published in the journal Medical Clinics of North America discussed the diagnosis, treatment, and pathophysiology of alcoholic hepatitis (AH).

21 Feb 2023

Study investigates anti-VEGF treatment for inflammatory eye disease in HTLV-1–infected ocular cells

A retrovirus known as human T-cell lymphotropic virus type 1 (HTLV-1) is known to cause a number of diseases, including inflammatory diseases of the eye. Recently, researchers in Japan have investigated an antibody treatment for inflammatory eye disease in ocular cells infected with HTLV-1.

21 Feb 2023

Whole genome sequencin provides clearest picture of the genetic changes leading to Hodgkin lymphoma

To create the most effective, personalized treatment plans for patients with Hodgkin lymphoma or other cancers, scientists and clinicians need the clearest picture of the genetic changes leading to the cancer's development.

21 Feb 2023

Long-acting antiretroviral treatment may improve outcomes in underserved HIV patients

A long-acting antiretroviral treatment (LA-ART) given every four to eight weeks, and delivered with comprehensive support services, suppressed HIV in people who were previously not virologically suppressed.

21 Feb 2023

Income level impacts tumor recurrence and survival in women with ER-positive breast cancer

Patients with early-stage estrogen receptor-positive breast cancer who live in low-income neighborhoods are likelier to have more-aggressive tumors and significantly lower overall survival (OS) than those in higher-income neighborhoods, according to research led by Roswell Park Comprehensive Cancer Center.

21 Feb 2023

Life Sciences Innovator Category Winner 2023

Following a rigorous application process, we are proud to announce that Seda have been selected as the UK Life Sciences Innovator Winner 2023 in the Application, Product & Service Design Category.

From Seda Pharmaceutical Development Services 21 Feb 2023

Researchers provide a framework for unifying and categorizing neurodegenerative diseases based on eight hallmarks

Researchers presented eight hallmarks of neurodegenerative diseases (NDDs), their in vivo biomarkers, and interactions to help categorize NDDs and specify patients within a specific NDD.

21 Feb 2023

Ethnic and regional minorities derive at least as much cardiovascular benefit from lipid-lowering therapies

Minority ethnicities and regions derive at least as much cardiovascular benefit from lipid-lowering therapies as majority groups despite being underrepresented in clinical trials, according to a study published today in the European Journal of Preventive Cardiology, a journal of the ESC.

21 Feb 2023

Adipose-targeted delivery of thyroid hormone alleviates hypercholesterolemia and atherosclerosis

A research team from LKS Faculty of Medicine, the University of Hong Kong (HKUMed) has developed thyroid hormone (TH) - encapsulated nanoparticles modified with adipose-homing peptide, which selectively transport TH to adipose tissues.

20 Feb 2023

Brexanolone inhibits key systemic inflammatory pathways associated with post-partum depression

Post-partum depression (PPD) develops after childbirth and affects both the mother's and the infant's health by preventing healthy bonding.

20 Feb 2023

Spinal cord stimulation technology instantly improves arm and hand mobility in stroke patients

A neurotechnology that stimulates the spinal cord instantly improves arm and hand mobility, enabling people affected by moderate to severe stroke to conduct their normal daily activities more easily, report researchers from the University of Pittsburgh and Carnegie Mellon University today in Nature Medicine.

20 Feb 2023

Study indicates that macrophages that reside in the lymph nodes contribute to the initial Zika virus spread

Researchers mapped Zika virus infections in the lymph nodes to determine how the Zika virus enters from different points in the skin and disseminates through the body.

20 Feb 2023

Utilizing CRISPR to discover new therapy options for COPD

In this interview, we speak to Ceri Wiggins, a Director at AstraZeneca, about the many applications of CRISPR and its role in discovering new COPD therapies.

From Society for Laboratory Automation and Screening (SLAS) 20 Feb 2023

In-depth assessment of muscle biopsies in patients with long COVID

Researchers analyzed skeletal muscle biopsies of patients with persistent fatigue and malaise post-exertion to determine the underlying mechanisms of long COVID.

20 Feb 2023

Are SGLT2 inhibitors the next blockbuster drug?

Recent clinical trials investigating the therapeutic potency of sodium-glucose cotransporter 2 inhibitors (SGLT2i) have highlighted that this drug is highly effective in treating patients with cardiovascular and renal diseases.

19 Feb 2023

Gut dysbiosis and sepsis susceptibility among pregnant women

Researchers describe the role of gut dysbiosis during pregnancy in promoting excessive macrophage pyroptosis, which increases vulnerability to sepsis.

19 Feb 2023

UTHSC researchers secure $308,000 grant from Department of Defense for dementia study

Repeated traumatic brain injuries (TBI) in soldiers and military personnel can cause behavioral, neurological, and cognitive effects and lead to dementia.

19 Feb 2023

Proposal to scrap England’s long term plan for cancer could cost lives, experts warn

The UK government's proposal to roll England's long term plan for cancer into one strategy covering all major conditions, such as cardiovascular disease, chronic respiratory disease, dementia, mental health conditions, and musculoskeletal disorders is "a catastrophic decision that will cost lives," warn experts in The BMJ today.

17 Feb 2023

Ferroptosis could be the key to making effective immunotherapies against liver cancer

Iron-dependent cell death (ferroptosis) is a type of programmed cell death by means of which the body kills off diseased, defective or superfluous cells.

17 Feb 2023

Therapy News and Research

Challenges associated with prescribing exercise to diabetic patients taking metformin

A growing burden of alcoholic hepatitis

Study investigates anti-VEGF treatment for inflammatory eye disease in HTLV-1–infected ocular cells

Whole genome sequencin provides clearest picture of the genetic changes leading to Hodgkin lymphoma

Long-acting antiretroviral treatment may improve outcomes in underserved HIV patients

Income level impacts tumor recurrence and survival in women with ER-positive breast cancer

Life Sciences Innovator Category Winner 2023

Researchers provide a framework for unifying and categorizing neurodegenerative diseases based on eight hallmarks

Ethnic and regional minorities derive at least as much cardiovascular benefit from lipid-lowering therapies

Adipose-targeted delivery of thyroid hormone alleviates hypercholesterolemia and atherosclerosis

Brexanolone inhibits key systemic inflammatory pathways associated with post-partum depression

Spinal cord stimulation technology instantly improves arm and hand mobility in stroke patients

Study indicates that macrophages that reside in the lymph nodes contribute to the initial Zika virus spread

Utilizing CRISPR to discover new therapy options for COPD

In-depth assessment of muscle biopsies in patients with long COVID

Are SGLT2 inhibitors the next blockbuster drug?

Gut dysbiosis and sepsis susceptibility among pregnant women

UTHSC researchers secure $308,000 grant from Department of Defense for dementia study

Proposal to scrap England’s long term plan for cancer could cost lives, experts warn

Ferroptosis could be the key to making effective immunotherapies against liver cancer

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