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Researchers reveal promising biomarker for vascular disease relapse

Researchers at Okayama University report in the journal Arthritis & Rheumatology that monitoring a particular antigen can be used for predicting relapse of the vascular disease AAV.

28 Feb 2019

Researchers are developing and testing novel gene therapy to cure Crigler-Najjar syndrome

Crigler-Najjar syndrome affects about one in a million people at birth. Because of a defective gene, these individuals lack an essential enzyme in their liver to eliminate bilirubin, a toxic bile pigment that accumulates in all body tissues causing jaundice and potentially leading to irreversible and lethal neurological damage.

28 Feb 2019

Custom-designed proteins may help generate antibodies to inhibit HIV infection

A new way to create proteins that can sneak through HIV's protective coating may be a step toward understanding the key components needed for developing a vaccine for the virus, according to researchers.

27 Feb 2019

Porvair Sciences to improve the diagnosis and treatment of ovarian cancer

Porvair Sciences reports on its involvement in a new £2.6 million project led by Swansea University (UK) that aims to dramatically improve the diagnosis and treatment of ovarian cancer.

From Chromatrap® - Porvair Sciences Ltd 27 Feb 2019

Base Pair Biotechnologies to develop point-of-care tests for opioids in newborns

Base Pair Biotechnologies announced today the receipt of a Fast Track Small Business Innovation Research grant from the National Institute on Drug Abuse of the NIH

From Base Pair Biotechnologies, Inc. 25 Feb 2019

Risk of tick bite potentially leading to red meat allergy is higher than expected

Until now it has been believed that in order for a tick to trigger an allergic immune response to alpha-gal in humans, the tick would need to have recently fed on the alpha-gal-rich blood of a mammal.

25 Feb 2019

Researchers engineer 'antibody-like' T cell receptors to combat deadly virus

Researchers have engineered "antibody-like" T cell receptors that can specifically stick to cells infected with cytomegalovirus, or CMV, a virus that causes lifelong infection in more than half of all adults by age 40.

23 Feb 2019

New identified biomarker predicts patients who might benefit from HER2-targeted agents

In an effort to further individualize therapy and avoid over-treating patients, researchers at the Johns Hopkins Kimmel Cancer Center report a new study using PET scans has identified a biomarker that may accurately predict which patients with one type of HER2-positive breast cancer might best benefit from standalone HER2-targeted agents, without the need for standard chemotherapy.

22 Feb 2019

Behavior change of prolonged smoking cessation may delay or prevent onset of seropositive rheumatoid arthritis

In an Arthritis Care & Research analysis of 230,732 women, those who quit smoking many years ago had a lower risk of a certain form of rheumatoid arthritis (RA) compared with women who recently quit.

21 Feb 2019

Sustained smoking cessation can lower risk of seropositive RA

Smoking is an important risk factor for developing the most common form of rheumatoid arthritis and other inflammatory diseases, but a critical question remains: Can those who quit smoking delay or prevent RA or have they permanently and irrevocably altered their risk of the disease? A new study by investigators from Brigham and Women's Hospital leverages data from the Nurses' Health Studies to find out.

21 Feb 2019

Reduced antibody adaptability may make the elderly more vulnerable to influenza

The influenza vaccine may be less effective in the elderly because their B cells are less capable of producing antibodies that can adapt to protect against new viral strains, researchers report February 19 in the journal Cell Host & Microbe.

21 Feb 2019

Researchers discover a new promising target to improve HIV vaccines

In the quest to develop an effective HIV vaccine, researchers have focused attention on identifying and targeting the region of the virus's outer envelope where a lineage of antibodies are able to dock and neutralize the virus.

21 Feb 2019

Why melanoma tumors in the brain may be worse?

Melanoma tumors that have spread to the brain are equipped to thwart immunotherapies and targeted therapies that succeed against tumors growing in other sites.

20 Feb 2019

New technique could expedite cancer diagnosis, lead to better patient outcomes

The days - or even weeks - spent waiting for the results of a cancer-screening test can feel like an eternity. Especially when early diagnosis and quick action are tied to better outcomes.

20 Feb 2019

New screening method could catch organ rejection much earlier without a biopsy needle

Too often, it's only after a transplanted organ has sustained serious damage that a biopsy reveals the organ is in rejection. A new screening method using sensor particles and a urine test could catch rejection much earlier, more comprehensively, and without a biopsy needle.

20 Feb 2019

Intervention can increase exclusive breastfeeding rates

Interventions which educate and support new mothers in West Africa to exclusively breastfeed (where infants are only fed breast milk) can significantly increase the practice, according to new research published in The Lancet Global Health.

15 Feb 2019

Conformance of genetic characteristics found to be crucial for longer preservation of kidney graft

The conformance of genetic characteristics is essential for the long-term function after kidney transplantation. This is the central result of a recent study in the top journal “The Lancet” with more than 500 patients after kidney transplantation, conducted by a global consortium led by Rainer Oberbauer and his colleagues Roman Reindl-Schwaighofer and Andreas Heinzel from the Division of Nephrology and Dialysis at MedUni Vienna.

15 Feb 2019

Celiac disease may be caused by gastrointestinal infection in childhood

A new study has found that a childhood stomach bug may be the cause of celiac disease later in life. The findings could pave the way for a vaccine to protect against the disease.

15 Feb 2019

Immune checkpoint molecule protects against future development of cancer

A research team at the University of Louisville has discovered that an immune checkpoint molecule they developed for cancer immunotherapy, also protects against future development of multiple types of cancer when administered by itself.

15 Feb 2019

Mount Sinai awarded $12.5 million NIH grant for research program in aging biology

Researchers from the Icahn School of Medicine at Mount Sinai have been awarded a $12.5 million grant from the National Institute on Aging, part of the National Institutes of Health, for a five-year program called the U19 that consists of four multidisciplinary projects in aging biology.

14 Feb 2019

Antibodies News and Research

Researchers reveal promising biomarker for vascular disease relapse

Researchers are developing and testing novel gene therapy to cure Crigler-Najjar syndrome

Custom-designed proteins may help generate antibodies to inhibit HIV infection

Porvair Sciences to improve the diagnosis and treatment of ovarian cancer

Base Pair Biotechnologies to develop point-of-care tests for opioids in newborns

Risk of tick bite potentially leading to red meat allergy is higher than expected

Researchers engineer 'antibody-like' T cell receptors to combat deadly virus

New identified biomarker predicts patients who might benefit from HER2-targeted agents

Behavior change of prolonged smoking cessation may delay or prevent onset of seropositive rheumatoid arthritis

Sustained smoking cessation can lower risk of seropositive RA

Reduced antibody adaptability may make the elderly more vulnerable to influenza

Researchers discover a new promising target to improve HIV vaccines

Why melanoma tumors in the brain may be worse?

New technique could expedite cancer diagnosis, lead to better patient outcomes

New screening method could catch organ rejection much earlier without a biopsy needle

Intervention can increase exclusive breastfeeding rates

Conformance of genetic characteristics found to be crucial for longer preservation of kidney graft

Celiac disease may be caused by gastrointestinal infection in childhood

Immune checkpoint molecule protects against future development of cancer

Mount Sinai awarded $12.5 million NIH grant for research program in aging biology

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