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Zalicus commences first of two Z160 Phase 2a clinical studies for chronic neuropathic pain

Zalicus Inc., a biopharmaceutical company that discovers and develops novel treatments for patients suffering from pain and immuno-inflammatory diseases, today announced that it has initiated the first of two Phase 2a clinical studies with Z160, its first-in-class, oral, state-dependent, selective N-type calcium channel blocker for the treatment of chronic neuropathic pain indications.

5 Sep 2012

Avanir initiates enrollment in AVP-923 Phase II clinical trial for treatment of agitation in AD patients

Avanir Pharmaceuticals, Inc. today announced the enrollment of the first patient in study AVR-131. The study is a Phase II clinical trial investigating the use of AVP-923 for the treatment of agitation in patients with Alzheimer's disease.

5 Sep 2012

Closing large intracardiac shunts does not improve sleep apnea

Clinically significant shunting of blood through a patent foramen ovale is more common among patients with severe obstructive sleep apnea than in the general population, study findings indicate.

4 Sep 2012

Posterior medial cortex more specifically engaged in recall or imagination

You already know it's hard to balance your checkbook while simultaneously reflecting on your past. Now, investigators at the Stanford University School of Medicine - having done the equivalent of wire-tapping a hard-to-reach region of the brain - can tell us how this impasse arises.

4 Sep 2012

Eat your greens for healthy sperm genes

Men who consume a high amount of certain nutrients may produce healthier sperm than men who do not, an effect that appears to be more pronounced in older men, report US researchers.

3 Sep 2012

Herpes virus eventually impairs glucose regulation

The common herpes virus cytomegalovirus may be a risk factor for the development of Type 2 diabetes among elderly individuals, show study findings.

3 Sep 2012

Novel scoring system shows sclerotherapy improves pain of venous malformation

Ethanol sclerotherapy reduces the signs and symptoms of venous malformation in the majority of patients after approximately two sessions, report Japanese researchers who used a novel scoring system to evaluate treatment outcomes.

3 Sep 2012

Policymakers need to continue funding for adolescent smoking prevention programs: WSU

While many might see the case for programs to prevent adolescent cigarette smoking as already made, a pair of Wayne State University researchers believes that due to increasingly challenging economic times, policymakers need to be reminded to continue allocating funding for such programs.

3 Sep 2012

Link between sleep apnoea and overactive bladder syndrome in women

Sleep apnoea in women has been linked to overactive bladder syndrome in a new study. The research, presented at the European Respiratory Society's Annual Congress in Vienna, has provided new evidence suggesting a connection between the two conditions.

3 Sep 2012

Stanford engineers demonstrate feasibility of super-small, implantable cardiac device

A team of engineers at Stanford has demonstrated the feasibility of a super-small, implantable cardiac device that gets its power not from batteries, but from radio waves transmitted from outside the body. The implanted device is contained in a cube just eight-tenths of a millimeter in radius. It could fit on the head of pin.

1 Sep 2012

The safety of trainee surgeons: an interview with Prof Calvin Coffey

Surgical training begins at an undergraduate medical student level where students are involved in operations to a minor degree, and educated using a combination of didactic and problem-based approaches.

31 Aug 2012

Tunes and T-shirts for cardiac rehabilitation

Two studies presented at the European Society of Cardiology Congress in Munich, Germany, showed how researchers are developing innovative approaches to help patients get the most out of cardiac rehabilitation.

31 Aug 2012

FDA approves Ironwood’s LINZESS to treat irritable bowel syndrome with constipation

Ironwood Pharmaceuticals, Inc. and Forest Laboratories, Inc. announced today that LINZESS (linaclotide) was approved by the U.S. Food and Drug Administration (FDA) as a once-daily treatment for adult men and women suffering from irritable bowel syndrome with constipation (IBS-C) or chronic idiopathic constipation (CIC).

31 Aug 2012

Tunes and T-shirts for cardiac rehabilitation

29 Aug 2012

Deep-brain stimulation may stop uncontrollable shaking in patients with Parkinson's

Deep-brain stimulation (DBS) may stop uncontrollable shaking in patients with Parkinson's disease and essential tremor by imposing its own rhythm on the brain, according to two studies published recently by University of Alabama at Birmingham researchers in the journal Movement Disorders.

29 Aug 2012

NYU-Poly creates ultra-sensitive biosensor to identify small single virus particles

Researchers at Polytechnic Institute of New York University (NYU-Poly) have created an ultra-sensitive biosensor capable of identifying the smallest single virus particles in solution, an advance that may revolutionize early disease detection in a point-of-care setting and shrink test result wait times from weeks to minutes.

29 Aug 2012

Renal denervation safe and effective in patients with treatment resistant hypertension

Renal denervation leads to significant and sustained blood pressure reduction for up to 18 months in patients with treatment resistant hypertension, according to research presented at ESC Congress 2012.

27 Aug 2012

Debiopharm initiates enrollment in triptorelin phase III study for central precocious puberty

Debiopharm Group (Debiopharm), a Swiss-based global biopharmaceutical group of companies with a focus on the development of prescription drugs that target unmet medical needs and companion diagnostics, today announced that the first patient has been enrolled in an open-label phase III study to investigate the efficacy, safety, and pharmacokinetics of the sustained release triptorelin pamoate 22.5 mg 6-month-formulation in children with central precocious puberty (CPP), a rare disease.

27 Aug 2012

New device can measure mass of individual molecules one at a time

A team led by scientists at the California Institute of Technology (Caltech) have made the first-ever mechanical device that can measure the mass of individual molecules one at a time.

27 Aug 2012

Mexican-Americans with ancestral links have higher insulin resistance levels

Mexican-Americans with an ancestral link to Amerindian tribes were found to have higher insulin resistance levels, which is an indication of several chronic conditions such as type 2 diabetes, according to research by The University of Texas Health Science Center at Houston (UTHealth).

26 Aug 2012

Frequency News and Research

Zalicus commences first of two Z160 Phase 2a clinical studies for chronic neuropathic pain

Avanir initiates enrollment in AVP-923 Phase II clinical trial for treatment of agitation in AD patients

Closing large intracardiac shunts does not improve sleep apnea

Posterior medial cortex more specifically engaged in recall or imagination

Eat your greens for healthy sperm genes

Herpes virus eventually impairs glucose regulation

Novel scoring system shows sclerotherapy improves pain of venous malformation

Policymakers need to continue funding for adolescent smoking prevention programs: WSU

Link between sleep apnoea and overactive bladder syndrome in women

Stanford engineers demonstrate feasibility of super-small, implantable cardiac device

The safety of trainee surgeons: an interview with Prof Calvin Coffey

Tunes and T-shirts for cardiac rehabilitation

FDA approves Ironwood’s LINZESS to treat irritable bowel syndrome with constipation

Tunes and T-shirts for cardiac rehabilitation

Deep-brain stimulation may stop uncontrollable shaking in patients with Parkinson's

NYU-Poly creates ultra-sensitive biosensor to identify small single virus particles

Renal denervation safe and effective in patients with treatment resistant hypertension

Debiopharm initiates enrollment in triptorelin phase III study for central precocious puberty

New device can measure mass of individual molecules one at a time

Mexican-Americans with ancestral links have higher insulin resistance levels

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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