Genes News and Research

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Facets of SARS-CoV-2 infection and animal models

A new study in the journal Frontiers in Cell and Developmental Biology discusses the ribonucleic acid (RNA) genome of the virus, and the mechanisms by which it establishes infection within the host cell. The researchers also summarize the development of animal models of COVID-19, which will both help understand the clinical features of the illness, and indicate new approaches for the treatment of the infection.

21 May 2021

New study may lead to better treatments for prostate, ovarian, and breast cancers

Researchers at UVA Cancer Center have unveiled important new insights into how hormones known as androgens act on our cells – and the discovery could boost efforts to develop better treatments for prostate, ovarian and breast cancers.

21 May 2021

Study demonstrates the negative effects of HERV activation on human brain development

Since our ancestors infected themselves with retroviruses millions of years ago, we have carried elements of these viruses in our genes - known as human endogenous retroviruses, or HERVs for short.

21 May 2021

TIBI receives GFI grant to develop a unique, effective method of producing cultivated meat

The Terasaki Institute for Biomedical Innovation (TIBI) has been awarded a grant by The Good Food Institute (GFI) to develop a unique and effective method of producing cultivated meat, which is meat grown directly from the cell.

21 May 2021

Plastic chemicals can induce changes in gene that is vital for neurological development

The chemical bisphenol F (found in plastics) can induce changes in a gene that is vital for neurological development. This discovery was made by researchers at the universities of Uppsala and Karlstad, Sweden.

20 May 2021

Cancer occurs through multiple steps that resurrect ancient cellular functions, suggests new model

In spite of decades of research, cancer remains an enigma. Conventional wisdom holds that cancer is driven by random mutations that create aberrant cells that run amok in the body.

20 May 2021

Are COVID-19-related complications in children explained by abnormal immune responses?

A common theme in reports on COVID-19 around the world has been the large number of children who have not been infected or shown signs of disease. However, though the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes less acute infection in this age group, it is associated with a severe immune-mediated multisystemic illness called multisystem inflammatory syndrome in children (MIS-C).

20 May 2021

Scientists use anti-psychotics to treat flies displaying behavioral problems linked to schizophrenia-associated genes

Scientists have successfully treated flies displaying behavioral problems linked to newly discovered schizophrenia-associated genes in humans, using common anti-psychotics.

20 May 2021

Antithrombotic endothelial dysfunction is prevented by Tie2 activation in severe COVID-19

Researchers from the US recently assessed if severe COVID-19 is linked to procoagulant dysfunction of the endothelium and changes in the Tie2-angiopoietin axis. They assessed circulating endothelial markers in a study cohort of 98 patients with mild, moderate, or severe COVID-19. This study is published on the medRxiv* preprint server.

19 May 2021

Researchers use base editing to sustainably lower high LDL cholesterol levels

Base editing is a novel gene editing approach that can precisely change individual building blocks in a DNA sequence.

19 May 2021

Secondhand smoke during pregnancy linked to epigenetic changes in babies

Nearly a quarter of pregnant women say they've been around secondhand smoke - in their homes, at work, around a friend or relative - which, according to new research.

19 May 2021

Nasal epithelium in newborn infants express fewer receptors for SARS-CoV-2 than adults

A new report in the British Medical Journal indicates that newborns have a lower abundance of entry receptors for SARS-CoV-2.

19 May 2021

Nasal epithelium in newborn infants express fewer receptors for SARS-CoV-2 than adults

A new report in the British Medical Journal indicates that newborns have a lower abundance of entry receptors for SARS-CoV-2.

19 May 2021

Researchers find new clue to restore congenital hearing loss

Researchers at Oregon State University have found a key new piece of the puzzle in the quest to use gene therapy to enable people born deaf to hear.

19 May 2021

New study will help investigate innate immune responses to viral infections

Researchers from Boston University School of Medicine (BUSM) report the formation of human cells containing a green fluorescent protein or GFP (one of the most important proteins in biology and fluorescence imaging) genetically fused with two interferon stimulated genes (ISGs), namely Viperin and ISG15.

19 May 2021

Scientists develop experimental direct-acting antiviral therapy to treat COVID-19

An international team of scientists from the Menzies Health Institute Queensland (MHIQ) at Griffith University and from City of Hope, a research and treatment center for cancer, diabetes and other life-threatening diseases in the U.S., have developed an experimental direct-acting antiviral therapy to treat COVID-19.

18 May 2021

New coronavirus test can get fast, accurate results from saliva samples

A new coronavirus test can get accurate results from a saliva sample in less than 30 minutes, researchers report in the journal Nature Communications.

18 May 2021

Researchers link “genetic signatures” of bacteria in the human gut to multiple diseases

We are truly never alone, not even within our own bodies. Human beings play host to trillions of bacteria, fungi, viruses, and other microorganisms that make up the human microbiome.

18 May 2021

Researchers investigate immune molecule that helps protect transplanted kidneys

Looking to improve organ transplant success, researchers are working to learn more about how an immune molecule, which also protects a fetus, helps protect some transplanted kidneys, and to develop a synthetic version of that molecule that could help more patients.

18 May 2021

A promising drug delivery system for therapeutics that shut down harmful genes

Viruses attack the body by sending their genetic code -- DNA and RNA -- into cells and multiplying. A promising class of therapeutics that uses synthetic nucleic acids to target and shut down specific, harmful genes and prevent viruses from spreading is gaining steam.

18 May 2021

Genes News and Research

Facets of SARS-CoV-2 infection and animal models

New study may lead to better treatments for prostate, ovarian, and breast cancers

Study demonstrates the negative effects of HERV activation on human brain development

TIBI receives GFI grant to develop a unique, effective method of producing cultivated meat

Plastic chemicals can induce changes in gene that is vital for neurological development

Cancer occurs through multiple steps that resurrect ancient cellular functions, suggests new model

Are COVID-19-related complications in children explained by abnormal immune responses?

Scientists use anti-psychotics to treat flies displaying behavioral problems linked to schizophrenia-associated genes

Antithrombotic endothelial dysfunction is prevented by Tie2 activation in severe COVID-19

Researchers use base editing to sustainably lower high LDL cholesterol levels

Secondhand smoke during pregnancy linked to epigenetic changes in babies

Nasal epithelium in newborn infants express fewer receptors for SARS-CoV-2 than adults

Nasal epithelium in newborn infants express fewer receptors for SARS-CoV-2 than adults

Researchers find new clue to restore congenital hearing loss

New study will help investigate innate immune responses to viral infections

Scientists develop experimental direct-acting antiviral therapy to treat COVID-19

New coronavirus test can get fast, accurate results from saliva samples

Researchers link “genetic signatures” of bacteria in the human gut to multiple diseases

Researchers investigate immune molecule that helps protect transplanted kidneys

A promising drug delivery system for therapeutics that shut down harmful genes

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