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Researchers identify striking contrasts in how groups of neurons function during decision making

By training mice to perform a sound identification task in a virtual reality maze, researchers at Harvard Medical School and the Istituto Italiano di Tecnologia (IIT) have identified striking contrasts in how groups of neurons in different cortex regions of the brain function during decision making.

19 Jul 2017

Study shows how cancer cells force normal cells to act like viruses to enable tumor growth

In a study that could explain why some breast cancers are more aggressive than others, researchers say they now understand how cancer cells force normal cells to act like viruses – allowing tumors to grow, resist treatment, and spread.

19 Jul 2017

Study shows variation in testosterone prescribing practices in VA system

Providers in the Veterans Health Administration (VA) system vary in their testosterone prescribing practices, according to a study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism.

19 Jul 2017

Highly intricate visual system arises from simple blueprint present at birth, findings suggest

For decades, researchers have known that the primate brain is organized into "maps" for each of the different senses: one of the body for touch, one of the visual world for sight, one of tones for hearing.

19 Jul 2017

Genetic therapy for two inherited neurologic diseases moves closer to human clinical trials

Researchers at University of Massachusetts Medical School and Auburn University College of Veterinary Medicine are nearing human clinical trials on a genetic therapy for two rare neurological diseases that are fatal to children.

19 Jul 2017

Pain relief, functional outcomes after joint replacement similar in obese and normal-weight patients

There's good news from UMass Medical School for overweight people with painfully arthritic hips and knees: A new study finds that obese patients who underwent knee or hip replacement surgery reported virtually the same pain relief and improved function as normal-weight joint replacement patients six months after surgery.

19 Jul 2017

Maternal pre-pregnancy obesity linked to increased risk for neurocognitive problems in preterm infants

A new study has found that children born extremely premature to women who are overweight or obese before the pregnancy are at an increased risk for low scores on tests of intelligence and cognitive processes that influence self-regulation and control, according to researchers at Wake Forest Baptist Medical Center.

18 Jul 2017

New antibiotic-releasing polymer may simplify treatment of prosthetic joint infection

A team of Massachusetts General Hospital investigators has developed an antibiotic-releasing polymer that may greatly simplify the treatment of prosthetic joint infection.

18 Jul 2017

Researchers discover gene mutations that worsen respiratory infections among children

Researchers funded by the Swiss National Science Foundation have discovered mutations that worsen respiratory infections among children. Their study explains the mechanism involved.

18 Jul 2017

New analysis compares emerging algorithms that look for cancer mutations

Sanford Burnham Prebys Medical Discovery Institute has undertaken the first-ever comparative analysis of a newly emerging category of algorithms that mine genetic information in cancer databases by focusing on internal gene structure (subgene resolution algorithms), in contrast to classical approaches that focus on genes treated as single units.

17 Jul 2017

Mutations arising after conception may play vital role in autism

A study of nearly 6,000 families, combining three genetic sequencing technologies, finds that mutations that occur after conception play an important role in autism.

17 Jul 2017

Regular word puzzle use linked to better brain function in later life

The more regularly people report doing word puzzles such as crosswords, the better their brain function in later life, a large-scale and robust online trial has found.

17 Jul 2017

ASU-TGen researchers find source of altered ANK1 gene expression linked to Alzheimer's disease

Researchers led by Arizona State University and the Translational Genomics Research Institute have identified altered expression of a gene called ANK1, which only recently has been associated with memory robbing Alzheimer's disease, in specific cells in the brain.

14 Jul 2017

MGH researchers identify novel mechanism behind resistance to angiogenesis inhibitors

A Massachusetts General Hospital research team has identified a novel mechanism behind resistance to angiogenesis inhibitors - drugs that fight cancer by suppressing the formation of new blood vessels.

14 Jul 2017

New framework analyzes ecological, economic and epidemiological factors of rural poverty

Deep in landlocked Africa, a miracle is unfolding. Less than a generation after a genocidal civil war left it in ruins, Rwanda is defying poverty traps that ensnare many other natural resource-dependent developing countries.

14 Jul 2017

Researchers discover new role of enzyme in promoting self-destruction of axons

Scientists in the Vollum Institute at OHSU have identified an enzyme that plays a crucial role in the degeneration of axons, the threadlike portions of a nerve cell that transmit signals within the nervous system.

14 Jul 2017

Mayo Clinic and nference launch startup to develop drugs for rare diseases

Today, Mayo Clinic and nference launch a startup company for drug development that will be powered by clinical expertise and artificial intelligence (AI).

14 Jul 2017

Prior dengue fever in people infected by Zika does not lead to worse illness

Individuals who are infected by Zika virus after having dengue fever do not appear to become more severely ill than people with Zika who have never had dengue.

14 Jul 2017

University of Warwick receives multi-million pound grant to improve healthcare in slums

The University of Warwick is to receive more than £5 million to find better ways of delivering healthcare to some of the world's poorest people.

14 Jul 2017

Scientists uncover new group of Treg cells and DNA features linked to juvenile idiopathic arthritis

A team of scientists and doctors from the SingHealth Duke-NUS Academic Medical Centre has uncovered a new group of regulatory T (Treg) cells and DNA features associated with juvenile idiopathic arthritis (JIA), the most common form of arthritis among children under the age of 16.

14 Jul 2017

Medical School News and Research

Researchers identify striking contrasts in how groups of neurons function during decision making

Study shows how cancer cells force normal cells to act like viruses to enable tumor growth

Study shows variation in testosterone prescribing practices in VA system

Highly intricate visual system arises from simple blueprint present at birth, findings suggest

Genetic therapy for two inherited neurologic diseases moves closer to human clinical trials

Pain relief, functional outcomes after joint replacement similar in obese and normal-weight patients

Maternal pre-pregnancy obesity linked to increased risk for neurocognitive problems in preterm infants

New antibiotic-releasing polymer may simplify treatment of prosthetic joint infection

Researchers discover gene mutations that worsen respiratory infections among children

New analysis compares emerging algorithms that look for cancer mutations

Mutations arising after conception may play vital role in autism

Regular word puzzle use linked to better brain function in later life

ASU-TGen researchers find source of altered ANK1 gene expression linked to Alzheimer's disease

MGH researchers identify novel mechanism behind resistance to angiogenesis inhibitors

New framework analyzes ecological, economic and epidemiological factors of rural poverty

Researchers discover new role of enzyme in promoting self-destruction of axons

Mayo Clinic and nference launch startup to develop drugs for rare diseases

Prior dengue fever in people infected by Zika does not lead to worse illness

University of Warwick receives multi-million pound grant to improve healthcare in slums

Scientists uncover new group of Treg cells and DNA features linked to juvenile idiopathic arthritis

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

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