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Low levels of BRCA1 protein in the brain linked to dementia

Mutant forms of breast cancer factor 1 (BRCA1) are associated with breast and ovarian cancers but according to new findings, in the brain the normal BRCA1 gene product may also be linked to Alzheimer's disease. The results, published in Nature Communications, suggest that low levels of BRCA1 protein in the brain may contribute to dementia.

1 Dec 2015

DNA sequence variation can influence gene activity in developing human brain

An international research collaboration has shed new light on how DNA sequence variation can influence gene activity in the developing human brain.

1 Dec 2015

Pre-existing asthma may strongly predict future chronic migraine attacks

Pre-existing asthma may be a strong predictor of future chronic migraine attacks in individuals experiencing occasional migraine headaches, according to researchers from the University of Cincinnati, Montefiore Headache Center and Albert Einstein College of Medicine, and Vedanta Research.

30 Nov 2015

Discovery opens up new avenue for research on potential treatments for Alzheimer's disease

A team of researchers led by UNSW Australia scientists has discovered how connections between brain cells are destroyed in the early stages of Alzheimer's disease - work that opens up a new avenue for research on possible treatments for the degenerative brain condition.

27 Nov 2015

New study reveals effect of cannabis potency on brain structure

Smoking high potency 'skunk-like' cannabis can damage a crucial part of the brain responsible for communication between the two brain hemispheres, according to a new study by scientists from King's College London and Sapienza University of Rome.

27 Nov 2015

Oxytocin hormone strengthens social ties

Nowadays, much emphasis is placed on sustainability. The degree to which people are willing to donate their own money for this depends on their level of oxytocin. Scientists at the University of Bonn Hospital have discovered that the willingness to donate increases with the quantity of this bonding hormone. However, oxytocin only has an effect with regard to social sustainability projects. The hormone does not increase the ability to participate in the case of purely environmentally oriented projects.

26 Nov 2015

Chikungunya may cause severe brain infection

The mosquito-borne virus chikungunya may lead to severe brain infection and even death in infants and people over 65, according to a new study that reviewed a chikungunya outbreak on Reunion Island off the coast of Madagascar in 2005-2006.

26 Nov 2015

New drug may show promise against resistant melanomas

A new drug discovered by scientists at Sanford Burnham Prebys Medical Discovery Institute may show promise for treating skin cancers that are resistant or unresponsive to today's leading therapies.

25 Nov 2015

Allergan, Rugen Therapeutics collaborate to discover and develop novel therapies for ASD and OCD

Allergan plc, a leading global pharmaceutical company, and Rugen Therapeutics, a start-up biotechnology company focused on the development of novel treatments for unmet CNS disorders and funded by the F-Prime Biomedical Research Initiative, today announced that they have entered into an exclusive collaboration to support the discovery and development of novel therapies for Autism Spectrum Disorders (ASD) and Obsessive Compulsive disorders (OCD).

25 Nov 2015

Physical exercise can enhance development of new brain cells

Exercise can enhance the development of new brain cells in the adult brain, a process called adult neurogenesis. These newborn brain cells play an important role in learning and memory. A new study has determined that mice that spent time running on wheels not only developed twice the normal number of new neurons, but also showed an increased ability to distinguish new objects from familiar objects.

25 Nov 2015

People with chronic fatigue syndrome could experience higher levels of visual stress

People suffering from Chronic Fatigue Syndrome (CFS) could experience higher levels of visual stress than those without the condition, according to new research from the University of Leicester.

25 Nov 2015

High-fat diet appears to prompt immune cells to start consuming connections between neurons

When a high-fat diet causes us to become obese, it also appears to prompt normally bustling immune cells in our brain to become sedentary and start consuming the connections between our neurons, scientists say.

24 Nov 2015

Neurodata Without Borders provides common format for brain data

An alliance of brain researchers and funders has announced a common data format to facilitate the free and open exchange of complex information about the brain--information that scientists can then use to accelerate progress in understanding the brain and developing new treatments for brain disorders.

23 Nov 2015

Addition of sugar molecules to particular proteins vital for plants in basic developmental processes

Adding a spoonful of sugar to coffee makes it sweeter, but in plants, researchers have discovered, the addition of sugar molecules to particular proteins plays a surprising variety of roles in basic developmental processes.

23 Nov 2015

Protein aggregates as harmful as neurodegenerative-disease-related proteins, shows study

Scientists at the forefront of cutting-edge research into neurodegenerative diseases such as Alzheimer’s and Parkinson’s have shown that the mere presence of protein aggregates may be as important as their form and identity in inducing cell death in brain tissue.

20 Nov 2015

UF Health investigators make new discovery about Huntington's disease

University of Florida Health researchers have made a new discovery about Huntington's disease, showing that the gene that causes the fatal disorder makes an unexpected "cocktail" of mutant proteins that accumulate in the brain.

19 Nov 2015

Researchers find mechanism to repair communication between neurons

A team of researchers led by professor Patrik Verstreken (VIB/KU Leuven) has exposed the fine details of a mechanism that provides more insight in the communication between neurons. The research has clarified how damaged synapses - the connection points between neurons - are repaired to keep communication between neurons at an optimal level.

19 Nov 2015

Gestational diabetes mellitus screening provides more health benefits to pregnant women

A local research study conducted by KK Women's and Children's Hospital and Duke-NUS Graduate Medical School has found that pregnant patients benefit most from gestational diabetes mellitus (GDM) screening as it allows for timely interventions and brings about health benefits that far outweigh the cost.

18 Nov 2015

Structural differences in key brain region linked to hallucinations in people diagnosed with schizophrenia

People diagnosed with schizophrenia who are prone to hallucinations are likely to have structural differences in a key region of the brain compared to both healthy individuals and people diagnosed with schizophrenia who do not hallucinate, according to research published today.

17 Nov 2015

Researchers identify molecular patterns that dominate gene expression in the human brain

The human brain may be the most complex piece of organized matter in the known universe, but Allen Institute researchers have begun to unravel the genetic code underlying its function. Research published this month in Nature Neuroscience identified a surprisingly small set of molecular patterns that dominate gene expression in the human brain and appear to be common to all individuals, providing key insights into the core of the genetic code that makes our brains distinctly human.

17 Nov 2015

Neuroscience News and Research

Low levels of BRCA1 protein in the brain linked to dementia

DNA sequence variation can influence gene activity in developing human brain

Pre-existing asthma may strongly predict future chronic migraine attacks

Discovery opens up new avenue for research on potential treatments for Alzheimer's disease

New study reveals effect of cannabis potency on brain structure

Oxytocin hormone strengthens social ties

Chikungunya may cause severe brain infection

New drug may show promise against resistant melanomas

Allergan, Rugen Therapeutics collaborate to discover and develop novel therapies for ASD and OCD

Physical exercise can enhance development of new brain cells

People with chronic fatigue syndrome could experience higher levels of visual stress

High-fat diet appears to prompt immune cells to start consuming connections between neurons

Neurodata Without Borders provides common format for brain data

Addition of sugar molecules to particular proteins vital for plants in basic developmental processes

Protein aggregates as harmful as neurodegenerative-disease-related proteins, shows study

UF Health investigators make new discovery about Huntington's disease

Researchers find mechanism to repair communication between neurons

Gestational diabetes mellitus screening provides more health benefits to pregnant women

Structural differences in key brain region linked to hallucinations in people diagnosed with schizophrenia

Researchers identify molecular patterns that dominate gene expression in the human brain

Event guide: 2nd Neuroscience Innovation Partnering & Licensing Summit eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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