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Research reports full efficacy of Sotrovimab against BQ.1.1 viral replication in a non-human primate challenge model

Researchers used a non-human primate model to show that Sotrovimab, a commercial mAb also known as Xevudy, was fully effective against SARS-CoV-2 Omicron BA.5 sub-lineage and its derivatives, such as BQ.1.1.

17 Feb 2023

CHLA researchers receive funding to support studies into diffuse intrinsic pontine glioma

Researchers at Children's Hospital Los Angeles have received a nearly $1 million K08 grant from the National Institutes of Health (NIH) - as well as funding from the U.S. Department of Defense - to support studies into diffuse intrinsic pontine glioma (DIPG), a childhood brain tumor with a 0% survival rate.

16 Feb 2023

Small molecule inhibitor reverses malignant hyper-editing by an inflammation-induced protein isoform

Researchers at University of California San Diego School of Medicine, Sanford Stem Cell Institute and Moores Cancer Center report that a late-stage, pre-clinical small molecule inhibitor, called rebecsinib, reverses malignant hyper-editing by an inflammation-induced protein isoform, known as ADAR1 p150.

16 Feb 2023

Penn engineers address the longstanding gap in reproductive health care with targeted RNA therapy

Pre-eclampsia is a leading cause of stillbirths and prematurity worldwide, occurring in 3 – 8 % of pregnancies. A disorder characterized by high maternal blood pressure, it results from insufficient vasodilation in the placenta, restricting blood flow from the mother to the fetus.

16 Feb 2023

A call to action proposed for health providers to ensure widest distribution, easy availability of naloxone

In 2021, 100,306 Americans died from drug overdoses – a 28.5 percent increase from the prior year – with 75,673 attributed to opioids.

16 Feb 2023

Repurposing or improving drugs for spinocerebellar ataxia type 5

A team of researchers has developed a new method to screen FDA-approved drugs to determine if they could be repurposed or improved to help patients with a rare, debilitating disease of the nervous system.

16 Feb 2023

Cohort study examines the incidence of SARS-CoV-2 rebound in patients on oral antivirals

Researchers performed a retrospective population-wide cohort study using anonymized data in Hong Kong, China, between February 26 and July 3, 2022.

16 Feb 2023

Study highlights the interconnectedness of autoimmunity and cancer

In a recent study published in the journal Immunity, researchers reviewed the T cell response in cancer and autoimmunity to propose strategies for more effective immunotherapies.

15 Feb 2023

Nirmatrelvir-ritonavir therapy effective against Omicron BA.4/BA.5

Researchers examine non-hospitalized adult patients with COVID-19 treated with nirmatrelvir-ritonavir.

15 Feb 2023

Centrosome regulates nerve cell migration, study finds

Researchers from the DZNE have solved an important puzzle in neurobiology: the wiring and the movement of nerve cells are interwoven, but separately controlled.

15 Feb 2023

Increasing numbers of cancer survivors at high risk for cardiovascular disease

American Cancer Society (ACS) research estimates there are more than 18 million adult survivors of cancer in the United States, and that number is expected to climb to more than 22 million by 2030.

15 Feb 2023

What is the tolerability profile and rate of recurrent CDI after administrating microbiome therapeutic SER-109 post-antibiotic treatment?

Researchers investigated the tolerability and safety of a microbiome therapy called SER-109 to treat recurrent infections of Clostridioides difficile in adults.

15 Feb 2023

How does previous diet impact the endocannabinoidome and microbiome response to a short-term Mediterranean diet intervention?

Researchers assessed the different impacts of diet on the gut microbiome.

15 Feb 2023

NIH initiates a clinical trial evaluating an investigational antiviral for treatment of COVID-19

The National Institutes of Health has initiated a multi-site clinical trial evaluating an investigational antiviral for the treatment of COVID-19.

15 Feb 2023

Integrating AI with infrared imaging to improve colon cancer diagnosis

Artificial intelligence and infrared imaging automatically classify tumors and are faster than previous methods.

14 Feb 2023

Enhanced prediction of prostate cancer recurrence using machine learning model

Predicting the course of prostate cancer is challenging because only a fraction of prostate cancer patients experience recurrence after radical prostatectomy or radiation therapy.

14 Feb 2023

The efficiency of lifestyle intervention, orlistat, and experimental diet therapy in patients with obesity and metabolic-associated fatty liver disease

Researchers compared the effects of an experimental low-carbohydrate and high-protein diet and orlistat with that of a control diet to examine their impact on Asian MAFLD patients with obesity.

14 Feb 2023

Cabometyx® in combination with nivolumab shows durable survival benefits at over three-years’ follow-up in first-line advanced renal cell carcinoma

Ipsen (Euronext: IPN; ADR: IPSEY) today announced three-year minimum, 44-month median, follow-up results from the Phase III CheckMate -9ER trial showing that Cabometyx® (cabozantinib) in combination with nivolumab provides survival and response rate benefits after three-years in the first-line treatment of advanced renal cell carcinoma (aRCC), compared to sunitinib.

From Ipsen 14 Feb 2023

How Can Companies Bring New AI Software Medical Devices to Market?

For SLAS US 2023, we speak to Guy Starbuck, a co-founder of AIQ Global, about how we can utilize AI technology to bring new medical devices to market.

From AIQ Solutions 14 Feb 2023

Over 50% of cancer patients report long COVID symptoms after recovering from COVID-19

Tesearchers investigate the persistent symptoms experienced by cancer patients who previously recovered from COVID-19.

13 Feb 2023

Therapy News and Research

Research reports full efficacy of Sotrovimab against BQ.1.1 viral replication in a non-human primate challenge model

CHLA researchers receive funding to support studies into diffuse intrinsic pontine glioma

Small molecule inhibitor reverses malignant hyper-editing by an inflammation-induced protein isoform

Penn engineers address the longstanding gap in reproductive health care with targeted RNA therapy

A call to action proposed for health providers to ensure widest distribution, easy availability of naloxone

Repurposing or improving drugs for spinocerebellar ataxia type 5

Cohort study examines the incidence of SARS-CoV-2 rebound in patients on oral antivirals

Study highlights the interconnectedness of autoimmunity and cancer

Nirmatrelvir-ritonavir therapy effective against Omicron BA.4/BA.5

Centrosome regulates nerve cell migration, study finds

Increasing numbers of cancer survivors at high risk for cardiovascular disease

What is the tolerability profile and rate of recurrent CDI after administrating microbiome therapeutic SER-109 post-antibiotic treatment?

How does previous diet impact the endocannabinoidome and microbiome response to a short-term Mediterranean diet intervention?

NIH initiates a clinical trial evaluating an investigational antiviral for treatment of COVID-19

Integrating AI with infrared imaging to improve colon cancer diagnosis

Enhanced prediction of prostate cancer recurrence using machine learning model

The efficiency of lifestyle intervention, orlistat, and experimental diet therapy in patients with obesity and metabolic-associated fatty liver disease

Cabometyx® in combination with nivolumab shows durable survival benefits at over three-years’ follow-up in first-line advanced renal cell carcinoma

How Can Companies Bring New AI Software Medical Devices to Market?

Over 50% of cancer patients report long COVID symptoms after recovering from COVID-19

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

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