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Berkeley Lab scientists reveal how protein-making machine bends without breaking

It sounds like hype from a late-night infomercial: It can twist and bend without breaking! And wait, there's more: It could someday help you fend off disease!

20 May 2011

International team identifies key protein in development of drug-resistant leukemia

Now an international team led by researchers at the University of California, San Francisco and joined by scientists of the Freiburg excellence cluster BIOSS - Centre for Biological Signalling Studies, has identified a protein called BCL6 which plays a key role in the development of drug-resistance in leukemia.

20 May 2011

Cholesterol drug may help treat mitochondrial diseases

A human drug that both prevents and cures kidney failure in mice sheds light on disabling human mitochondrial disorders, and may represent a potential treatment in people with such illnesses.

20 May 2011

Surgeon's choices and choice of surgeons influence hospital charges for spinal fusion surgery

Hospital charges for spinal fusion surgery in the upper spine vary considerably—with the surgeon's choice of spinal hardware being the largest source of variation, reports a study in the May 15 issue of Spine.

20 May 2011

Complementary and alternative health practices show promise for management of pain

A variety of complementary and alternative health practices —including meditation and relaxation techniques, manual therapies such as massage and spinal manipulation, meditative exercise forms such as yoga, Tai Chi, and ancient health practices such as acupuncture—show promise for contributing to the management of pain according to research presented at the Annual Scientific Meeting of the American Pain Society, www.ampainsoc.org.

20 May 2011

Bayer, Onyx to present Nexavar-chemotherapy combination Phase 2b trial data in breast cancer at ASCO 2011

Bayer HealthCare Pharmaceuticals, Inc. and Onyx Pharmaceuticals, Inc. today announced results from a Phase 2b trial evaluating Nexavar® (sorafenib) tablets in patients with locally advanced or metastatic breast cancer previously treated with a bevacizumab-containing regimen, which showed that Nexavar was associated with statistically significant improvements in progression-free survival and time-to-progression.

20 May 2011

Naltrexone improves clinical, inflammatory activity in Crohn's disease patients

Naltrexone reduced inflammation in Crohn's patients in a research study at Penn State College of Medicine.

20 May 2011

Longer looks: Tough health care questions for GOP presidential contenders; Robotics help spike use of prostate treatment

For my money, the most interesting thing about Mitt Romney's health-care speech last week wasn't his struggle to defend Romneycare and distance it from Obamacare, but the largely hostile reception of the speech from the right.

20 May 2011

Viewpoints: Coburn on his dropout; Malpractice reform and states

For the past several months I have been meeting with a small group of senators from both parties, informally known as the Gang of Six, that was designed to force the idle — not gridlocked — Senate, and then the House and the president, to enact a long-term deficit-reduction package.

20 May 2011

Medical food resolves metabolic syndrome and cardiovascular risk factors

Researchers at the University of Florida and Metagenics Inc. today announced that a program consisting of a breakthrough medical food combined with a low-glycemic, Mediterranean-style diet is almost twice as effective as one of the best diets alone for lowering risk factors for cardiovascular disease, the leading cause of death in the U.S.

19 May 2011

PolyMedix's PMX-30063 compound mitigates ulcerative mucositis in pre-clinical studies

PolyMedix, Inc., a biotechnology company focused on developing new therapeutic drugs to treat patients with acute infectious diseases and cardiovascular disorders, announced today that its lead defensin-mimetic antibiotic compound, PMX-30063, when administered topically as an oral rinse, has shown activity against oral mucositis in an animal study.

19 May 2011

Free NYU Physician iPad app now available in iTunes store

NYU Langone Medical Center, one of the nation's premier academic medical centers, announced today the magazine of NYU School of Medicine, NYU Physician, is now available as a free iPad app in the iTunes App Store.

19 May 2011

Sensitive troponin assays improve clinical outcome and cardiac patient management

Research presented this week at the International Federation of Clinical Chemistry Congress and Laboratory Medicine showed that using a lower diagnostic threshold for troponin improves clinical outcomes and patient survival in patients with suspected acute coronary syndromes.

19 May 2011

Hospital websites use industry-provided content and overestimate claims of surgical robots

An estimated four in 10 hospital websites in the United States publicize the use of robotic surgery, with the lion's share touting its clinical superiority despite a lack of scientific evidence that robotic surgery is any better than conventional operations, a new Johns Hopkins study finds.

19 May 2011

Study: 10% of cancer patients fail to fill initial oral oncolytic prescriptions

Ten percent of cancer patients failed to fill their initial prescriptions for oral anti-cancer drugs, according to a new study published jointly today in the Journal of Oncology Practice and American Journal of Managed Care.

19 May 2011

Humanized BLT mice help prevent HIV/AIDS transmission

The more than 2.7 million new HIV infections recorded per year leave little doubt that the HIV/AIDS epidemic continues to spread globally. That's why there's the need for safe, inexpensive and effective drugs to successfully block HIV transmission.

19 May 2011

Takeda reaches agreement to acquire Nycomed

Takeda Pharmaceutical Company Limited and Nycomed A/S jointly announced today that Takeda has reached an agreement with the shareholders of Nycomed in which Takeda will acquire the Zurich-headquartered company for 9.6 billion Euro on a cash-free, debt-free basis.

19 May 2011

Pitt researchers develop mouse model of major depressive disorder

Researchers at the University of Pittsburgh School of Medicine have developed a mouse model of major depressive disorder (MDD) that is based on a rare genetic mutation that appears to cause MDD in the majority of people who inherit it.

19 May 2011

NEW Lifestyle on-line teaching modules for medical students

Obesity is an epidemic and when paired with physical inactivity it represents the second leading cause of preventable death nationally from cancer, cardiovascular diseases and diabetes. But in medical school, there is a training gap when it comes to teaching future doctors about obesity and related health problems.

19 May 2011

Silence to present new Atu027 Phase I study data in advanced solid tumors at ASCO annual meeting

Silence Therapeutics plc, a leading global RNA interference therapeutics company, announces that it will present new data from its ongoing Phase I study of Atu027, its lead internal therapeutic candidate, at the 2011 American Society of Clinical Oncology Annual Meeting on 06 June 2011.

19 May 2011

Medicine News and Research

Berkeley Lab scientists reveal how protein-making machine bends without breaking

International team identifies key protein in development of drug-resistant leukemia

Cholesterol drug may help treat mitochondrial diseases

Surgeon's choices and choice of surgeons influence hospital charges for spinal fusion surgery

Complementary and alternative health practices show promise for management of pain

Bayer, Onyx to present Nexavar-chemotherapy combination Phase 2b trial data in breast cancer at ASCO 2011

Naltrexone improves clinical, inflammatory activity in Crohn's disease patients

Longer looks: Tough health care questions for GOP presidential contenders; Robotics help spike use of prostate treatment

Viewpoints: Coburn on his dropout; Malpractice reform and states

Medical food resolves metabolic syndrome and cardiovascular risk factors

PolyMedix's PMX-30063 compound mitigates ulcerative mucositis in pre-clinical studies

Free NYU Physician iPad app now available in iTunes store

Sensitive troponin assays improve clinical outcome and cardiac patient management

Hospital websites use industry-provided content and overestimate claims of surgical robots

Study: 10% of cancer patients fail to fill initial oral oncolytic prescriptions

Humanized BLT mice help prevent HIV/AIDS transmission

Takeda reaches agreement to acquire Nycomed

Pitt researchers develop mouse model of major depressive disorder

NEW Lifestyle on-line teaching modules for medical students

Silence to present new Atu027 Phase I study data in advanced solid tumors at ASCO annual meeting

Everything there is to know about biosimilars eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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