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Fizzy tablet is best method to receive fentanyl for cancer pain

Results of a mixed treatment comparison show that fentanyl in the form of an effervescent buccal tablet can better relieve the intensity of breakthrough cancer pain in the first 60 minutes after dosing compared with other fentanyl formulations.

23 Aug 2012

Agenda now available for Transcatheter Cardiovascular Therapeutics symposium

TCT 2012 (Transcatheter Cardiovascular Therapeutics), the annual scientific symposium of the Cardiovascular Research Foundation will provide significant clinical research updates to technologies and practices in interventional cardiology that will directly affect patient care.

23 Aug 2012

State roundup: Restraining order issued in Mo. health exchange fight

A judge issued a temporary restraining order Tuesday against Missouri's secretary of state, Robin Carnahan, to prevent her from finalizing the language of a ballot question on health insurance exchanges. Lt. Gov. Peter Kinder, a Republican, sought the restraining order while a state court considers whether the language of the ballot question is biased, a claim leveled by Kinder and the state's top Republicans.

23 Aug 2012

Scientists report discovery of strong oral cavity carcinogen in smokeless tobacco

Scientists today reported identification of the first substance in smokeless tobacco that is a strong oral carcinogen ― a health risk for the 9 million users of chewing tobacco, snuff and related products in the U.S. ― and called upon the federal government to regulate or ban the substance.

23 Aug 2012

MR enterography performs well in children with Crohn disease

Parents with children nine years old and older who have Crohn disease should ask their children's doctor about MR enterography as a replacement for small bowel x-rays or CT enterography, a new study indicates.

23 Aug 2012

Emotional health and education level of mothers influence teen’s oral health

A mother's emotional health and education level during her child's earliest years influence oral health at age 14, according to a new study from Case Western Reserve University's School of Dental Medicine.

23 Aug 2012

Schizophrenia patients benefit from text message reminders

A text message-based service may help improve medication adherence in patients with schizophrenia, researchers report.

22 Aug 2012

Surgeons should not resist rectal resection in endometriosis

Rectal resection for deeply infiltrating endometriosis can be performed with limited morbidity, say the authors of an Australian study.

22 Aug 2012

Surface electromyography can rehabilitate muscles in children with cranial nerve palsy

A child's smile is something we take for granted. But muscle dysfunction can turn a simple expression of joy into a challenge. Surface electromyography provides a noninvasive method of sensing muscle activity that can be used for muscle rehabilitation—and to bring a smile to a child's face.

22 Aug 2012

Clinical trial to test whether fecal transplantation is effective in treating relapsing C. difficile

For patients with Clostridium difficile (C. difficile), a persistent and potentially deadly bacterial illness, severe diarrhea, abdominal pain, nausea and vomiting are an everyday event. This particularly virulent infection is prone to recurrence, even after multiple courses of expensive antibiotics, and treatment options are limited for patients who continually relapse or develop antibiotic resistance.

22 Aug 2012

FDA extends action date for Pfizer’s tofacitinib NDA review

Pfizer Inc. announced today that the U.S. Food and Drug Administration (FDA) has extended the action date by three months for the New Drug Application (NDA) for tofacitinib, an investigational oral treatment for adults with moderately to severely active rheumatoid arthritis (RA).

22 Aug 2012

International guidelines improve outcomes after dental trauma

Adhering to the current International Association of Dental Traumatology guidelines for emergency treatment and care of traumatized teeth results in significantly lower complication rates, report researchers in Clinical Oral Investigations.

21 Aug 2012

Methyl-glyoxal could play a major role in abdominal obesity, insulin resistance and type 2 diabetes

Researchers at Mount Sinai School of Medicine have identified a common compound in the modern diet that could play a major role in the development of abdominal obesity, insulin resistance, and type 2 diabetes.

21 Aug 2012

PD risk factors for potential clinical screening identified

A meta-analysis has identified 19 risk factors that significantly impact a person’s risk for Parkinson’s disease and could be of potential value for clinical screening, say the authors.

20 Aug 2012

Injectable controlled-release capsules against gum disease

Scientists are trying to open a new front in the battle against gum disease, the leading cause of tooth loss in adults and sometimes termed the most serious oral health problem of the 21st century. They described another treatment approach for the condition in a report here today at the 244th National Meeting & Exposition of the American Chemical Society, the world's largest scientific society.

20 Aug 2012

HRT linked to ulcerative colitis in postmenopausal women

Taking postmenopausal hormone replacement therapy increases the risk for ulcerative colitis, but not Crohn’s disease, a study shows.

17 Aug 2012

Ranbaxy’s generic pioglitazone hydrochloride tablets now available in the U.S.

Ranbaxy Pharmaceuticals Inc., a wholly owned subsidiary of Ranbaxy Laboratories Ltd. (RLL), has launched authorized generic pioglitazone hydrochloride tablets in the U.S. market, under an agreement with Takeda Pharmaceuticals U.S.A., Inc.

17 Aug 2012

Mepolizumab almost halves exacerbations in severe asthma patients

The largest study of patients with severe asthma to date, published in The Lancet special issue on respiratory medicine, shows that those treated with the monoclonal antibody mepolizumab experienced an almost 50% reduction in severe exacerbations, emergency room visits, and hospitalisations compared with patients given placebo.

17 Aug 2012

Blog examines administration of zinc, rehydration salts to treat diarrhea in rural India

In this post in the PLoS "Speaking of Medicine" blog, guest blogger Oliver Sabot, executive vice president of the Clinton Health Access Initiative, "reflects on the challenge and opportunity of scaling-up access to effective treatment for diarrhea, the second largest cause of child mortality globally."

17 Aug 2012

Montelukast improves respiratory disturbance and adenoid size in children with OSA

Ben-Gurion University of the Negev (BGU) researchers revealed that a majority of children suffering from Obstructive Sleep Apnea (OSA) treated with montelukast, a drug approved for asthma or hay fever, showed significant improvement in respiratory disturbance and adenoid size, according to a new study published in Pediatrics Journal.

17 Aug 2012