Protein C News and Research

RSS

Researchers design a COVID-19 vaccine construct using hybrid SARS-CoV-2 spike protein and nucleocapsid protein peptides

Researchers designed a COVID-19 vaccine construct using hybrid SARS-CoV-2 S protein (containing SARS-CoV-2 Delta and Omicron variant mutations) and N protein peptides that confer T lymphocyte-mediated immune protection.

25 Oct 2022

Study reveals how SARS-CoV-2 infection of macrophages promotes inflammatory responses

Dysregulation of macrophages during SARS-CoV-2 infection and the over-exuberant production of pro-inflammatory cytokines by these macrophages has been hypothesized to contribute to severity of COVID-19 disease.

25 Oct 2022

Novel oxytocin derivative can reverse Aβ25-35-induced cognitive impairment in mice

Alzheimer's disease (AD), characterized by an accumulation of β-amyloid protein (Aβ) in brain tissue, is a leading cause of dementia.

24 Oct 2022

Variations in low-complexity regions in monkeypox genome found to impact virus transmissibility

In a new study, researchers investigated whether low-complexity regions (LCRs) were more accountable for the current 2022 IIb clade monkeypox (MPX) virus (MPXV) outbreak rather than single-nucleotide polymorphisms (SNPs).

24 Oct 2022

Bovine ultralong complementarity-determining region H3 found to cross-react with sarbecoviruses

In a new study, researchers performed an in vitro analysis to isolate ultralong bovine heavy chains that showed binding with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and related coronaviruses (CoVs).

24 Oct 2022

What is the efficacy of mulberry component Kuwanon C against COVID-19?

A recent study determined the underlying antiviral mechanism of KC associated with the inhibition of SARS-CoV-2.

24 Oct 2022

What are the health benefits and food industry applications of wine industry by-products?

A new article reviewed the health benefits and food industry applications of the by-products of the wine industry.

24 Oct 2022

Longitudinal cohort study of primary healthcare workers reveals long-lasting SARS-CoV-2 humoral immunity in the absence of vaccination

Researchers performed a longitudinal cohort study to assess the levels of immunoglobulins M (IgM), G (IgG), and A (IgA) against the spike and nucleocapsid proteins of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

24 Oct 2022

Compact rapid detection kit to test for monkeypox virus shows promising results in new research

In a new study, researchers introduced a compact rapid detection kit that tests for the monkeypox virus using a combination of RPA and CRISPR technology.

24 Oct 2022

Study shows hybrid immunity or vaccine boosters elicit plasma neutralizing activity against Omicron sublineages

Researchers evaluated imprinted antibody responses against SARS-CoV-2 Omicron sublineages.

24 Oct 2022

The Black Death may have influenced the evolution of genes involved in immune responses against pathogens

Researchers gathered empirical evidence that past pandemics due to infectious pathogens shaped the present-day susceptibility of humans to diseases, such as autoimmune diseases.

24 Oct 2022

A novel approach for viral genomic surveillance

In a recent study posted to the bioRxiv* preprint server, researchers in the United States explored a novel technique to improve representation in viral genomic surveillance.

24 Oct 2022

Research suggests that ORF6 is a major SARS-CoV-2 innate immune antagonist

In a recent study posted to the bioRxiv* server, researchers in the United States demonstrated how severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) open reading frame 6 (ORF6) protein contributes to viral pathogenesis and modulates the host's immune responses.

23 Oct 2022

Immune response in SARS-CoV-1 survivors after COVID-19 vaccination

Researchers evaluate SARS-CoV-2 vaccine-induced immune responses in SARS survivors.

23 Oct 2022

Overview of the roles of neutrophils in systemic autoimmune and autoinflammatory diseases

Researchers assess the role of neutrophil extracellular traps (NETs) in systemic autoimmune and autoinflammatory disorders.

23 Oct 2022

FebriDX point-of-care immunoassay can rapidly determine if an infection is bacterial or viral

Researchers explore whether FebriDx could differentiate between bacteria- and virus-induced immune responses during acute respiratory infection.

23 Oct 2022

Booster vaccinations in the elderly lead to impaired neutralization of SARS-CoV-2 and atypical B cells

Researchers examine neutralizing antibody responses against SARS-CoV-2 in elderly individuals who received one mRNA booster dose.

23 Oct 2022

Study indicates that the major determinants of SARS-CoV-2 pathogenicity reside outside of the spike protein

Researchers at Boston University made a chimeric recombinant SARS-CoV-2 encoding the spike glycoprotein gene of Omicron in the backbone of an ancestral SARS-CoV-2 isolate.

22 Oct 2022

TANGO2 plays a role in heme homeostasis, research reveals

Heme, the iron-holding molecule that gives blood its red color, is essential for life. Yet, ironically, it can be quite toxic if not properly handled. In fact, numerous diseases – from various cancers to cardiovascular diseases – are associated with defects in heme homeostasis.

21 Oct 2022

Anthelmintic inhibits exacerbated inflammatory response related to COVID-19 in preclinical research

Experiments involving animals and human cells conducted at the University of São Paulo (USP) in Brazil suggest that niclosamide, an anthelmintic widely used against tapeworms, effectively inhibits SARS-CoV-2 replication as well as the exacerbated inflammatory response that leads to death in many patients with severe COVID-19.

21 Oct 2022

Protein C News and Research

Researchers design a COVID-19 vaccine construct using hybrid SARS-CoV-2 spike protein and nucleocapsid protein peptides

Study reveals how SARS-CoV-2 infection of macrophages promotes inflammatory responses

Novel oxytocin derivative can reverse Aβ25-35-induced cognitive impairment in mice

Variations in low-complexity regions in monkeypox genome found to impact virus transmissibility

Bovine ultralong complementarity-determining region H3 found to cross-react with sarbecoviruses

What is the efficacy of mulberry component Kuwanon C against COVID-19?

What are the health benefits and food industry applications of wine industry by-products?

Longitudinal cohort study of primary healthcare workers reveals long-lasting SARS-CoV-2 humoral immunity in the absence of vaccination

Compact rapid detection kit to test for monkeypox virus shows promising results in new research

Study shows hybrid immunity or vaccine boosters elicit plasma neutralizing activity against Omicron sublineages

The Black Death may have influenced the evolution of genes involved in immune responses against pathogens

A novel approach for viral genomic surveillance

Research suggests that ORF6 is a major SARS-CoV-2 innate immune antagonist

Immune response in SARS-CoV-1 survivors after COVID-19 vaccination

Overview of the roles of neutrophils in systemic autoimmune and autoinflammatory diseases

FebriDX point-of-care immunoassay can rapidly determine if an infection is bacterial or viral

Booster vaccinations in the elderly lead to impaired neutralization of SARS-CoV-2 and atypical B cells

Study indicates that the major determinants of SARS-CoV-2 pathogenicity reside outside of the spike protein

TANGO2 plays a role in heme homeostasis, research reveals

Anthelmintic inhibits exacerbated inflammatory response related to COVID-19 in preclinical research

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Latest News